<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33666

Description "Transcription elongation factor A (SII), 3"
SequenceMTREEELIRIAKKLDKMVSRNNMDGALDLLKELKGYNMNLKLLQVTRIGMSVNGVRKHCTDEEVVTLAKILIKNWKRLLESAGSQKGETQSGRDSETNSSNPVGAGLTPQPAKHSPDEEDRKQALDSKPSFEPPKKHTFSDQKKERKDSTDSKPPPPPPKHLPVEVRKESSGKDSTDSKSLPPNRSSLVTKKERQGSADAKTIPPKRPSLDVKKERKDSSDSKSAPPVKRPSTDAKPERRDSSDAKSNSSPKKLSIDIKRDRRDSLTSKPSNLSPLPRKPSTESRDERVNSSKGKPEPPKTPTSPTSPLSPSFSPLGGPFPPHLLTGDSIRDKCIEMLSAALRTDDNYKEYGTNCDSMAAEIEDHIYQEIKATDMKYKNRVRSRISNLKDPKNPELRRNVLRGAIELSRIASMTAEEMASDELKQLRNVLTQEAIREHQMAKTGGTATDLFQCAKCRKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Length491
PositionUnknown
OrganismLepisosteus oculatus (Spotted gar)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Holostei> Semionotiformes> Lepisosteidae> Lepisosteus.
Aromaticity0.03
Grand average of hydropathy-1.069
Instability index61.83
Isoelectric point9.51
Molecular weight54870.51
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP33666
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     246.65|      21|      21|     204|     224|       1
---------------------------------------------------------------------------
  112-  134 (29.39/11.77)	AKHSP.D.EEDR..KQALDSK...P.sfeP.P
  135-  159 (32.63/13.86)	KKHTFsDQKKER..KDSTDSKpppP....P.P
  160-  183 (26.64/10.00)	KHLPV.EVRKESsgKDSTDSK...S...lP.P
  184-  205 (27.81/10.75)	NRSSL.VTKKER..QGSADAK...T...iP.P
  206-  227 (38.75/17.81)	KRPSL.DVKKER..KDSSDSK...S...aP.P
  229-  251 (33.82/14.62)	KRPST.DAKPER..RDSSDAK...S..nsS.P
  252-  277 (27.20/10.36)	KKLSI.DIKRDR..RDSLTSK...PsnlsPlP
  278-  299 (30.41/12.43)	RKPST.ESRDER..VNSSKGK...P...eP.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.76|      19|      26|     383|     401|       2
---------------------------------------------------------------------------
  383-  401 (33.89/23.00)	SRISNL..KDPKNPELR..RNVL
  408-  430 (22.87/13.07)	SRIASMtaEEMASDELKqlRNVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.31|      14|      27|     448|     461|       3
---------------------------------------------------------------------------
  448-  461 (28.54/17.56)	TDLFQCAKC..RKKNC
  476-  491 (25.76/15.25)	TTFVLCNECgnRWKFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.75|      16|      18|     324|     341|       5
---------------------------------------------------------------------------
  324-  341 (23.84/23.65)	LLTGDSIRD...KCIEMlsAA
  342-  360 (24.91/16.91)	LRTDDNYKEygtNCDSM..AA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP33666 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LLESAGSQKGETQSGRDSETNSSNPVGAGLTPQPAKHSPDEEDRKQALDSKPSFEPPKKHTFSDQKKERKDSTDSKPPPPPPKHLPVEVRKESSGKDSTDSKSLPPNRSSLVTKKERQGSADAKTIPPKRPSLDVKKERKDSSDSKSAPPVKRPSTDAKPERRDSSDAKSNSSPKKLSIDIKRDRRDSLTSKPSNLSPLPRKPSTESRDERVNSSKGKPEPPKTPTSPTSPLSPSFSPLGGPFPPHLLTGDS
78
329

Molecular Recognition Features

MoRF SequenceStartStop
NANANA