<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33443

Description Uncharacterized protein
SequenceMNNQGFVPNSRPPIGAAAGGNQITQQDRVQFVNFIVASIAKIQGTNFSLQRTKPVAEEYEKFAFSNSSNKREYVDYLKSKIASINQSRQNAMQRQQQQQQQQTQQTQQPQQAQPQMARPTSQPQKIDIQNIPIPPSLLAKLPPLFPQGYNTWAMIMPFFRQKQMSPHDMQLIKEVYTMHTQLIRAKQQQEFSQMHNAMPGAQVNQGMSAGKQNAPNPQQVLMLQRQQQMKQSMMQQQQPMVTQQQQQQQQPQQPQQPQQPQQPQQPTGMRPAITPEQLESYKNQALQVIKNLQASNKLPPNLTPEQENTYVKRYLFHLLNNARQQPKVPVTQNGMPVQNQVVPQSRPQQNVPINKQQIPIQQQQNMMMQMQQNHMKAASQGQFNPMSAQSQPALQAMPQSQPQQLPTNQNQNGRTSQSGQQFGNRMPGQPLPQGQKPAMQPGGTGPRLFTGVQATEEDWRRLKAIYQEVAATPINLKDLTDEISEQEKQQIIKTIKQSQQLVLISETIIIPNFYMMTKSYEGTKKLMYSQLMIKQVLERLKNGGRFYANYDLLTKVQTQITRFLAYVKEQNSKMLKGQQQQHSVSVPNAMSQPGMVPPQNRYMMQQQPGMNMSTSASPIMPRVNTPQQQFMQHPSMNMNAGPVPQQFQQLSEQRQMPMMGQGAVSGKIPPQFIPGPPGGMIPNQQPTSAPVVAAAKKQPVRKKPVKPAASSAPTPKNKTIPLTQPGAVPASIGLSSAPSGSAANGALSPEVQSIMKEATEMIGKEESKLRAIDQQRNRRRELASVDPARYVLAVLADTLNLPEEESKIFEMAKSSSSKSRTLSSNAAQGNKVLTPSAILTTPLPFNVKTPTSFKYYGSAITPASYKGGHWQGKVNATVIAGVFKEVFSMIPKERRESSRNNLGTGLLGDLSSSVYPTPPDEEIQGKRKIEDVEIERKKVKVSSGPNDLDDLDNLWNFDGW
Length960
PositionTail
OrganismOgataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1) (Yeast) (Hansenula polymorpha)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Pichiaceae> Ogataea.
Aromaticity0.05
Grand average of hydropathy-0.786
Instability index66.46
Isoelectric point9.97
Molecular weight107420.33
Publications
PubMed=24279325

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33443
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.07|      22|      22|     218|     239|       1
---------------------------------------------------------------------------
  213-  236 (31.28/ 6.35)	NAPnpQQVLMLQRQQQMKQSMMQQ
  237-  254 (33.35/ 7.30)	QQP.....MVTQQQQQQQQPQ.QP
  255-  276 (35.43/ 8.25)	QQP..QQPQQPQQPTGMRPAITPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.50|      17|      22|     628|     647|       2
---------------------------------------------------------------------------
  591-  608 (22.92/ 7.72)	SQP.GMVPPQ.....NRyMMQQQP
  637-  659 (21.58/ 9.05)	NMNaGPVPQQfqqlsEQ.RQMPMM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.03|      22|      22|      98|     119|       4
---------------------------------------------------------------------------
  101-  122 (40.20/10.85)	QQTQQTQQPQQAQPQMARPTSQ
  419-  440 (37.82/ 9.78)	GQQFGNRMPGQPLPQGQKPAMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     192.57|      41|     239|     660|     704|       5
---------------------------------------------------------------------------
  347-  374 (38.88/13.00)	.........PQQNV.PINKQQ.IPIQQQQNMMM.......QMQQNH
  375-  406 (37.86/11.50)	MKAASQGQFNPMSAqSQPALQAMPQSQPQQLP..............
  660-  704 (65.02/34.72)	GQGAVSGKIPPQFI.PGPPGGMIPNQQPTSAPVvaaaKKQPVRKKP
  706-  738 (50.80/19.86)	KPAASSA........PTPKNKTIPLTQPGAVP.....ASIGLSSAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.05|      15|      15|     178|     192|       9
---------------------------------------------------------------------------
  178-  192 (26.33/13.52)	MHTQLIRAKQQQEFS
  194-  208 (27.72/14.67)	MHNAMPGAQVNQGMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.21|      34|     287|     464|     584|      10
---------------------------------------------------------------------------
  287-  320 (60.77/12.00)	QVIKNLQASNKL........PPN...LTPEQENT........YVKRYLFHLLN
  490-  542 (39.44/97.54)	QIIKTIKQSQQLvlisetiiIPNfymMTKSYEGTkklmysqlMIKQVLERLKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.55|      35|      73|     808|     842|      14
---------------------------------------------------------------------------
  808-  842 (57.21/40.18)	IFEMAKSSSSKSRTLSSNAAQGNKVL..TPSAILTTP
  882-  918 (55.33/38.59)	VFKEVFSMIPKERRESSRNNLGTGLLgdLSSSVYPTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.00|      23|     288|     146|     168|      15
---------------------------------------------------------------------------
  123-  145 (39.94/20.41)	PQKIDIQNIPIPPSLLAKLPPLF
  146-  168 (45.06/24.00)	PQGYNTWAMIMPFFRQKQMSPHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      60.98|      12|     388|     466|     477|      16
---------------------------------------------------------------------------
  449-  460 (19.59/11.48)	FTGVQATEEDWR
  466-  477 (19.93/11.82)	YQEVAATPINLK
  855-  866 (21.47/13.38)	YYGSAITPASYK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33443 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KGQQQQHSVSVPNAMSQPGMVPPQNRYMMQQQPGMNMSTSASPIMPRVNTPQQQFMQHPSMNMNAGPVPQQFQQLSEQRQMPMMGQGAVSGKIPPQFIPGPPGGMIPNQQPTSAPVVAAAKKQPVRKKPVKPAASSAPTPKNKTIPLTQPGAVPASIGLSSAPSGSAANGALSPEVQSIMKEATE
2) LIRAKQQQEFSQMHNAMPGAQVNQGMSAGKQNAPNPQQVLMLQRQQQMKQSMMQQQQPMVTQQQQQQQQPQQPQQPQQPQQPQQPTGMRPAITPEQLESYKNQALQVIKNLQASNKLPPNLTPEQENTYVKRYLFHLLNNARQQPKVPVTQNGMPVQNQVVPQSRPQQNVPINKQQIPIQQQQNMMMQMQQNHMKAASQGQFNPMSAQSQPALQAMPQSQPQQLPTNQNQNGRTSQSGQQFGNRMPGQPLPQGQKPAMQPGGTGPRLFTGVQ
3) NQSRQNAMQRQQQQQQQQTQQTQQPQQAQPQMARPTSQPQKIDIQNIPI
576
182
85
760
453
133










Molecular Recognition Features






MoRF SequenceStartStop




1) AAKKQPVRKKPVK
2) NFDGW
694
956
706
960