<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33498

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMAASFWESTQRRFWIFTKDELARTRNKLREDEQALVAMFPLPEWRHLSIYFNQQVTRLAKRLVLRQQVVATAQVYLKRFYTKVEVRRTNPYLLCVTALYLACKMEESPQHIRLVVQEARSLWPDFLTLDMSRLGECEFFLISEMNAQMIIHQPYRTLTTLQSDFFLSSDEISLSWTIINDHYMTDLPLLYSPHIIALTAILLSLVLRPNPVAGGQAASMAAAQAVLAQAQTQSQSQMQAQGSRGLGSGLSSGQTTPGGAFEKDNKSNEARVGKLQRFGAFLAESDVAIEDMVGCTQELIAFYEVHEQYNEKAVRDQINRFIKARGLDKG
Length329
PositionKinase
OrganismPestalotiopsis fici (strain W106-1 / CGMCC3.15140)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Xylariomycetidae> Xylariales> Sporocadaceae> Pestalotiopsis.
Aromaticity0.09
Grand average of hydropathy-0.181
Instability index54.54
Isoelectric point7.69
Molecular weight37409.48
Publications
PubMed=25623211

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33498
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.00|      24|      25|     137|     160|       1
---------------------------------------------------------------------------
  137-  160 (44.68/29.55)	EFFLIS.EMN.AQMIIHQPYRT.LTTL
  163-  189 (32.32/19.74)	DFFLSSdEISlSWTIINDHYMTdLPLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.43|      18|      18|     258|     275|       2
---------------------------------------------------------------------------
  258-  275 (30.75/23.92)	GAF.EKDNKSNEARVGKLQ
  278-  296 (27.68/20.87)	GAFlAESDVAIEDMVGCTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.01|      12|     140|      62|      73|       3
---------------------------------------------------------------------------
   62-   73 (20.24/12.52)	LVLRQQVVATAQ
  204-  215 (22.77/14.85)	LVLRPNPVAGGQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33498 with CycC domain of Kingdom Fungi
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