<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33490

Description Uncharacterized protein
SequenceMPPKKKLKGSAAPPRAPRRPRASQAIRPHFNTHTTTNGSQFTVHYYLPADPAVPIVRADPERTYNIVGDGETSRTTIFVTLRVPPDKYRHLHRSWSRPIETALPLTPATSFLTLTYRKPTAAREPPQINDAAKGTTNADLDDSAIDVGTPVAGFLDSPGRSAEPGTGVVVPPEPGGHFQPSVGTSSIESPAASAQQRNAVSDSLRPLTLRDQSGVTAKSPFGRSTPTAAINPLQARAAEARKHSAVDSSEGSGHSSTSPVGLRPSGRVGQWSGLQFQQQTQPLGRKVPTNPVLFERQSALVAKPAHSPLIQAQGLTNVDADHQVTTLDLLDSLPSRTSHHDTGTHIASGSEEADVGKTNVPDGRAGEANQRGCPLLASEHPPRPRPLSAFTPVSGLPRRLVVKLKLPIGYTLNENMAPTRDPSDVSGVIKDIVDDLYDVQSKTHGFIPETQNLLIDKIGDMAEKLATLKDLTDPQINPNNPIHDVRIAPEIVDYVDDGRNPDIFTREFVENVQRGNSVINGKKQAFRDFSVIFAKALKQGIGGVDKHVDQIMENAGLEQELDEAMKKDKSKGTENGAE
Length578
PositionMiddle
OrganismCyphellophora europaea CBS 101466
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Cyphellophoraceae> Cyphellophora.
Aromaticity0.04
Grand average of hydropathy-0.576
Instability index40.41
Isoelectric point7.33
Molecular weight62252.92
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33490
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     343.64|      97|     105|     190|     293|       1
---------------------------------------------------------------------------
  119-  185 (52.50/15.78)	.................................PTAAREPPQINDA...AKGTTNADLDDSAIDVGTPVAGFLDSpGRSAEpGTGVVVPPEPgghfQPsVGTS.......
  194-  292 (154.27/70.71)	AQQRNAVS.DSLRPLtLRDQsGVTAKSPFGRSTPTAAINPLQARAA..EARKHSAVDSSEGSGHSSTSPVGLRPS.GRVGQ.WSGLQFQQQT....QP.LGRKVPT.NPV
  295-  393 (136.87/49.56)	ERQSALVAkPAHSPL.IQAQ.GLTNVDADHQVTTLDLLDSLPSRTShhDTGTHIASGSEEADVGKTNVPDG.R.A.GEANQ.RGCPLLASEH....PP.RPRPLSAfTPV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33490 with Med10 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ADHQVTTLDLLDSLPSRTSHHDTGTHIASGSEEADVGKTNVPDGRAGEANQRGCPLLASEHPPRPRPLSAFTP
2) LTYRKPTAAREPPQINDAAKGTTNADLDDSAIDVGTPVAGFLDSPGRSAEPGTGVVVPPEPGGHFQPSVGTSSIESPAASAQQRNAVSDSLRPLTLRDQSGVTAKSPFGRSTPTAAINPLQARAAEARKHSAVDSSEGSGHSSTSPVGLRPSGRVGQWSGLQFQQQTQPLGRKVPTNPVLFERQSALV
3) MPPKKKLKGSAAPPRAPRRPRASQAIRPHFNTHT
320
114
1
392
301
34










Molecular Recognition Features






MoRF SequenceStartStop




1) FLTLTYRK
2) FTVHYYL
3) MPPKKKLKGSAAPPRAPRRPR
111
41
1
118
47
21