<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33625

Description Thyroid hormone receptor-associated protein complex 100 kDa component
SequenceMIIDSPKTTSKTTLLKLMLLRAWKERWTDCQWGINVKTVLTRGVSGDVYNLADAIIQQAVVGSGANMLFLSYLKHSLCAHLISHAAVLNRIAKYEHFDKHHCLIALLDFLQSIIDGVTCRGKQEESILTKAVVSLVHWLIQIYECAIKSYAENHALTAEEETVVQKVATVLERIVDSPFLLGVLSIGKYETPDLFLALQHRFNGINNLTITTGYVAQVPGSQKNPVTVTDCMRKLVLIELDASEMKLFDGGVVEPITYCLQPLLAVEVLLNPMSDTTQYVSQLINLRRLKGFSNARLYCELVRGCFISLNNVEGTSKESLLCAFAFIRVPHIMRQIHGRLNGKEQTEETTNQTYSVDVVEAFEMLLQDTPVLDYMDMKCACNVVECLLKELAKHNLVTELHVKQFVTQREPSTLCLQKLETSNTQLAMMLKFVFRVESPLAGILKALSTDFSKVQDALLAMLCQVLTGNGLDLVLSVASVEGKFKALVSGLLKCNDYAKQATTVELGKAPATRAALFDVTFMMLAFVAQSYGSDAILAEGGNTFFEKWVREFMVERKKTKSPMTMVKQADPMVLEELIMALNNTDAGLKTSNLRWEDICYTIPALLHQVLMAWENETLSPVEIKKMLDGLKAQFCSFAVCSASWLCAYMQMVRQDEQVKPMNMVQQLCTALTGPQAEEWQQQDYGKDRFTLMGQLIRKMQQEFQRMPQINPKLKALFPSQHMVSHLPLEEQFEEAWKAVAERGWLPIETTFLFDTLLQSCGPLWLVEKLIAKLFLCKYVRELNKTMDLIFAIMHLDIERCTIALLSQLVPMMLLNKQQTPEIVDPQSRVLAKLCVYCIIVTMENSLTTTKKRARQPGGPADAEDLDTLCSNAKLRKIELDGMGVGCASDTVTAEFSLDSALDGNGWEVTTVSLKEPLQGCLQTLFRTFTQYITTNELSPKVYFVFQFLSLLVEIGRDRIMCVLKLIPNGLIQNLLKINATDEVTVGLILRYVPLACNLVPHGELYSVINIIARCNARGRSTITMSSSRCNSKKC
Length1034
PositionTail
OrganismAnopheles darlingi (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.07
Grand average of hydropathy0.107
Instability index37.20
Isoelectric point6.45
Molecular weight116044.63
Publications
PubMed=20920257
PubMed=23761445

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33625
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     201.00|      67|     154|     749|     822|       1
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  749-  822 (101.28/96.54)	TTFLFDTLLQSCgplwlVEKLIaKLFlCKYV..RELNKTMDLIFAIMHLDIE..RCTIALLSQLVP....MMLLNKQQTPEI
  909-  983 (99.72/71.54)	TTVSLKEPLQGC.....LQTLF.RTF.TQYIttNELSPKVYFVFQFLSLLVEigRDRIMCVLKLIPngliQNLLKINATDEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.59|      16|      95|     548|     568|       2
---------------------------------------------------------------------------
  553-  568 (28.70/25.23)	MVERKKTKSPMTMVKQ
  651-  666 (29.89/12.47)	MVRQDEQVKPMNMVQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     213.28|      70|      93|     375|     453|       3
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  375-  453 (108.55/96.97)	MDMKCACNVVECLLKELAKHNLVTELHVKQfvtqrePSTLCLQKLETSNTQL....AMMLKFV...FRVESPLAgilKALSTDFSK
  471-  547 (104.74/72.58)	LDLVLSVASVEGKFKALVSGLLKCNDYAKQ......ATTVELGKAPATRAALfdvtFMMLAFVaqsYGSDAILA...EGGNTFFEK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.32|      54|     636|     206|     264|       4
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  111-  175 (71.99/45.59)	Q..SIIDGVTCR..GKQEESI.LTKAVVSLVhwLIQIYECAIKSYaenhaltaeEETVVQKVATVLERIV
  206-  264 (78.33/67.34)	NnlTITTGYVAQvpGSQKNPVtVTDCMRKLV..LIELDASEMKLF.........DGGVVEPITYCLQPLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33625 with Med24 domain of Kingdom Metazoa
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