<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33700

Description Mediator complex subunit 23
SequenceMETQLQSIFEDVVKTEFIEEAFAGMFMDNPEDEQTKLVSCLGAFRQYWSTLPQDSHDQCVQWIVRFIHGQHSPKRISFLYDCLAKAVETSLLPPRMVCEALINSDSLEWERTQLWALTFRLIRKIIGGVDYKGVRDLLKALLEKIQSIPNTVSSAVVQQLLTAREVVEYILDRNACLLPAYFAVTEIRKLYPEGKLSHWLLGSLISDFVDSFRATARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLKGLLPYDKDLFEPQTGLLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEQFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMSDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRITLPGTNCMASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQAFFRQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENAPEHWLQSDWHTKHMNYHKKYPEKLYFEGLAEQVNPPVQLTPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRPHLKRKLVHAIISSLKENRTPGWCLSETYLKCAMNAREDSPWVPDDTYYCKLIGRLVDNILLAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGRDVGNSLLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWVVLHDRIVSVISSPTLTSETEWVGEPFQLFDFTACHQSYSEMYCSYVLALAHAVWHHSSIGQLSLIPKFCRRVIKGRITFRLKLKIHLYFNLHYFCQFLHFKAQFCMLKIGVAFYEMLQTVDQYSKHLFYMDPVCDFLYHVKYMFTGDSVKDQVSR
Length1319
PositionTail
OrganismLepisosteus oculatus (Spotted gar)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Holostei> Semionotiformes> Lepisosteidae> Lepisosteus.
Aromaticity0.11
Grand average of hydropathy-0.035
Instability index43.93
Isoelectric point7.71
Molecular weight151649.33
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33700
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      13|      18|     257|     269|       2
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  257-  269 (25.15/15.12)	PYDKDLFEPQTGL
  277-  289 (26.04/15.93)	PYSRDMVCNMLGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.52|      15|      18|    1040|    1056|       3
---------------------------------------------------------------------------
 1040- 1056 (23.08/24.22)	PgWCLSETYLkCAMNAR
 1060- 1074 (32.44/21.02)	P.WVPDDTYY.CKLIGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.54|      11|      18|     481|     493|       4
---------------------------------------------------------------------------
  481-  491 (19.86/ 6.78)	YSTNSECFTLP
  500-  510 (19.69/10.11)	YGNGNMRITLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      18|     351|     362|       5
---------------------------------------------------------------------------
  351-  362 (21.06/11.97)	HMVLSLHQKLAG
  371-  382 (22.76/13.53)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.44|      39|     712|     536|     575|       6
---------------------------------------------------------------------------
  536-  575 (61.18/46.92)	KMSLIHSIATRVIKlAHAKSSLALAPAL................................VETYSRLLVYME
 1225- 1295 (54.26/36.45)	QLSLIPKFCRRVIK.GRITFRLKLKIHLyfnlhyfcqflhfkaqfcmlkigvafyemlqtVDQYSKHLFYMD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.14|      11|      18|     408|     418|       7
---------------------------------------------------------------------------
  408-  418 (22.11/13.14)	CIPVPDINKPQ
  427-  437 (22.04/13.08)	CIWIHLNRKAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     363.26|     148|     711|      20|     200|       8
---------------------------------------------------------------------------
   30-  200 (229.59/213.78)	PEDEQTKLVSCL..GAFRQYWSTLPQDSHDQcvqwIVRFIhgqHSPKRI.SFLYDCLAKAVETSLLPPRMVCEALINSDSLE..W.............................................................................ertqLWAL..........TFRLIRKIIGgvdykgvrdllKALLEKIQSIPNTV.....SSAVVQQLLTAREVV.EYI.......LDR.NACLL......................PAYFAvTEIRKLYPEGKLSHWL
  634-  711 (75.70/33.82)	PQTNQNQLHLCVesTALRLITALGSSEVQPQ....FTRFL...NDPKTVlSAESEELNRALILTLARATHVTDFFTGSDSIQgtW......................................................................................................................................................................................................................
  793-  913 (57.97/25.80)	.....................................................................................ckdilqtimsftphnwashtlscfpaplqaffrqnnvpqesrfnlkknveeeyrkwksmtnendiithfsmqgspplflclLWKMlletdhinqiGFRVLERIGA...........RALVAHVRTFADFLvyefsTSAGGQQLNKCIEILnDMVwkynivtLDRlILCLAmrshegneaqvcyfiiqllllkPNDFR.NRVSDFVKENAPEHWL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33700 with Med23 domain of Kingdom Metazoa
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