<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33874

Description Uncharacterized protein
SequenceMPDLNLLHVLGGEVMTRVPSNTSTISKISTMSNASDEFAPVVSVTAAFTNTIPPHFESVSSIEISKASVRKDDPGRNDELVRKDHQARKDEPLREYEPVREYNPARKDEPVREDDLKSNSPTQVTTVVFAPATVAVARKSKANELLDRQERAIAALLTRFKNLVLLAALPTEDAFAKETAAAEGLRMEVESNALTSAAEDLLKLTRELKELWTFGPLRGIGEGEGDGEMEADSKKVAELIEKQLEKQHEQEKIKA
Length255
PositionHead
OrganismSclerotinia borealis (strain F-4128)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Sclerotiniaceae> Sclerotinia.
Aromaticity0.04
Grand average of hydropathy-0.525
Instability index35.30
Isoelectric point5.12
Molecular weight28146.41
Publications
PubMed=24459262

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33874
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.90|      15|      15|      81|      95|       1
---------------------------------------------------------------------------
   81-   95 (29.19/16.46)	VRKDHQARKDEPLRE
   99-  113 (29.71/16.85)	VREYNPARKDEPVRE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.34|      34|      37|     131|     165|       2
---------------------------------------------------------------------------
  122-  157 (43.19/31.28)	TQVTTVVF...aPATVAVARKSKANELLdRQERAIAALL
  158-  195 (49.15/30.94)	TRFKNLVLlaalPTEDAFAKETAAAEGL.RMEVESNALT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.39|      20|      33|      18|      37|       3
---------------------------------------------------------------------------
   18-   37 (32.96/24.51)	VPSNTSTIS..KISTMSNASDE
   52-   73 (29.43/21.16)	IPPHFESVSsiEISKASVRKDD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33874 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EISKASVRKDDPGRNDELVRKDHQARKDEPLREYEPVREYNPARKDEPVREDDLKSNSPTQ
63
123










Molecular Recognition Features






MoRF SequenceStartStop




1) MEADSKKVAELIEKQLEKQHEQEKIKA
229
255