<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33456

Description Serine/threonine-protein kinase SSN3
SequenceMENYRQYPYASAGQPMRVASTDFFTIGPYRRRRDQARVSVVQKYEILGYIAAGTYGKVYKARGKTKELGNGLYAIKKFKTDSKDNEVTHYTGISQSAIREMSLCKELEHKNISRLIEIILERKCIYMVFEFAEHDLLQIIHYHSQPDHKQIPEQTLKSAMYQILEGLSFLHQNWVLHRDLKPANIMVTNDGVVKIGDLGLARKFSNPLQSLYSGDKVVVTIWYRAPELLLGARHYTPAIDLWAVGCILAELLSLRPLFKGEETKMDNKKQVPFQENQVIKILEILGTPTLDKWPSLNSYPEYPHLSKISTFPSNLKAWYQSNGGSNKNCLRLLASLLEYDPAKRIDALESLDHKWFQEAPKPVDNIFANSPFKYPQRKIQKDDNDILGGTSQTYYNGKRAFGAYEDPRKRR
Length411
PositionKinase
OrganismOgataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1) (Yeast) (Hansenula polymorpha)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Pichiaceae> Ogataea.
Aromaticity0.11
Grand average of hydropathy-0.518
Instability index49.99
Isoelectric point9.28
Molecular weight47317.70
Publications
PubMed=24279325

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:UniProtKB-EC

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33456
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     315.22|      97|     214|      71|     168|       1
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   71-  168 (159.67/105.94)	GLYAIKKFKTDSKDNEVTHYTGIS..QSAIREMSLCKELEHKNISRLIEIILERKCIYMV..FEFAEHDLLQ.....IIHYHSQPDHKqIPEQTLKSAMYQILEGLS
  286-  391 (155.55/98.91)	GTPTLDKWPSLNSYPEYPHLSKIStfPSNLKAWYQSNGGSNKNCLRLLASLLEYDPAKRIdaLESLDHKWFQeapkpVDNIFANSPFK.YPQRKIQKDDNDILGGTS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33456 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) DILGGTSQTYYNGKRAFGAYEDPRKRR
2) NYRQYPY
3) SPFKYPQRKI
385
3
370
411
9
379