<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33690

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDFQWAINIKKNFPKGATWDYLNLAEALLEQAMIGLSPNPLILSYLKYAISSQMVSYSSILTAVSKFDDFSRELCVKSLLEIMDMFSHQLSCHGKAEECIGLCRSLLAALVWLLQGCAWYSARLREQGEQAGEASLRACVDRLEGLLRGTKNRALIHIARLEEQASWTNVEQAVIRVTENLNSLTNQVLRSKLEECLSLVKSIPLMLVVQAEPPQRTSFPSVHTLVMLEGTMNLTGETQPLVEQLMMIKRMQRIPSPLFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQGEKDFMEDVNIAFEYLLKLTPLLDKADQRCNCDCIELLLQECRKLGLLSEANTSNLSTKRAVDREHAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKPASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEDGKILNPDHPCFRPEPGKVENLVALLNNSSEMKLVQMKWHEICLSTPAAILEVLNAWENGVLTVESVQQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPLYGHSAENTLQFYNERVVIMSSILEHMCADVFQQTGVVLRPPMEGLEPVPYRNLLAPREPIRAALSHQFSEVLQRGWVDSQALHLFESLLHMGGVFWFTNNLVKELLRGTRQEWVMCAVELLYSIFCLDMQQITLTLLGQILPSLLTDSARWHSLADPPGKALAKLAVWCALSSYSTHHKGQASARQRKRQREDIEDYNSLFPLDDTQPSKLMRLLSSNEDDPVILSSPGDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLVSSILSSKTAGPHTQFVQSFMEECVECLEQGSRGSILQFMPFTMVSELVKLTALAKPKVVLAITDLSLPLGRRVAAKAIAAL
Length990
PositionTail
OrganismLepisosteus oculatus (Spotted gar)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Holostei> Semionotiformes> Lepisosteidae> Lepisosteus.
Aromaticity0.07
Grand average of hydropathy-0.009
Instability index45.91
Isoelectric point6.65
Molecular weight110791.80
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33690
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.10|      31|      31|     104|     134|       1
---------------------------------------------------------------------------
  104-  134 (56.41/29.73)	FSHQLSCHGKAEECIGLCRSLLAALVWLLQG
  138-  167 (44.99/22.37)	YSARLREQGEQAGEASL.RACVDRLEGLLRG
  202-  226 (30.70/13.16)	LTNQV.LRSKLEECLSLVKSIPLMLV.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.55|      13|      24|     335|     348|       3
---------------------------------------------------------------------------
  335-  348 (17.86/17.20)	EYLL....KLTpLLDKAD
  357-  373 (14.69/ 6.47)	ELLLqecrKLG.LLSEAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.74|      31|      88|     534|     592|       4
---------------------------------------------------------------------------
  537-  569 (47.58/69.78)	NPDHPCFRPEPGKvENLVALLnNSSEMKLVQMK
  865-  895 (53.15/17.09)	NEDDPVILSSPGD.RSMSSSL.SASQLHTVNMR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.14|      14|      16|     272|     287|       6
---------------------------------------------------------------------------
  282-  298 (16.96/15.12)	WKAcFT.glIESPEGTEE
  301-  317 (20.17/ 6.29)	WTA.FTflkIPQVLLRLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33690 with Med24 domain of Kingdom Metazoa
Unable to open file!