<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33472

Description Uncharacterized protein
SequenceMSRPGSTLSHGIAQQLRKSTSALFEDSNKSQDKKPSGNTYVAKVRIGHKYDIVGFISSGTYGRVYKARERNPKGDTSSPTTNGPKELYAIKKFKPEKEGDNIQYTGLSQSAIREMALCTELSHPNVVHLAEIILEDKCVFMVFEYCEHDLLQIIHHHTQPTRRPIPASMIKSILFQLLNGLFYLHQNWVIHRDLKPANIMVTSSGHVRIGDLGLARLFHKPLSSLYSGDKVVVTIWYRSPDLLLGARHYTPAIDMWAVGCIFAELLSLRPIFKGEETKMDSKKTVPFQRNQMSKIIEILGMPRREHWKGLADMPEYPQLQSLMVGRGGIHGTGSLYPSHAGGVPNRAAGAATPGGDRGSNLETWYTNCIRAANYPTGKSPGQRGLKLLTDLFEYDPEKRLTAEASLKHEYFVCTDENSRHNGEVWVTNNCFEGLEESYPARRVSTETNDIGTGSLPGTKRGGLPDDSLLPPAKRR
Length475
PositionKinase
OrganismCyphellophora europaea CBS 101466
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Cyphellophoraceae> Cyphellophora.
Aromaticity0.08
Grand average of hydropathy-0.482
Instability index45.57
Isoelectric point9.15
Molecular weight53001.83
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP33472
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     189.60|      41|     119|     305|     345|       1
---------------------------------------------------------------------------
  305-  345 (75.98/55.99)	EHWKGLADMPEYPQLQSLMVGRGGIHG...TGSLYPSHAGGVPN
  383-  424 (50.96/34.71)	RGLKLLTDLFEYDPEKRLTAEASLKHEyfvCTDENSRHNGEV..
  429-  465 (62.66/44.66)	NCFEGLEE..SYPA.RRVSTETNDI.G...TGSLPGTKRGGLPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.27|      12|     107|     245|     261|       3
---------------------------------------------------------------------------
  250-  261 (23.64/11.03)	TPAIDMWAVGCI
  358-  369 (23.63/14.27)	GSNLETWYTNCI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP33472 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MSRPGSTLSHGIAQQLRKSTSALFEDSNKSQDKKPSGN
2) RRVSTETNDIGTGSLPGTKRGGLPDDSLLPPAKRR
1
441
38
475

Molecular Recognition Features

MoRF SequenceStartStop
1) PKELYAIKKF
2) STSALF
3) TKRGGLPDDSLLPPAKRR
4) TLSHGIAQQL
84
19
458
7
93
24
475
16