<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33626

Description Thyroid hormone receptor-associated protein 6
SequenceMSGQFTGGYQSPSGHRGNYNSPMIQQQLNQMNVPGQMGMMGFNQGNVMNAQQMQVGPGQGNQEMVMNQGMMGQPQNQQQGGPGMQGNAQQLGMGQQQQGGNQMVSQVGQHQGPQPSPQMGMQQQQQQQQQQQQMVHVPHGNMMSGAPQGQNQGSQGPNQPGGVGPTAVQQQQKAEFNLFSLCRIGQETVQDIVSRFQEVFGILRAIQPPNGTNQGQLSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDTCQQGMEYTHMESLIPLKGEVVRSEPVHTEEYKKALQENRELVAMVQLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length325
PositionHead
OrganismAnopheles darlingi (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-0.859
Instability index49.28
Isoelectric point9.23
Molecular weight36351.84
Publications
PubMed=20920257
PubMed=23761445

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33626
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.40|      17|      20|      67|      84|       1
---------------------------------------------------------------------------
   43-   59 (28.99/ 6.21)	NQGNVMNAQ.QMQVGPGQ
   67-   84 (36.41/12.49)	NQGMMGQPQnQQQGGPGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.09|      27|      27|      92|     118|       2
---------------------------------------------------------------------------
    1-   22 (31.31/ 7.13)	.MSGQFTGGYQ..SPSG.HRGNYNS..P.
   92-  118 (55.26/18.83)	GMGQQQQGGNQMVSQVGQHQGPQPS..PQ
  120-  148 (45.52/14.07)	GMQQQQQQQQQQQQMVHVPHGNMMSgaPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.42|      48|      56|     156|     211|       3
---------------------------------------------------------------------------
  158-  211 (70.93/60.39)	NQpGGVGP....TAVQQQqkaeFN....LFSLCRIGQETVQDIVSRFQEvFGILRAIQPPNG
  213-  268 (74.49/39.49)	NQ.GQLSSndkkAKVQEQ....FRtirlLFKRLRLLYDKCNDTCQQGME.YTHMESLIPLKG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33626 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSGQFTGGYQSPSGHRGNYNSPMIQQQLNQMNVPGQMGMMGFNQGNVMNAQQMQVGPGQGNQEMVMNQGMMGQPQNQQQGGPGMQGNAQQLGMGQQQQGGNQMVSQVGQHQGPQPSPQMGMQQQQQQQQQQQQMVHVPHGNMMSGAPQGQNQGSQGPNQPGGVGPTAVQQ
1
170










Molecular Recognition Features






MoRF SequenceStartStop




NANANA