<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33735

Description Mediator complex subunit 23
SequenceTVQMETQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWAGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEFIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSAQRSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVVHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVPIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRNRESLKRKLVHAIIGSLKDNRPQGWCLSDTYLKNAMNAREDNPWVPDDSYYCKLIGRLVAPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGQDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAVSSGSPAPQSTQVPGSLPVTQ
Length1371
PositionTail
OrganismOvis aries (Sheep)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Ruminantia> Pecora> Bovidae> Caprinae> Ovis.
Aromaticity0.10
Grand average of hydropathy-0.003
Instability index46.48
Isoelectric point7.18
Molecular weight156567.29
Publications
PubMed=20809919

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33735
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.96|      19|     127|     908|     926|       1
---------------------------------------------------------------------------
  908-  926 (39.88/29.11)	KENSPEHW.LQNDWHTKHMN
 1038- 1057 (32.09/21.73)	KDNRPQGWcLSDTYLKNAMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.87|      21|     127|     587|     607|       2
---------------------------------------------------------------------------
  587-  607 (36.35/22.33)	FISQLLPTVFKSHAWGILHTL
  613-  633 (38.51/24.13)	YRMHHIQPHYRVQLLSHLHTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.02|      68|     262|     928|    1019|       3
---------------------------------------------------------------------------
  191-  263 (112.55/55.28)	RKLYPEgKLPHWLLGNLVSDFVDTFRPTARI..NSICGRcsLLPVVNNsgAICNSWKLDPA.....TLRFPLKGLLPY.DK
  928- 1003 (110.47/99.47)	HKKYPE.KLYFEGLAEQVDPPVPIQSPYLPIyfGNVCLR..FLPVFDI..VIHRFLELLPVsksleTLLDHLGGLYKFhDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.25|      46|     262|     525|     576|       4
---------------------------------------------------------------------------
  525-  576 (66.24/67.18)	PLPMNLLDSLTVHAKMslIHSIATRVIKLAHAKSSValapALVETYSRLLVY
  790-  835 (81.01/61.99)	PLFLCLLWKMLLETDH..INQIGFRVLERIGARALV....VHVRTFADFLVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      32|     342|     351|       6
---------------------------------------------------------------------------
  342-  351 (18.69/10.69)	IFFVLFQFAS
  375-  384 (19.45/11.45)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.36|      45|     711|      32|      76|      12
---------------------------------------------------------------------------
   32-   76 (85.85/49.79)	TPEDEKTKLISCL.GAFRQFW..AGLSQES........HEQCIQW........IVKFIHGQHSP
  726-  789 (63.51/35.03)	TPHNWASHTLSCFpGPLQAFFkqNNVPQESrfnlkknvEEEYRKWksmtnendIITHFSAQRSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.05|      10|      28|     138|     147|      14
---------------------------------------------------------------------------
  138-  147 (15.61/ 8.57)	RDLLKVILEK
  167-  176 (16.44/ 9.38)	REVIAYILER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.30|      19|     783|      85|     105|      15
---------------------------------------------------------------------------
   85-  105 (31.47/30.13)	CLAMAVETGllPPRMVCESLI
  871-  889 (36.83/27.67)	CLAMRSHEG..NEAQVCYFII
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.29|      51|     856|     271|     321|      20
---------------------------------------------------------------------------
  271-  321 (91.15/60.15)	ALLRYVLE.QP.YSRDMVC...NMLGL..NKQHKQRCPVLEDQLVDLVVYAMERSETE
 1128- 1185 (69.13/43.79)	ALLNVVLKsQPlVPRENITawmNAIGLiiTALPEPYWIVLHDRIVSVISSPSLTSETE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33735 with Med23 domain of Kingdom Metazoa
Unable to open file!