<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33545

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMSGTPGGGVQTPAIPVPQGLPPLGLTMPGIQTPNPGPGGNMMGVAQAGGMQMVPMQPMAGGGGGGGGASISLGLLLEHLVQKTYHELTVLSELLPRKMDMEKKIEIVKFARSTRQSFIRLLALVKWAGSAAKVDKLPNFNLPHAVDVLTMRQYKRMPACIKERIVPPDPITSVEKETVLHRLDQIIQHRLVTSELPPQLANLTIEEGRVKFRVPQEFEVTLTLMEDNKTIPWRLLNIEILVQDPDTGDGKTLVHPIQVMCIHQLVQSRLFGDDKPLVDISQSLHASKKPELFKLTVSIDDDDVAKPLQVLHDPPLDMVDAAHVNQAIRVTLTLMEDNKTIPWRLLNIEILVQDPDTGDGKTLVHPIQSLQLEVLYSQVQRLISERWGEHVTIDKYTAGECLMMSYWRSQSLHASKKPELFKLTVSIDDDDVAKPLQVLHDPPLDMVDAAHVNQAIRCDHLSVERLLVETVLVRSRLKLKGLQEELEKDLPGCKCHVEGSPSLLYIPVVKPCSEDEQLMVSVDMQTGSYIPSIAHCGSTLLDEIDQGLNHERSKLEPLIAKLRVLLYMRHCQYSVSMLPVTFLKELPLVTVSPEHPVNRLLPNYIYLRLTQHPQYYVVVDFALGKGLGDFLCRYHLMRCSSASYIDAQTIPQGGAAPSAQKDTPETTEKYLHPDVFVDLDHSTILRGPDTSVEDLDVDDDEKKRKVSQIFTEYYIYKRMY
Length719
PositionTail
OrganismStrongylocentrotus purpuratus (Purple sea urchin)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-0.179
Instability index41.14
Isoelectric point5.78
Molecular weight80406.25
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33545
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     403.65|      73|     126|     280|     352|       1
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  197-  242 (74.54/43.14)	..................PQLANLT..IEEGRVKFR................VPQEFEVTLTLMEDNKTIPWRLLNIEILVQ
  280-  352 (144.46/90.60)	SQSL.........HASKKPELFKLTVSIDDDDVAKPLQVLHDPPLDMVDAAHVNQAIRVTLTLMEDNKTIPWRLLNIEILVQ
  408-  473 (123.22/76.18)	SQSL.........HASKKPELFKLTVSIDDDDVAKPLQVLHDPPLDMVDAAHVNQAIRC......DHLSVE.RLLVETVLVR
  482-  542 (61.42/34.23)	QEELekdlpgckcHVEGSPSLLYIPV.VKPCSEDEQLMV....SVDMQTGSYIPSIAHCGSTLLDE................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     124.44|      30|     109|     243|     272|       2
---------------------------------------------------------------------------
  141-  167 (20.81/ 6.80)	.........LPHAVDVLTMRQYkrmpacIKERIVPP
  243-  272 (59.83/30.33)	DPDTGDGKTLVHPIQVMCIHQL......VQSRLFGD
  353-  384 (43.79/20.66)	DPDTGDGKTLVHPIQSL...QLevlysqVQ.RLISE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.78|      11|      18|       8|      24|       3
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    8-   19 (19.07/18.90)	GVQTPAiPVPQG
   29-   39 (24.72/ 6.51)	GIQTPN.PGPGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.37|      10|     461|     117|     139|       4
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  106-  115 (16.94/13.39)	IVKFARSTRQ
  123-  132 (17.43/14.81)	LVKWAGSAAK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33545 with Med14 domain of Kingdom Metazoa
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