<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33566

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMARSTMSSQDVVRTLSSLQPLLQDAIQKKRTSLEWEKPYTVQGPLTWQVFFNIGPAETPEPLPIPRLMIGHDKDWLSSSPFALYYWEKLMLEPYSSARDVAYIALVPENKYILRCATMFFKELTAVYEGCRLGRHAPIAKTFQDGIMKIGKKYAQKLSNEPVDVWFTDVAHLPEADKLKLYAQFCRAYVAPFLNQEQPDASMFRTSRHHSSSSGASSGSNVPGSGSYPSSSSSSSYVVGSSNTSGSQGGAMHEQGSQGSDTSSASMPAPSSTPSRPANRQDSKDGSSASSSENKENLPKVTALETVTPRDSEQPPAVVVYIVDPFRRGEDAEEEGEVSVATLGLMHCFAEIFDKLQVSLQRNIAFQIIPLHQVLQVANSEVSSRFLNQLKSVAFSVFSQCRRFQSPTIPGRSLTGFGPAADLDRTIITKNAEHNEDRLYAPPFILAPIKDKQTELGESFGGLRQACGELFCSYCLSHDQRWLLVSCTDSKGELMETQIINVDVQNSKRRKKVSVRNIALYCLWDFLMGVISKASIPWRLVIGRLGRLGQGELKDWSMLLSRKNLAHYSRKLREQCSMCSVPGTLDFPCILSACLVSTEPEPGLSIMADMVAADKCSKNSQRDQPSCQLHTPDDASCTHIMVFPTSATKQAAATNMPQDQADLTFNSELRLDDEDPFLVDDLLLNIFMNTSNMMPDPSNIQLSDLDQEPIPTDGGPAPAAQGPGNPTTRQQPNQEPGIPAEPEDVLRGILQQPLALGYFISTAKTGPLPKWFWSACPEAENSCPVFLKAALHVHNPSEQPDDILQTKHSHPLDSDRTPEVLRYVLETYNSLSWLTVDPSSGDRRSCLPVHMVVLVQLYNTIASLQ
Length864
PositionMiddle
OrganismStrongylocentrotus purpuratus (Purple sea urchin)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.344
Instability index60.32
Isoelectric point5.60
Molecular weight95381.92
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33566
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.48|      24|     139|     256|     281|       1
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  212-  229 (25.04/ 7.18)	SSGA.SSGSNVPGSGSYPS......
  231-  250 (27.35/11.43)	.....SSSSSYVVGSSNTSGSQGGA
  256-  280 (39.09/22.12)	SQGSdTSSASMPAPSSTPSRPANRQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.25|      52|     138|     641|     697|       2
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  641-  697 (81.27/70.14)	VFptsaTKQAAATNMPQDQADLTFNSELR..LD.DEDPFLVdDLLLNIFMNTSNMMPDPS
  784-  838 (81.98/55.60)	VF....LKAALHVHNPSEQPDDILQTKHShpLDsDRTPEVL.RYVLETYNSLSWLTVDPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.71|      41|     191|     396|     441|       5
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  396-  441 (65.00/47.61)	VFSQCRRFQSPTiPGRSLTGFGPAADldrtIITKNAEHNED..RLYAP
  589-  631 (68.71/37.88)	ILSACLVSTEPE.PGLSIMADMVAAD....KCSKNSQRDQPscQLHTP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     142.12|      42|     479|      47|      89|       6
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   47-   89 (80.92/64.43)	WQVFFN.IGPAETPEPLPIPRL.MIGHD..KDW...LSSSPFAlYYWEKL
  523-  571 (61.20/42.88)	WDFLMGvISKASIPWRLVIGRLgRLGQGelKDWsmlLSRKNLA.HYSRKL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33566 with Med13 domain of Kingdom Metazoa
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