<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33887

Description U-box domain-containing protein 33
SequenceMALVSSVPAVTQHIGRITYHDISGLMAGSGGEIVEEPTERLVENTIYVAIGKDVKESKSTLVWALQNSGGKKICILHVHVPAQMIPLLGTRFPASSLKDQEVRAYREIERQNMNKILDEYLLLCRRMGVQAEKLFIEKDCIEKGIIELISQHNIRKLVMGAAADKYYSRKVMDLKSKKAIFVREQAPGSCHINFTCKGHLIHTRSGDDIEFRSLSVQPSPNTETGQINHLRSQSVNLRQNSRPALTSPAQELFRRVRSANIEKSGGTMTDVSSLDGTEGLSTPRNRTDSVGSYDEWYGLPRGSPSPGSGYSTCSSTPMLDVALVPFARNEGSETGSEISALTHSKEDINHSSPPSVLEGSIDDTLYDHLEQSLAEAENAKREAFQEAVRRGKAEKDAINAIRRAKESEILYAEELKHRKDTEEALRREREELNKMKKQRDEVMEELRAAQSQKTSLENQIAESDKMVKNLEQKIISAVDLLQSYKKEREEFQMERDNALREAEELRRKQGEDTSTQMPQFFSEFSCSEIEEATDNFNPSLKIGEGGYGSIYKGLLRHTQVDVLSKLRHPNLVTLVGACPEAWTLVYEYLPNGSLEDRLCCKENTPPLSWQARIRIATELCSVLIFLHSSKPHSIVHGDLKPANILLDANFVSKLSDFGICRLLSHGESSSNNTTICCRTDPKGTFAYMDPEFLSTGELTSKSDVYSFGIILLRLLTGRPALGITKEVQYALDNGKLKTLLDPLAGDWPFVQAEQLARLALRCCEMNRKSRADLGSDVWRVLEPMRASCGGSPSFRLGSGEHFQPPPYFICPIFQEVMQDPHVAADGFTYEAEALRGWLDSGHDTSPMTNHKLEHCNLVPNHALRSAIQEWLQQH
Length874
PositionTail
OrganismMorus notabilis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Moraceae> Morus.
Aromaticity0.06
Grand average of hydropathy-0.482
Instability index52.51
Isoelectric point6.01
Molecular weight97805.65
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



ECO:0000256	ARBA:ARBA00003861

GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33887
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.67|      52|      56|     399|     454|       1
---------------------------------------------------------------------------
   98-  133 (32.08/20.14)	..........................KD..QEVRAYREiERQNMNKILDEYL...LLCRRMgvQAEK.
  399-  454 (75.07/77.93)	NAI......RRAKESEILYAEELkhrKDtEEALRRERE.ELNKMKKQRDEVM...EELRAA..QSQKT
  458-  513 (66.52/53.67)	NQIaesdkmVKNLEQKIISAVDL......LQSYKKERE.EF.QM..ERDNALreaEELRRK..QGEDT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.67|      21|      25|     198|     220|       2
---------------------------------------------------------------------------
  198-  220 (30.78/31.87)	GHLIHTRSgDDIEFRSLSvQP...SP
  225-  248 (33.89/23.21)	GQINHLRS.QSVNLRQNS.RPaltSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     185.42|      59|     283|     516|     582|       3
---------------------------------------------------------------------------
  516-  582 (90.70/84.00)	QMPQFfseFSCSEIEEATDnfNPslKIGEGGY...GSIYKGLLR..H.TQVDVLSKLRHPNLV...TLVGACPEaW
  803-  870 (94.72/62.12)	QPPPY...FICPIFQEVMQ..DP..HVAADGFtyeAEALRGWLDsgHdTSPMTNHKLEHCNLVpnhALRSAIQE.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.62|       9|      15|     283|     292|       5
---------------------------------------------------------------------------
  283-  292 (14.18/12.59)	PRNrTDSVGS
  300-  308 (18.43/10.56)	PRG.SPSPGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.03|      53|     318|      18|      71|       6
---------------------------------------------------------------------------
   18-   71 (84.51/54.23)	TYHDISGLmAGSGGEI..VEEPT..ERLVENTIYVAIGKDVKESKSTLVWALQNS..GGK
  334-  392 (73.52/42.41)	TGSEISAL.THSKEDInhSSPPSvlEGSIDDTLYDHLEQSLAEAENAKREAFQEAvrRGK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33887 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNTETGQINHLRSQSVNLRQNSRPALTSPAQELFRRVRSANIEKSGGTMTDVSSLDGTEGLSTPRNRTDSVGSYDEWYGLPRGSPSPGSGYSTCS
2) VALVPFARNEGSETGSEISALTHSKEDINHSSPPSVLEGSIDDTLYDHLEQSLAEAENAKREAFQEAVRRGK
3) YAEELKHRKDTEEALRREREELNKMKKQRDEVMEELRAAQSQKTSLENQIAES
220
321
411
314
392
463










Molecular Recognition Features






MoRF SequenceStartStop




NANANA