<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33493
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADDGESKNAITSTFPAPPPFWKDFTPDNVARITDLRQEQVEREGIADPSTVRLSGLPDNLRNLQPPSEPASGAWRVFGQNYALQEELPSLDNGTGIRKLFPEPEERDQDGKHFDRATILKRLAKSLLLNFLELTGILSSNPGAAEDKITDIRDLFLNFHHLINEYRPHQARESLISMMQAQLDRTRAETNAIRDVKEKVERMLEGLGSLKMEDTSSGAGEAKHIIGNHDLMLDSVLDVELA |
Length | 242 |
Position | Middle |
Organism | Pestalotiopsis fici (strain W106-1 / CGMCC3.15140) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Xylariomycetidae> Xylariales> Sporocadaceae> Pestalotiopsis.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.571 |
Instability index | 38.11 |
Isoelectric point | 4.94 |
Molecular weight | 27067.07 |
Publications | PubMed=25623211
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060
ECO:0000256 ARBA:ARBA00003669
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP33493
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 89.54| 20| 22| 61| 80| 1
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36- 57 (24.04/13.87) LRQEQVEREGIAdpSTVRLSGL
61- 80 (35.12/23.31) LRNLQPPSEPAS..GAWRVFGQ
84- 103 (30.38/19.26) LQEELPSLDNGT..GIRKLFPE
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