<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33602

Description Ring finger protein
SequenceMGMQERNRHSMSGSAIDRHSGHFESSSNSSRGSELHVDTRSVMSMSDTLRNSRDNNRDRISPPYHLVGNNGGGSGGSNGSGIGSSSSSGASGSSGINQAPSSSYCPIEGGPMGMNSGGVGGGMKSDSPSRKRRRVSSRLPSQSPPAIWEHRRSPRNGLGGAGGVGGSGMMMLGGNGSGGMMNGHHNMSLQQPQTVSQSAQMHLQQQQQQQQQQQQQQQQQQQQQQQQQQLLHREQQQHHHHASHHHHHGHSQHQQQQHHHTNGGPHTMHPSTAGSGLAAAVMSQLQSHMHPQGSPPVRRPRYHRDQHQQQQQQQQQQQQQQQQPPPPPPPQQQQRPWDQLTAVFQQQSPATVAQHQHAPSSLMVDINQVPVSLPLGHHHEQLWTYSAGPHISICSGHPAAPHLPPCQVHGVYSQPLVQTCGIGGHFGGFASTTGPALAVPHPPPHQAHYTHPHLAQQHRTDGLALDGLEHAGASPLHISPLTTHAHLHSTPQMTQLTAAAQPIYISTEGRSSQFELLHRTARRAISAPRRNFARFHWPAPAPPPPPPPPPAHHHHHHHHHHPATHRSPPALQHQGPLGPQPAHVTLSATTSAYSGILLNFLAMFPLSTYGPPDLNSPDSNETENYEALLSLAERLGEAKPRGLARPEIDQLPSYKFNAETHTGDQTSCVVCMCDFEARQILRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASEYFESSEEQ
Length722
PositionTail
OrganismAnopheles darlingi (Mosquito)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Anophelinae> Anopheles.
Aromaticity0.04
Grand average of hydropathy-0.916
Instability index76.68
Isoelectric point8.77
Molecular weight78850.08
Publications
PubMed=20920257
PubMed=23761445

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33602
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     439.91|      94|     100|     166|     265|       1
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  166-  265 (180.83/48.47)	GSGMMmlggngSGGMMNG.HHNMSLQQPQTVSQSAQMHLQQQQQQQQQQQQQQQQQQQ.......QQQQQ..QQLLHR............................EQQQHHHHASHHHHHGHS...QHQQ......QQ..HHHTN.....GGP
  274-  389 (131.88/29.44)	GSGL.......AAAVMSQlQSHMHPQGSPPVRRP.RYHRDQHQQQQQQQQQQQQQQQQpppppppQQQQRpwDQLTAV............................FQQQSPATVAQHQHAPSSlmvDINQvpvslpLG..HHHEQlwtysAGP
  465-  579 (127.21/28.14)	LDGLE..............HAGASPLHISPLTTHAHLHSTPQMTQLTAAAQPIYISTE.......GRSSQ..FELLHRtarraisaprrnfarfhwpapappppppPPPAHHHH..HHHHHHPA...THRS......PPalQHQGP.....LGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.13|      14|      14|      73|      86|       2
---------------------------------------------------------------------------
   73-   86 (26.55/10.42)	GSGGSNGSGIGSSS
   89-  102 (23.00/ 8.14)	GASGSSGINQAPSS
  115-  127 (23.59/ 8.52)	NSGGV.GGGMKSDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.19|      16|     102|     429|     444|       4
---------------------------------------------------------------------------
  429-  444 (34.01/13.45)	FASTTGPALAVPHPPP
  532-  547 (37.18/15.44)	FARFHWPAPAPPPPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.91|      15|      16|       2|      16|       6
---------------------------------------------------------------------------
    2-   16 (26.95/13.30)	GMQERNRHSMSGSAI
   21-   35 (24.96/11.80)	GHFESSSNSSRGSEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.04|      25|      26|     600|     625|       9
---------------------------------------------------------------------------
  600-  625 (41.62/28.69)	FLAMfPLSTYGPPDLNSPDSNETENY
  630-  654 (41.41/23.47)	SLAE.RLGEAKPRGLARPEIDQLPSY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33602 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) APRRNFARFHWPAPAPPPPPPPPPAHHHHHHHHHHPATHRSPPALQHQGPLGPQPAHVT
2) MGMQERNRHSMSGSAIDRHSGHFESSSNSSRGSELHVDTRSVMSMSDTLRNSRDNNRDRISPPYHLVGNNGGGSGGSNGSGIGSSSSSGASGSSGINQAPSSSYCPIEGGPMGMNSGGVGGGMKSDSPSRKRRRVSSRLPSQSPPAIWEHRRSPRNGLGGAGGVGGSGMMMLGGNGSGGMMNGHHNMSLQQPQTVSQSAQMHLQQQQQQQQQQQQQQQQQQQQQQQQQQLLHREQQQHHHHASHHHHHGHSQHQQQQHHHTNGGPHTMHPSTAGSGLAAAVMSQLQSHMHPQGSPPVRRPRYHRDQHQQQQQQQQQQQQQQQQPPPPPPPQQQQRPWDQLTAVFQQQSPATVAQHQHAPSSLMVDINQVPV
3) STTGPALAVPHPPPHQAHYTHPHLAQQHRTDGLALDGLEHAGASPLHISPLTTHAHLHSTPQMTQLTAAAQPIYI
527
1
431
585
371
505










Molecular Recognition Features






MoRF SequenceStartStop




NANANA