<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33847
Description |
Mediator of RNA polymerase II transcription subunit 18 |
Sequence | MHEIFLTALIEDKDFTSARAVLGGLTNMDPWESIQRVLYFQGPQRPMGISNQSSIEKPIRNNTGFLWKELHQNLTRQSFILQTRYDVLKDRDMGANASPMDLDATQGILRWTDFPDPPRGQPLLTQRKKVELWDQKKLPSIMRDNNHIFKTETIEEVYRFYRDDIEFCLTRHYFLQPLEHYTPMETKQQATIPMDTLPPWESLIPVDQQKRWFLQVKAHVVQDNKPDEIRKAQDQLLAVRRELDGVFEFRGIDRKVHDTRVMQPMQGVQQLPQKVTVGK |
Length | 279 |
Position | Head |
Organism | Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium>
Fusarium fujikuroi species complex.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.679 |
Instability index | 50.93 |
Isoelectric point | 7.07 |
Molecular weight | 32872.24 |
Publications | PubMed=20237561
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364150
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP33847
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 154.12| 49| 81| 99| 152| 1
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27- 90 (70.72/32.20) NMDPWESIQRVLYFQGPQR..PMgISNQSSIEkpirnntgfLWKElhqnlTRQSFILQTRYDVLKD
101- 151 (83.41/55.99) DLDATQGILRWTDFPDPPRgqPL.LTQRKKVE.........LWDQ.....KKLPSIMRDNNHIFKT
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