<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33646

Description Uncharacterized protein
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNCPKGATWDYLNLAEALLEQAMIGPSPNPLILSYLKYAISSQVSLLKVHAFDDFSRELCVKSLLEIMDMFSYSLSCQGKAEECIGLCRALLGIVVWLLQGCAWYCEKLREPGLLPAGEASLSACQERLESLLQRTKNRALVHIARLEEQASWSNVEQALIKLVENLSSLSNQTLSNKLEECISLVKSIPQMVCIQCDPPVQTTFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPAPIFVLEVWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQGDKDFMDDMNMAFEFLLKLTPLLDKADQRCNCDCLSLLLQECNKLGLLSESNTANLTGYAPKLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLICSVCFCNVLAKAASVRALLFDISFLMLCHVVQTYGSEVILSEPSPSGETPFFETWLQMCMPEEGKTLNPDHPCFRPESGKVESLVALLNTSSEMKLVQMKWHEICLTTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPLYGENTLQFYNERVVIMSSILEHMCADVFQQTGVSLRPAVEGQEPIPYRSLLPARQPIRQALQAQFRQVLDKGWVDSRTLHLLESLMHMGGVFWFTNNLVKELLKETRKEWAIRVVELLYSIFCLDLQQVTLTLLGHILPNLLTDPAHWHILADPPGRALAKLSVWCALSSYSSHHKVHTLARQRKRQREDIEDYSSLFPLDDTQPSKLMRLLSSNEDEPVVLSSPGDRTMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSKSAGPHTQFVQSFVEECVECSEQGSRGSILQFMPFTMVSELMKLHALAKPKVVLSITDLTLPLGRRVAAKAIAAL
Length974
PositionTail
OrganismAstyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Characiformes> Characoidei> Characidae> Astyanax.
Aromaticity0.07
Grand average of hydropathy0.060
Instability index46.00
Isoelectric point6.52
Molecular weight108917.17
Publications
PubMed=25329095

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP33646
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.01|      35|     560|      85|     120|       1
---------------------------------------------------------------------------
   85-  120 (59.50/41.96)	RELCVKSLLEIM..DMF...SYSLSCQGKAEECIGLcRALL
  646-  685 (50.52/30.05)	RVVIMSSILEHMcaDVFqqtGVSLRPAVEGQEPIPY.RSLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.32|      14|      16|     168|     183|       2
---------------------------------------------------------------------------
  168-  183 (20.27/17.34)	ALVHIarLEEQASWSN
  187-  200 (22.05/11.94)	ALIKL..VENLSSLSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.28|      26|     114|     407|     432|       4
---------------------------------------------------------------------------
  407-  432 (44.10/29.19)	KTVDAD.HS...K.SPE.GLLGVLGHMLSGKS
  522-  549 (35.82/22.23)	KTLNPD.HP...CfRPEsGKVESLVALLNTSS
  552-  579 (25.36/13.44)	KLVQMKwHEiclT.TPA.AILEVLNAWENG..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.69|      12|      19|     232|     243|       6
---------------------------------------------------------------------------
  232-  243 (21.69/13.15)	TFPSVHAFIMLE
  252-  263 (21.00/12.51)	TQPLVEQLMMIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.90|      11|      25|     449|     460|       7
---------------------------------------------------------------------------
  449-  460 (15.42/16.31)	FARKFInLICSV
  477-  487 (21.48/15.99)	FDISFL.MLCHV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP33646 with Med24 domain of Kingdom Metazoa

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