<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33675

Description "Transcription elongation factor A (SII), 1"
SequenceMGKKEEEEIIRIAKKMDKMAQKKNASGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDEPGGGEKVSEEKKKEPTPPTPTSASTRSSPEPREESSSSNSSSKSETGDAPPNTLITTFPQAPNTSDSVRLKCREMLSSALQSGNDYIAIGADCDELGAQIEDCIFQEFKNTDMKYKNRVRSRIANLKDVKNPNLRRNVLCGNVPPDRMAKMTAEEMASDELKEMRKNLTKEAIREHQMARTGGTQTDLFCCGKCKKKNCTYTQVQTRSADEPMTTFVFCNECGNRWKFC
Length312
PositionUnknown
OrganismLepisosteus oculatus (Spotted gar)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Holostei> Semionotiformes> Lepisosteidae> Lepisosteus.
Aromaticity0.04
Grand average of hydropathy-0.820
Instability index54.75
Isoelectric point8.76
Molecular weight34866.42
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33675
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.02|      24|     211|      15|      38|       1
---------------------------------------------------------------------------
   15-   38 (39.41/23.86)	KMDKMAQKKNASGALDLLKEL.KNI
  196-  215 (26.35/13.90)	....MKYKNRVRSRIANLKDV.KNP
  230-  251 (31.26/17.65)	RMAKMTAEEMAS...DELKEMrKNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.14|      30|     179|      85|     114|       2
---------------------------------------------------------------------------
   84-  113 (54.35/30.71)	PGGGEKVSEEKKKEPTPPTPTSASTRSSPE
  114-  133 (24.05/ 9.89)	PREESSSSNSSSKSETGDAP..........
  278-  294 (22.73/ 8.98)	..........KKKN...CTYTQVQTRSADE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.25|      16|      18|     143|     158|       3
---------------------------------------------------------------------------
  143-  158 (28.14/21.55)	QAPNTSDSVRLKCREM
  164-  179 (28.11/21.52)	QSGNDYIAIGADCDEL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33675 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KKEEEEIIRIAKKMDKMAQKKNASGALDLLK
2) LLDEPGGGEKVSEEKKKEPTPPTPTSASTRSSPEPREESSSSNSSSKSETGDAPPNTLITTFPQAPNTSDSVRLKCREM
3
80
33
158










Molecular Recognition Features






MoRF SequenceStartStop




1) IIRIAKKMDKMA
2) LIKSWKKLL
9
73
20
81