<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33590

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMPTPIRQRSPMPTKQFLSPPSVDPEPFYLLKDPPISGPGSEVTGETHMISHYGLEHSYNKFSTKKLKEQLSAFLPLLPGNIDTVSSQDNSSLQSVIEKPPITKEITTFTTGMLQGFKLHPGSIPDQYKLLHHQPAKKHKHKKHKRDHRIPELSEPMSAGAEAGGDNGHEKKHKKTKKHGDQDGEKKKRDKKKKKKKARQDPMHPGMPATHEGSGPGRP
Length218
PositionHead
OrganismStrongylocentrotus purpuratus (Purple sea urchin)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-1.175
Instability index61.67
Isoelectric point9.80
Molecular weight24352.57
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33590
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.77|      12|      31|     136|     147|       1
---------------------------------------------------------------------------
  136-  147 (23.54/10.09)	KKHKHKKHKRDH
  170-  181 (22.23/ 9.18)	KKHKKTKKHGDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.55|      11|      41|      70|      81|       3
---------------------------------------------------------------------------
   70-   81 (16.70/13.85)	LSAFlPLLPGNI
  113-  123 (21.85/13.15)	LQGF.KLHPGSI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33590 with Med19 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TTFTTGMLQGFKLHPGSIPDQYKLLHHQPAKKHKHKKHKRDHRIPELSEPMSAGAEAGGDNGHEKKHKKTKKHGDQDGEKKKRDKKKKKKKARQDPMHPGMPATHEGSGPGRP
106
218










Molecular Recognition Features






MoRF SequenceStartStop




1) EPFYLLKDPPI
2) GHEKKHKKTKKHGDQDGEKKKRDKKKKKKKARQDPMHPGMPATHE
3) YKLLHHQPAKKHKHKKHKRDHRI
25
167
127
35
211
149