<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33501
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MGSTDIPLDEIQWHHPQLADSMQGIHSNSVLFYFAESPFFDKTSNNAVIANQAMFNPAMYQYIQTREAFEGRLKTMSGVEFIVAEQPAQMAPGTGTGVWVIRKQTRRKRPGEEDEIIVHSSYYVVGYNIYMAPTLADILSFRMATITNSLRKCFPAADEARTWSPAQGHAYKPQPATTNSRERQLAASKEATPLPDSQAAAGKPSEPKKSAQSSILDARLAEHSFAVQMQYGGEYMDENPITGHPGSFHLSSTGRKERPRAPTLNPLTTNLKNPVSTKAVDKKDGTKEAKTPKTPNSGISKPKRKKTKTGLTPGATPS |
Length | 318 |
Position | Head |
Organism | Pestalotiopsis fici (strain W106-1 / CGMCC3.15140) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Xylariomycetidae> Xylariales> Sporocadaceae> Pestalotiopsis.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.663 |
Instability index | 40.75 |
Isoelectric point | 9.45 |
Molecular weight | 34912.00 |
Publications | PubMed=25623211
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP33501
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
4| 208.32| 46| 127| 132| 178| 1
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132- 176 (73.41/45.50) APTLADILS.FRMATITNSLRKCFPAADEART.WSPAQGHAYKP.QPA.
178- 207 (24.94/10.93) ................TNSRERQLAASKEATP.LPDSQAAAGKPsEP..
213- 252 (54.28/33.74) ....SSILD.ARLAE..HSFAVQMQYGGEYMD.ENPITGHPGSF.HLSS
261- 306 (55.69/31.43) APTLNPLTTnLKNPVSTKAVDKK.DGTKEAKTpKTPNSG.ISKP.KRKK
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