<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33589

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMQNQDKVLDNSLDYILSRVNDLKKALTDLLMKLEHHHETLNWPSVLNSFALLSGQINTLNRHLKSDKTPVLKNLIILPLKLSQDRDEELEKVTEGRVASFNHDVVPNYLRTKPEPESEEREQVLAKDAAQLSPEVAKINTLNRHLKSDKSPVKKNLIILPLKLSQDRDEELEKVTEGRVASFNHDVVPNYLRTKPEPESEEREQVLAKDAAQLSPEVAKKQIDNLNRLSTHLLSMLASQRETWDPDSSKLNITTSSPSDTNMLVGAVNMGRGFKRGMVQQPMSNMGAQMARQGDQHAPVGKIPSGIRTNIKSGGGHFNR
Length319
PositionHead
OrganismStrongylocentrotus purpuratus (Purple sea urchin)
KingdomMetazoa
Lineage
Aromaticity0.03
Grand average of hydropathy-0.682
Instability index40.61
Isoelectric point7.91
Molecular weight35846.31
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33589
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     376.73|      81|      81|      56|     136|       1
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    4-   82 (120.13/63.26)	QDKvlDNSLDYIL.SRVNDLKKALTDLLMKLEHHHETLNWPSVL.NSFALLS...G..qINTLNRHLKSDKTPVLKNLIILPLKLS
   83-  164 (156.13/83.98)	QDR..DEELEKVTEGRVASFNHDVVPNYLRTKPEPESEEREQVLAKDAAQLSPEVA..kINTLNRHLKSDKSPVKKNLIILPLKLS
  165-  227 (100.48/51.95)	QDR..DEELEKVTEGRVASFNHDVVPNYLRTKPEPESEEREQVLAKDAAQLSPEVAkkqIDNLNR.....................
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33589 with Med8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HDVVPNYLRTKPEPESEEREQVLAKDAAQLSPEVAKKQI
2) WDPDSSKLNITTSSPSDTNMLVGAVNMGRGFKRGMVQQPMSNMGAQMARQGDQHAPVGKIPSGIRTNIKSGGGHFNR
184
243
222
319










Molecular Recognition Features






MoRF SequenceStartStop




NANANA