<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33699

Description Mediator complex subunit 23
SequenceIQQLSYCFLYLGGSNVEAPLSNFEKTEFIEEAFAGMFMDNPEDEQTKLVSCLGAFRQYWSTLPQDSHDQCVQWIVRFIHGQHSPKRISFLYDCLAKAVETSLLPPRMVCEALINSDSLEWERTQLWALTFRLIRKIIGGVDYKGVRDLLKALLEKIQSIPNTVSSAVVQQLLTAREVVEYILDRNACLLPAYFAVTEIRKLYPEGKLSHWLLGSLISDFVDSFRATARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLKGLLPYDKDLFEPQTGLLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEQFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMSDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRITLPGTNCMASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQAFFRQNNVPQESRFNLKKNVEEEYRKWKSMTNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENAPEHWLQSDWHTKHMNYHKKYPEKLYFEGLAEQVNPPVQLTPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRPHLKRKLVHAIISSLKENRTPGWCLSETYLKCAMNAREDSPWVPDDTYYCKLIGRLVDNILLAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGRDVGNSLLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWVVLHDRIVSVISSPTLTSETEWVGEPFQLFDFTACHQSYSEMYCSYVLALAHAVWHHSSIGQLSLIPKFCRRVIKGRITFRLKLKIHLYFNLHYFCQFLHFKAQFCMLKIGVAFYEMLQTVDQYSKHLFYMDPVCDFLYHVKYMFTGDSVKDQVSR
Length1330
PositionTail
OrganismLepisosteus oculatus (Spotted gar)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Holostei> Semionotiformes> Lepisosteidae> Lepisosteus.
Aromaticity0.11
Grand average of hydropathy-0.032
Instability index43.28
Isoelectric point7.85
Molecular weight152803.60
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33699
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.19|      13|      18|     268|     280|       2
---------------------------------------------------------------------------
  268-  280 (25.15/16.29)	PYDKDLFEPQTGL
  288-  300 (26.04/17.15)	PYSRDMVCNMLGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.52|      15|      18|    1051|    1067|       3
---------------------------------------------------------------------------
 1051- 1067 (23.08/21.47)	PgWCLSETYLkCAMNAR
 1071- 1085 (32.44/18.64)	P.WVPDDTYY.CKLIGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      18|     362|     373|       5
---------------------------------------------------------------------------
  362-  373 (21.06/ 9.52)	HMVLSLHQKLAG
  382-  393 (22.76/10.79)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.14|      11|      20|     419|     429|       9
---------------------------------------------------------------------------
  419-  429 (22.11/14.84)	CIPVPDINKPQ
  438-  448 (22.04/14.77)	CIWIHLNRKAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.69|      40|     885|     310|     349|      12
---------------------------------------------------------------------------
  310-  349 (70.24/44.05)	VLEDQLVDLVVYAMERSETE...EQFD..DGGT................SQLLWQHLS.SQL
 1176- 1237 (47.46/27.44)	VLHDRIVSVISSPTLTSETEwvgEPFQlfDFTAchqsysemycsyvlalAHAVWHHSSiGQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.25|      18|     239|     629|     655|      13
---------------------------------------------------------------------------
  629-  646 (30.92/34.47)	HYRVQLLSHLHSLAAVPQ
  658-  675 (28.33/10.05)	STALRLITALGSSEVQPQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33699 with Med23 domain of Kingdom Metazoa
Unable to open file!