<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33606

Description Mediator complex
SequenceMASSSNGSGNLVDELEEAFQSCIHALTKEESATGIDKDEIKVEVDQTTLKFIDLARQMEAFFLQKRFLLSALKPDLLLKEENFDLKQEIARKDELIRKHYEKIETWKQLLSDQQNFNKPIQSLPPDMRGNLAGGAPGGAPGAIMPGGGMGLPMQNMSQVQQMQNQHQQQQQMQQLQAQQQQMQQQMQQSLPMGAGNAQLFQQGGVPRGVGQGGGPGPGFPPGAGPNLQGPLAYLEKTASNIDLVGMGDGRR
Length251
PositionHead
OrganismAnopheles darlingi (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.05
Grand average of hydropathy-0.636
Instability index52.33
Isoelectric point5.30
Molecular weight27396.74
Publications
PubMed=20920257
PubMed=23761445

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33606
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.09|      16|      17|     153|     168|       1
---------------------------------------------------------------------------
  153-  168 (32.66/13.64)	MQNM.SQVQQMQNQHQQ
  172-  188 (27.43/10.49)	MQQLqAQQQQMQQQMQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.99|      28|      65|     122|     150|       2
---------------------------------------------------------------------------
  122-  150 (52.06/24.92)	SLPPDmRGNLAGGAPGGAPGAIMPGGGMG
  189-  216 (54.93/23.01)	SLPMG.AGNAQLFQQGGVPRGVGQGGGPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.93|      30|      32|      53|      84|       3
---------------------------------------------------------------------------
   53-   84 (43.91/36.02)	DLARQMEafFLQKRFLLSALKPDLLLKEENFD
   88-  117 (51.02/34.77)	EIARKDE..LIRKHYEKIETWKQLLSDQQNFN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33606 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QNFNKPIQSLPPDMRGNLAGGAPGGAPGAIMPGGGMGLPMQNMSQVQQMQNQHQQQQQMQQLQAQQQQMQQQMQQSLPMGAGNAQLFQQGGVPRGVGQGGGPGPGFPPGAGPNLQGPLAYLEKTASNIDLVGMGDGRR
114
251










Molecular Recognition Features






MoRF SequenceStartStop




NANANA