<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33617

Description CRSP complex subunit 3
SequenceMSTELRILKLFEEVLEDKNIPNCDEEEQRKRADEGYKKIAAVFAAMPGDQAIQAVRNYIGHFTGGGTDGGTMNHQNRVQMYLRVLERMIALNIIPAKLVCDQLMGSEKLTYKNSCFWIESFRLVRKIIGGVDYKGVREIMKCCKEKALSFPVNVSVNILPQLLELIELIEHIFNRSACLLPAYFIINEIKKTDYQNMHWRVSNLIANFIEEFVAVAQMLSIIGHSSMLPIVEHSSYADNLIIPWKLDPDTLKLSLRGNLPYDDELLQPQARLLRFVLQQPYSRDMVCSMLNFQKQQKQKCAALEEQLVWLVLNAMEYSEKENQTTGGQGNGGPNGEHDDGASSHTQWVWLHLSSQLIYFVLFQFATFQNIVNTLHEKLAVRNLRRGRDHLMWVFLQYISGSIQKHSILNFLPVLKLYDILYPEKEPLPVPDYNNPYCTHQMAPTCIWIHLMKRAQTENYNINRPIPIALRLHFDYLQHLAMPSNNPTLFMGSEYRFALLCNAYSTQTDYFSRPMQALIDTILGNSKNPQANMSGQPLPTAPLSMRVLDSLTIHSKMSLIHSIVMHMIKQAQNKSSIPNGNNMAPALVETYSRLLVYTEIESLGIKGFLGQLLPQVFKSHAWGILYTLLEMFSYRMHHIHSHYRVQLLTHLHSLASVPHTNQMQLHSCVESTALRLIIGLGSVEVQAQLSRYVSEPKPPGNIVSAESEELNRALILTLARSMHITGTGSDPQSSAWCKDLLQNIMVNTPHAWPQHTLLCFPQVLNEFFMQHNIPKESKQLLKKTVDEEFRNWASMTNENDIIAHFGMAVNPPLFLCLVFKMIIETDAISPVAYKILERIGARALSTHLRKLCDYLLFEVANSGGGAHVNKCVDTINDMIWKYNIVTIDRLVLCLILRTLDGNEAQVSFYIIQLLLLKTSEFRNRVQEFITINSPEHWKQNNWHERHLAFHQKFPEKFAPDESVSHPTLPVYFGNVCLRFLPVLDIIVHRYLEVPTQLSKTLDVILDHLGSLYKFHDRPITYLYNTLHYYEVKLRDRPLLKKRLVGTVVGSLKDVRPENWALTEQYQAYMVKKENDNANWVPELSYYIHLVGRMQDTMDGKNVFSGTDWRFNEFPNPPAHALYVTCVELLGLPVGPSVVANSIIDVLVKGYTVVPTGVVHNWANTIGLIMAALPEAYWCVIYERMQEALRSPAMKQWTYRQSPFEMFNFKVVREAMLDRSYVTVLAIVHSTFHHFGIGQLATITDSIKEKLKPLVQTEYQLIYLCHVVGPFLNRLSVERARAVSDITLMLYELLEQVDKAQPTQPLRYMDPICDLLYHIKYMFVGDTMKTDLEAIIRRLRPALQMRLRFITRLNVEEIGVDQNANAGATGPGTGVAAGGTGVPGGGSMPAQQTGSTQMAVGANVGGVVGGGVGIGAQSAGQGVAVGAAVAAAAAAAAAAQQSAVGMVNQNVALQQQLQQQKQQQQQQMGQGMQQHH
Length1474
PositionTail
OrganismAnopheles darlingi (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.09
Grand average of hydropathy-0.098
Instability index44.71
Isoelectric point7.47
Molecular weight166895.15
Publications
PubMed=20920257
PubMed=23761445

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33617
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     429.04|     106|     259|     922|    1029|       1
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  922- 1029 (183.53/108.23)	NRVQE...FI........TINSPEHWKQNNWHERHLAFHQ...KFPEKFAPDES......VSHPTLPVYFGNVCLRFLPVLDIIVHR...YLEVPTQL....SKTLDVILDHLGSLYKFHDRPITYLynTLHYYE
 1077- 1175 (105.96/55.84)	NWVPElsyYIhlvgrmqdTMDGKNVFSGTDWR.....FNE....FPNPPAHALY......VTCVELLGLPVGPSVVANSIIDVLVKG...YTVVPTGVvhnwANTIGLIMAALPEAY..................
 1181- 1290 (139.54/76.38)	ERMQE.............ALRSPA.MKQ..WTYRQSPFEMfnfKVVREAMLDRSyvtvlaIVHSTFH.HFG..IGQLATITDSIKEKlkpLVQTEYQL....IYLCHVVGPFLNRLSVERARAVSDI..TLMLYE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.38|      30|     101|     317|     352|       5
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  317-  352 (45.57/35.33)	YSEKENQTTGGQGNggPNGEHDDGASShtqwVWLHL
  421-  450 (60.81/29.66)	YPEKEPLPVPDYNN..PYCTHQMAPTC....IWIHL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     280.24|      91|     129|     547|     647|       6
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  547-  647 (141.80/123.34)	LDSLTIHSKMSlihsivmHMIKQAQNKSSI..PNGNNMAPALVETYSRLLVYT.....EIESLGIKGFLGQLLpqVFKSHAWGiLYTLL...EMFS.YRMHHIHSHYRVQLL
  679-  780 (138.44/94.88)	LGSVEVQAQLS.......RYVSEPKPPGNIvsAESEELNRALILTLARSMHITgtgsdPQSSAWCKDLLQNIM..VNTPHAWP.QHTLLcfpQVLNeFFMQHNIPKESKQLL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.88|      21|      23|    1379|    1400|       7
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 1379- 1400 (37.79/25.48)	GVPGGG.SMPAQQTGStQMAVGA
 1404- 1425 (35.09/18.99)	GVVGGGvGIGAQSAGQ.GVAVGA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.41|      19|     749|      83|     115|      12
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   93-  111 (35.55/51.71)	IIPAKLVCDQLMGS..EKLTY
  241-  261 (32.86/10.01)	IIPWKLDPDTLKLSlrGNLPY
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.33|      28|     313|     474|     513|      14
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  474-  511 (42.08/46.65)	DYLQHLAMpSNNPTLFmgseyrfalLCNAYS..TQTDYFS
  799-  828 (47.24/24.37)	DIIAHFGM.AVNPPLF.........LCLVFKmiIETDAIS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33617 with Med23 domain of Kingdom Metazoa
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