<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33676

Description "Transcription elongation factor A (SII), 1"
SequenceMGKKEEEEIIRIAKKMDKMAQKKNASGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDEPGGGEKVSEEKKKEPTPPTPTSASTRSSPEPREESSSSSNSSSKSETGDAPPNTLITTFPQAPNTSDSVRLKCREMLSSALQSGNDYIAIGADCDELGAQIEESLLQEFKNTDMKYKNRVRSRIANLKDVKNPNLRRNVLCGNVPPDRMAKMTAEEMASDELKEMRKNLTKEAIREHQMARTGGTQTDLFCCGKCKKKNCTYTQVQTRSADEPMTTFVFCNECGNRWKFC
Length313
PositionUnknown
OrganismLepisosteus oculatus (Spotted gar)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Holostei> Semionotiformes> Lepisosteidae> Lepisosteus.
Aromaticity0.04
Grand average of hydropathy-0.830
Instability index57.31
Isoelectric point8.79
Molecular weight34917.44
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33676
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.24|      24|     212|      15|      38|       1
---------------------------------------------------------------------------
   15-   38 (40.39/20.48)	KMDKMAQKKNASGALDLLKEL.KNI
  196-  216 (28.83/13.15)	..D.MKYKNRVRSRIANLKDV.KNP
  231-  252 (31.01/14.53)	RMAKMTAEEMAS...DELKEMrKNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.41|      17|     180|      85|     114|       2
---------------------------------------------------------------------------
   85-  101 (28.93/30.56)	GGGEKVSEEKKKEPTPP
  119-  135 (27.48/ 6.09)	SSSSNSSSKSETGDAPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.35|      13|     180|     102|     114|       4
---------------------------------------------------------------------------
  102-  114 (24.77/17.26)	TPTSASTRSSPEP
  284-  296 (24.58/17.08)	TYTQVQTRSADEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.25|      16|      18|     144|     159|       5
---------------------------------------------------------------------------
  144-  159 (28.14/20.04)	QAPNTSDSVRLKCREM
  165-  180 (28.11/20.02)	QSGNDYIAIGADCDEL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33676 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KKEEEEIIRIAKKMDKMAQKKNASGALDLLK
2) LLDEPGGGEKVSEEKKKEPTPPTPTSASTRSSPEPREESSSSSNSSSKSETGDAPPNTLITTFPQAPNTSDSVRLKCREM
3
80
33
159










Molecular Recognition Features






MoRF SequenceStartStop




1) IIRIAKKMDKMA
2) LIKSWKKLL
9
73
20
81