<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33518

Description Uncharacterized protein
SequenceMDKTFVEEEFMMAGMGGTNGSNSNMFGAFSMPPNNGMGNGGGLNMPMNMGAMQSMMYMGVPQMASMYNPSASNSVDELGSAAIEFPPELGGDPPKLTASSSLNSGGAMDPSAMMGMNSMMATGMNPHMYLNPGMQQMQYNPMFGGYPPQNLNMMQQQHQMMQQQQYLQFMQQNMINMNNNQQGGNNSNPGTSTSNNNMMANPTPQATPPPPAAPPSASSGATTNAGGSWRSPSDDPQRKDVIGRIIRFLQMQKPNAPPDWIRRLPQMARKLEEALYRKASSKPEYNDMNTLQQRLHVVAQEFKNKDWRSADDNGIRQDLIHRIVMLLRAQNPNATPDWINRLPHMAKKLEEMLYQKATSKAEYTDNARLKERLQVVATEIHKNNQKKAAKVPPDAPTTASALKMEALGMPAELRHPFLDIARAIASYLTPRTITEYNHKVLTMIQNIGQHRVVLMRQQQRLMQLKHACECHADKCAHPACAEMKPLWAHIQTCPESENCATPHCVSSKYVLAHYQQCMKSTCVVCASLNQPPPPQQQQQQQLNHLQQQQQQQMLQHHHQLQQFKQQQQQQHQAVLAQQNQPLQMPRELKDELQVSPFASHAKLISSTLPENIIRDYHQKVDFMMNDSSQAQHQSILHRQQQRLLELRHASECKADKCAHPACAEMKPLWTHVVTCRQADTCPTPHCVSSKYVLAHYQHCMKPHCVVCLPLRDVKKTDGGGGGTADKIRQFTDKAKGAANMLTTRQIQDYHAKVLGMMHVKCVAQNQTILERQQQRLLHLRHALFCPADKCAAAYCAEMKKLWSHVMGCKKSESCAYAHCLSSKYVLSHFQQCTNPACVVCALVRDAHEMEKAMAEDARANMDKKDQPLAPANQPVKRGLESTETNQQPPSKKQALAVPSPPESCGTRSAKADNSQQQHSMIACPPELLKDEPDVLKDDEFAFMQDIDEELGGEVLEFDEW
Length960
PositionTail
OrganismAphanomyces astaci
KingdomOomycetes
LineageEukaryota> Sar> Stramenopiles> Oomycota> Saprolegniales> Saprolegniaceae> Aphanomyces.
Aromaticity0.05
Grand average of hydropathy-0.665
Instability index55.12
Isoelectric point8.27
Molecular weight107610.00
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33518
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|    1009.09|     178|     179|     409|     587|       1
---------------------------------------------------------------------------
  225-  408 (179.25/76.53)	AGGSWR.SPSDDPQR...KDVIGRII.....RFLQM..QKpNAPP..DWIRRLPQMAR..KLEEALYRKAS..SKPEYNDMNTLQQRL............HVVAQEFKNKDWRSAddngIRQDLIhrIVMLLrAQN......................PNATPDWINRLPHMAKKLE....EML.......yqkatskaeytdnarlkerlqvvateiHKNNQKKAAKVPPDAPTTASALKMEAL....G
  409-  587 (334.68/152.30)	MPAELR.HPFLDIARAIASYLTPRTITEYNHKVLTM..IQ.NIGQ..HRVVLMRQQQRLMQLKHACECHADKCAHPACAEMKPLWAHIQTCPESENCATPHCVSSKYVLAHYQQC....MKSTCV..VCASL.NQP......................PPPQQQQQQQLNHLQQQQQ....QQML.....Q...........................HHHQLQQFKQQQQQQHQAVLAQQNQPLqMPRE
  588-  712 (227.65/99.25)	LKDELQvSPFASHAKLISSTLPENIIRDYHQKVDFM..MN.DSSQaqHQSILHRQQQRLLELRHASECKADKCAHPACAEMKPLWTHVVTCRQADTCPTPHCVSSKYVLAHYQHC....MKPHCV..VCL.................................................................................................................PL...RD
  723-  926 (267.50/117.95)	TADKIR.Q.FTDKAKGAANMLTTRQIQDYHAKVLGMmhVK.CVAQ..NQTILERQQQRLLHLRHALFCPADKCAAAYCAEMKKLWSHVMGCKKSESCAYAHCLSSKYVLSHFQQC....TNPACV..VCALV.RDAhemekamaedaranmdkkdqplAPANQPVKRGLESTETNQQppskKQALavpspP...........................ESCGTRSAKADNSQQQHSMIA.......CPPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.68|      16|      21|      14|      31|       2
---------------------------------------------------------------------------
   14-   29 (33.04/14.23)	GMGGTNGSNSNM.FGAF
   36-   52 (26.63/12.04)	GMGNGGGLNMPMnMGAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.29|      13|      15|     106|     119|       3
---------------------------------------------------------------------------
  106-  119 (21.62/14.24)	GaMDPSAMM..GMNSM
  123-  137 (20.66/ 8.59)	G.MNPHMYLnpGMQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.30|      21|      22|     138|     158|       4
---------------------------------------------------------------------------
  138-  158 (44.34/21.41)	QYNPMFGGYPPQNL.NMMQQQH
  165-  182 (23.36/ 7.73)	QY....LQFMQQNMiNMNNNQQ
  183-  199 (21.59/ 6.57)	GGNNSNPGTSTSNN.NMM....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.53|      15|      25|      61|      80|       6
---------------------------------------------------------------------------
   61-   80 (18.06/24.82)	PQMASmyNP...SASNSvdeLGS
   87-  104 (22.47/11.46)	PELGG..DPpklTASSS...LNS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33518 with Med15 domain of Kingdom Oomycetes


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DELGSAAIEFPPELGGDPPKLTASSSLNSGGAMD
2) GGYPPQNLNMMQQQHQMMQQQQYLQFMQQNMINMNNNQQGGNNSNPGTSTSNNNMMANPTPQATPPPPAAPPSASSGATTNAGGSWRSPSDDPQRKDVIGRIIRFL
3) KAMAEDARANMDKKDQPLAPANQPVKRGLESTETNQQPPSKKQALAVPSPPESCGTRSAKADNSQQQHSMIACPPELLKD
4) LEEALYRKASSKPEYNDMNTLQQRLHVVAQEFKN
5) MLQHHHQLQQFKQQQQQQHQAVLAQQNQPLQMPRELKDE
6) QVVATEIHKNNQKKAAKVPPDAPTTASALKME
76
144
851
271
553
374
109
249
930
304
591
405










Molecular Recognition Features






MoRF SequenceStartStop




1) FAFMQDI
2) GRIIRFLQ
3) LEFDEW
940
243
955
946
250
960