Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MSQSPPNPPAEDEPLYGGFSRFEVELEFVQSLANPFYLNHLASQKLLSDPAFIEYLKYLQYWNQPPYLRYLTYPGPTLKHLELLQQERFRQEIISPELVQVLASEGQKASIDWHREEKE |
Length | 119 |
Position | Middle |
Organism | Pestalotiopsis fici (strain W106-1 / CGMCC3.15140) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Xylariomycetidae> Xylariales> Sporocadaceae> Pestalotiopsis. |
Aromaticity | 0.13 |
Grand average of hydropathy | -0.612 |
Instability index | 73.60 |
Isoelectric point | 4.93 |
Molecular weight | 14012.62 |
Publications | PubMed=25623211 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi mediator complex GO:0016592 IEA:EnsemblFungi |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | DNA repair GO:0006281 IEA:EnsemblFungi meiotic gene conversion GO:0006311 IEA:EnsemblFungi meiotic sister chromatid segregation GO:0045144 IEA:EnsemblFungi regulation of transcription, DNA-templated GO:0006355 IEA:InterPro transcription by RNA polymerase II GO:0006366 IEA:EnsemblFungi |
Binary Interactions |
Repeats | >MDP33496 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) AEDEPLYGGFSRFEV 2) EYLKYLQYWNQPPYLRYLTYPG | 10 54 | 24 75 |
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