<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33537

Description Uncharacterized protein
SequenceMATLSLPSALPEQNGAMKAHHENGSDHDTVLPNLMQKLQMTTKQIKAWSQTSQKLRLAMSKYTDPDPVDPNRLKKCLDKLKMAIKVTSVPAMNERLDAIARQVGLKANWSIDNVYLSSDCFYVEVLLAPNGGVKDVILVHGMNGNLQSCEEMCDVLKKNDFKEFTEHLKGLCQMYQLGGDSKMKTTAFNCLQALEVDIKTLFHISGIKFGASQQQGGSPLLHITKGFVGYLTPRVGGHLMRLTYFVSPYDLLDVEKKQTKELSLKEPLPKDLGLSVTVSIETAAQRKIQTGPTVMVTDNKITNVMPLGNQNSITIPASFVLKLSEPMPMSLILLKQLQNISGVSTQYADPTAATPLNTLICKFTLDPVTFLQNQAKEGRSNKTKNYVVELPDQHHSYIINDGTNPNDLRDMQGALLSKITFTLPNTVVKIIALLRQQAVYNTLIASCVRSKDGQEPHEAVLFEVTPYTNQKLTVTFEHPAREGVACVELDLTDQSAVKAKLHSGPSEEPFCSDDYATRVLQKCLSIPITMRAIMKKAEQWLEMQESKKSVSLPPAPSSGPSGGSVFDPMSGLHRHTGLGGGGHGGTFFPSHRPHQSSYSHQLQSHSILSDLTTTMSAILPHGEGFDMHSDRPTKVAQNPMLASLLQHAALAVSTSSLSIPPPSSSPMSSPPLASGPKPHKNPMLMNLLQEHNTLTPVAAIAQPVGSMGRMIRRGKRGRSVSVDKSPKRQQSEEEHDFDDIHGHRPPGLHHRLSDTHGKMASHAMDPPKAMHTGELSALLSEIEAPIIPVAKPKRGRPCRLDSTSSQSSVGPRQSPKTPNTPTVPTTPTFAPPKTMSHSTLSTPEHPSMDDVPVGMKVDPLHSRTSMDSDIFSQNSKNIFSEDLLPDPPRSNISPEMHRQASFRSQYGSLDINDDAAGFDNDDDFGGLPSVSSAIARMGIPTGSEFDVQHRTTTDLPHPVSLSTLMSGPLSTAMQAGLETRTDMKMGVGALDLTVANLAKSMSIPAIPTTQRGRPGPNMQGVTNLSQSLPAARPRIPVSKGKPKNFIESSLAFQTEKPKPSKKRGRKPVKDSGGFSDSEAPKTKKLRKPGRLKKERRLPEYSSESSPEPCQDVARYSSITMAVNEEEPLKMTFKTIRHKPDRDQKLKGKDPGPAPKIKIRSMTSGDSATPSPNPVVREIKEEKPHMKPEHKVEQPEKVETTVQSVRTESPVMKSVKTESPVMKFDNPKETKVMRNESLPKLQKELSTGHRSEEQTNRGTSQELPKGSHDITGFKSEHLGVKSTGITKITAITHMPKVKNEQMKKSRPIESSQRPSPVSKSPIADFFPKKSLANLPRIPKISKQTSEGKQLLTPKTPTISKPAGSPSPSTKSLMGSSPKKSSWGKGDPSKVGSTKKLVTAQRFSSVSPTGRKPDGMRPGKPFSSGNKSPLTVGQGNRKPGLNIISKSLSTPTQSPNSSKASAGLIHAPNKNVSSPTTGVSKAISSQVRPSGTVSPVPKTLAGITSKAQTTPISLSAPSKLASSQAVPVSSSIKTSSVVPSTTTSSSGTSSGSSTKAISSSPVSMARLVPVASTSSTSSSSSVRSVSVANASSTSSSSSTTATTSVPTTPSITTTTSITSCATGSALPVSKSVTPPPVNLVPSSKSYPAITGIKTVSNRPPPLVIPTNIKVPAPSVTSPPTPSSVGTPTSAGPNSAKLTTPKPGMRANRKCSLMGIIDKIKEKNEKVDKTDKVEKVEKSEKTERKGLFSALGSGTPGVTESGNDDEKAIDATEKEAKETVPTDESGAEKPQMSKENKPVASSKADDYPTKESKSMTMPPTKSDTTKTPVPKVSSASSQLPARQPSPSLSTKPSGLTSSPSSQGPSSVKGKSSPKHPSQSRPPKVSTPPLTGSQKRSSSPTGKSISIKQSKPSPLTSSSSSTPTSMSSPVKARPGSSPMQRTRPIILSHSLSTYQSPEKGQQKVTKVQLAMQPDLMPHSTLPGQGTSASNVSKGQTGSSQVCVPSPSIKPQAVSINKPTQDPTKKSTTVTPKPTDTTKSDIKLVTTTPKPVKVDQSAIMKPKPNNGKEPSSQSQQNSQRSDAKGSSDNGSSKMPSMSSKKPDSKPTDPRARKDSLGSSKDKDGETSKSPKPAVVRSVSKESKISFGSGSQDGKTSTKPELKQTTESAQKVKVIPPLVKSVSQGDKEKLKGDEFRKSESKNIVPEIKGIDKQEVSEEINKISTSAKPQGIDFKVPSPAMVPSPKTSAVSPRPLIKPVGSPKPVVAYSPKAPSPHSSASGVPSPGSALSPKAPTKRSATPVGNQPPPPKKQCTISTPYSPVESDDDFGMIIDMPQSPRSISQQKSQRSPRPDSRNSNTQTEGGSTSPRSAVAHSPLGQLAQSPLGIGKSPASVKSIASSDSISRSPCKIDDDLMDEALTSCIQTEDV
Length2421
PositionMiddle
OrganismStrongylocentrotus purpuratus (Purple sea urchin)
KingdomMetazoa
Lineage
Aromaticity0.03
Grand average of hydropathy-0.638
Instability index58.09
Isoelectric point9.75
Molecular weight258190.44
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33537
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     341.11|      45|      47|    1504|    1548|       2
---------------------------------------------------------------------------
  803-  843 (52.05/11.83)	TSSQ..SSVG......P...R....QSPKTPNTP...T....VPTTPT.FAPPKTMS.HSTLSTP.
 1421- 1465 (40.95/ 7.46)	SSGNKSPLTVgqgnrkP...G....LNIIS...........KSLSTP..TQSPNSSK.ASAGLIHA
 1488- 1526 (50.67/11.29)	SGTV...SPV......P...K....TL...AGIT...S...KAQTTPI.SLSAPSKL.ASSQAVPV
 1527- 1568 (60.66/15.22)	SSSIKTSSVV......P...S....TTTSSSGTS...S...GSSTKAI.S.SSPVSM.A..RLVPV
 1839- 1886 (52.57/12.04)	RQPSPSLSTK......P...S.gltSSPSSQGPS...SvkgKSSPKHP.SQSRPPKV..STP..PL
 1887- 1933 (39.20/ 6.77)	TGSQKRSS.S......PtgkS....ISIKQSKPSpltS...SSSSTPT.SMSSPVKArPGSS....
 2268- 2311 (45.00/ 9.05)	PHS..SASGV......P...SpgsaLSPKA...P...T...KRSATPVgNQPPPPKK.QCTISTP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     165.93|      26|      27|    2063|    2088|       5
---------------------------------------------------------------------------
 1056- 1081 (26.64/ 7.39)	.KP..KPSKKRGRkpvKDSGGFS...D....SEAPK
 1369- 1394 (27.74/ 8.07)	KSLMGSSPKKS.......SWGKG...DpskvGSTKK
 2063- 2088 (41.26/16.46)	KEPSSQSQQNSQR...SDAKGSS...D....NGSSK
 2095- 2123 (39.20/15.19)	KKPDSKPTDPRAR...KDSLGSSkdkD....GETSK
 2131- 2152 (31.10/10.16)	RSVS....KESKI...SFGSGSQ...D....GKTST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     156.76|      39|      41|     604|     644|       6
---------------------------------------------------------------------------
  583-  602 (28.01/ 6.87)	.................HGGTF.FPSHRP....H...QSSYSHQL
  604-  644 (66.03/32.93)	SHSILSDLTTTMSaiLPHGEGFDMHSDRP....TKVAQNPMLASL
  646-  687 (62.72/26.66)	QHAALAVSTSSLS..IPPPSSSPMSSP.PlasgPKPHKNPMLMNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     168.18|      45|      45|    1136|    1180|       7
---------------------------------------------------------------------------
 1083- 1140 (37.77/11.78)	..KKL..RKPG...RLKKER..........RLPEYSSESS.PEPC.QDVARyssitmavneeeplkmtfktiRHKPD
 1141- 1192 (65.78/27.10)	RDQKLKGKDPGPAPKIKIRS..........MTSGDSATPS.PNPVVREIKE..............ekphmkpEHKVE
 1786- 1829 (32.86/ 9.09)	KPQ..MSKENKPVASSKADDyptkesksmtMPPTKSDTTKtPVPKV...............................
 2005- 2029 (31.77/ 8.50)	KPQAVSI..NKP.....TQD...........PTKKSTTVT.PKP.................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     280.68|      56|     502|    1206|    1276|       8
---------------------------------------------------------------------------
  999- 1039 (61.88/19.85)	............KSMSI.PAIPTTQRG.RPGPNMQGVTN..LSQSLPAARPRI.PVSK
 1218- 1269 (79.12/37.11)	SPVMKFDNPKETKVMRN.ESLPKLQKELSTGHRSEEQTNRGTSQELPKGSHDI.....
 1277- 1318 (50.02/17.02)	...LGVKSTGITKITAI.THMPKVKNEQMKKSRPIESSQRP............sPVSK
 1319- 1363 (62.80/20.32)	SPIADF.FPK..KSLANlPRIPKISKQTSEG..KQLLTPKTPTISKPAGS........
 2236- 2260 (26.85/ 7.56)	.............................PSPKTSAVSPRPL.I.KPVGSPK..PVVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.22|      37|     343|     544|     580|       9
---------------------------------------------------------------------------
  544-  580 (69.23/32.88)	QESKKSVS...LPPAPSS.......GPS..............GGSVFDPMSGLHRHTGLGG
  873-  926 (49.53/20.91)	QNSKNIFSedlLPDPPRS.......NISpemhrqasfrsqygSLDINDDAAGFDNDDDFGG
 1672- 1703 (25.46/ 6.29)	.....SVT...SPPTPSSvgtptsaGPN..............SAKLTTPKPGMR.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.54|      23|      41|    2338|    2361|      10
---------------------------------------------------------------------------
 2338- 2361 (37.69/16.61)	KSQrSP.....RPDSRNSNTQTEGGSTSP
 2373- 2400 (32.85/10.51)	LAQ.SPlgigkSPASVKSIASSDSISRSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.65|      26|      41|    1712|    1737|      11
---------------------------------------------------------------------------
 1712- 1737 (40.40/30.88)	GIIDKIKEKNEKVDKTDK..VEKVEKSE
 1754- 1781 (37.25/27.73)	GVTESGNDDEKAIDATEKeaKETVPTDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.69|      31|      42|     702|     733|      13
---------------------------------------------------------------------------
  702-  733 (49.30/29.45)	QPVGSMGRMIRRGKRGRSVSVDkSPKRQQSEE
  744-  774 (58.39/31.57)	RPPGLHHRLSDTHGKMASHAMD.PPKAMHTGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.25|      21|      25|    2167|    2191|      14
---------------------------------------------------------------------------
 2167- 2191 (26.10/27.16)	KVIPPLVKSVsqgDKEKLkGDEFRK
 2195- 2215 (35.15/20.68)	KNIVPEIKGI...DKQEV.SEEINK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.78|      21|     393|    1588|    1609|      15
---------------------------------------------------------------------------
 1588- 1609 (29.80/16.56)	ASSTSSSSSTTATTSVPtTPSI
 1984- 2004 (36.98/17.33)	ASNVSKGQTGSSQVCVP.SPSI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33537 with Med1 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATLSLPSALPEQNGAMKAHHENGSDHDTVLPN
2) AVSTSSLSIPPPSSSPMSSPPLASGPKPHKNPMLMNLLQEHNTLTPVAAIAQPVGSMGRMIRRGKRGRSVSVDKSPKRQQSEEEHDFDDIHGHRPPGLHHRLSDTHGKMASHAMDPPKAMHTGELSALLSEIEAPIIPVAKPKRGRPCRLDSTSSQSSVGPRQSPKTPNTPTVPTTPTFAPPKTMSHSTLSTPEHPSMDDVPVGMKVDPLHSRTSMDSDIFSQNSKNIFSEDLLPDPPRSNISPEMHRQASFRSQYGSLDINDDA
3) ILPHGEGFDMHSDRPTKVAQNPMLASLLQH
4) MGIPTGSEFDVQHRTTTDLPHPVSLSTLMSGPLSTAMQAGLETRTDMKM
5) MQESKKSVSLPPAPSSGPSGGSVFDPMSGLHRHTGLGGGGHGGTFFPSHRPHQS
6) SMSIPAIPTTQRGRPGPNMQGVTNLSQSLPAARPRIPVSKGKPKNFIESSLAFQTEKPKPSKKRGRKPVKDSGGFSDSEAPKTKKLRKPGRLKKERRLPEYSSESSPEPCQDVARYSSITMAVNEEEPLKMTFKTIRHKPDRDQKLKGKDPGPAPKIKIRSMTSGDSATPSPNPVVREIKEEKPHMKPEHKVEQPEKVETTVQSVRTESPVMKSVKTESPVMKFDNPKETKVMRNESLPKLQKELSTGHRSEEQTNRGTSQELPKGSHDITGFKSEHLGVKSTGITKITAITHMPKVKNEQMKKSRPIESSQRPSPVSKSPIADFFPKKSLANLPRIPKISKQTSEGKQLLTPKTPTISKPAGSPSPSTKSLMGSSPKKSSWGKGDPSKVGSTKKLVTAQRFSSVSPTGRKPDGMRPGKPFSSGNKSPLTVGQGNRKPGLNIISKSLSTPTQSPNSSKASAGLIHAPNKNVSSPTTGVSKAISSQVRPSGTVSPVPKTLAGITSKAQTTPISLSAPSKL
7) SQAVPVSSSIKTSSVVPSTTTSSSGTSSGSSTKAISSSPVSMARLVPVASTSSTSSSSSVRSVSVANASSTSSSSSTTATTSVPTTPSITTTTSITS
8) TGSALPVSKSVTPPPVNLVPSSKSYPAITGIKTVSNRPPPLVIPTNIKVPAPSVTSPPTPSSVGTPTSAGPNSAKLTTPKPGMRANRKCSLMGIIDKIKEKNEKVDKTDKVEKVEKSEKTERKGLFSALGSGTPGVTESGNDDEKAIDATEKEAKETVPTDESGAEKPQMSKENKPVASSKADDYPTKESKSMTMPPTKSDTTKTPVPKVSSASSQLPARQPSPSLSTKPSGLTSSPSSQGPSSVKGKSSPKHPSQSRPPKVSTPPLTGSQKRSSSPTGKSISIKQSKPSPLTSSSSSTPTSMSSPVKARPGSSPMQRTRPIILSHSLSTYQSPEKGQQKVTKVQLAMQPDLMPHSTLPGQGTSASNVSKGQTGSSQVCVPSPSIKPQAVSINKPTQDPTKKSTTVTPKPTDTTKSDIKLVTTTPKPVKVDQSAIMKPKPNNGKEPSSQSQQNSQRSDAKGSSDNGSSKMPSMSSKKPDSKPTDPRARKDSLGSSKDKDGETSKSPKPAVVRSVSKESKISFGSGSQDGKTSTKPELKQTTESAQKVKVIPPLVKSVSQGDKEKLKGDEFRKSESKNIVPEIKGIDKQEVSEEINKISTSAKPQGIDFKVPSPAMVPSPKTSAVSPRPLIKPVGSPKPVVAYSPKAPSPHSSASGVPSPGSALSPKAPTKRSATPVGNQPPPPKKQCTISTPYSPVESDDDFGMIIDMPQSPRSISQQKSQRSPRPDSRNSNTQTEGGSTSPRSAVAHSPLGQLAQSPLGIGKSPASVKSIASSDSISRSPCKID
2
651
618
937
543
1000
1521
1620
33
915
647
985
596
1518
1617
2404










Molecular Recognition Features






MoRF SequenceStartStop




1) ANRKCSLMGI
2) IDFKVP
3) KKRGRK
4) KLVTA
5) KSDIKLVTTTPKPVKVDQSAI
6) LKMTFKTIRHKPDRDQKLKGKDPGPAPKIKIRSMTSGDS
7) PKTSAVSPRPLIKPVGS
8) PVVREIKE
9) QMKKSRPI
10) QRTRPIILSHSLSTYQS
11) SEAPKTKKLRKPGRLKKERRLPEYSSE
12) VSKESKISF
13) VSKSPIADFFPKKSLANLPRIPKISKQTSEGKQLLTP
14) YPAITGIK
15) YSPVESDDDFGMIIDM
1704
2225
1061
1394
2034
1128
2238
1173
1300
1936
1077
2133
1316
1644
2312
1713
2230
1066
1398
2054
1166
2254
1180
1307
1952
1103
2141
1352
1651
2327