<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33634

Description "Transcription elongation factor A (SII), 2"
SequenceMVKDQEVERIAKKLDKMVQKENTDGALDLLKELKNMKMSLETLQSTRIGMSVNAVRKQSSDDEVQSLAKSLIKAWKKLLDGAEGKSEEKNKGGPSLQSSTSSSTTSSKDSPGSSDSKKPETPKTPTTPTTPTTPKFTSFPPVPVTTDSVRTKCRELLVAALQTDDDYKNIGSDCDTLAAEIEDYILLNQTCSEFKSTDMKYKTRLRSRISNLKDQKNPDLRRNVLCGNISTERIATMTAEEMASAELKEMRKALTKESIREHQLSKVGGTETDMFICGKCKGKKCTYTQVQTRSADEPMTTFVLCNDCVWGCWGCFCV
Length318
PositionUnknown
OrganismAstyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Ostariophysi> Characiformes> Characoidei> Characidae> Astyanax.
Aromaticity0.04
Grand average of hydropathy-0.681
Instability index48.36
Isoelectric point8.49
Molecular weight35277.86
Publications
PubMed=25329095

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33634
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.75|      10|      15|     165|     174|       2
---------------------------------------------------------------------------
  165-  174 (19.32/11.13)	DDYKNIGSDC
  182-  191 (18.43/10.37)	EDYILLNQTC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33634 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ERIAKKLDKMVQKENTDGALDLLKELKNMKMSLETLQSTRIGMSVNAVRKQSSDDE
2) LDGAEGKSEEKNKGGPSLQSSTSSSTTSSKDSPGSSDSKKPETPKTPTTPTTPTTPKFTSFPPVPV
8
79
63
144










Molecular Recognition Features






MoRF SequenceStartStop




1) LAKSLIKAWKKLLD
67
80