<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33756
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MDELPTRWEIELEYLQYLAQMGKLQEQTFLNYLDYLEYWRDPKYAQFLIYPNCLHILTLLKSPQFREQISRQDLTELLFNDMVNRWKEPIDEKPQEDDKQEQSEQDQAQGQEDGVKKPGQTEPATETV |
Length | 128 |
Position | Middle |
Organism | Kuraishia capsulata CBS 1993 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Saccharomycetales incertae sedis> Kuraishia.
|
Aromaticity | 0.11 |
Grand average of hydropathy | -1.007 |
Instability index | 77.09 |
Isoelectric point | 4.38 |
Molecular weight | 15403.01 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:EnsemblFungi
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | DNA repair GO:0006281 IEA:EnsemblFungi
meiotic gene conversion GO:0006311 IEA:EnsemblFungi
meiotic sister chromatid segregation GO:0045144 IEA:EnsemblFungi
regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
transcription by RNA polymerase II GO:0006366 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP33756
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 52.97| 15| 15| 29| 43| 2
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29- 43 (30.47/19.74) FL...NYLDYLEYWRDPK
47- 64 (22.50/13.11) FLiypNCLHILTLLKSPQ
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.62| 14| 14| 95| 108| 3
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95- 108 (23.31/14.41) QEDDKQEQSEQDQA
111- 124 (24.31/15.31) QEDGVKKPGQTEPA
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