<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33407

Description Uncharacterized protein
SequenceMMIAPLSKGWPRLGLWRAYAWRRTRENSRGKGPVPKGSFPEINWLHHANRVENFSCQDKHLISNFQYSLPNQNPFSEGKQPQRSMPCVVQRPETLPNMFQVKKNFDAVTRLLVKCKGYLRPGITAPVVQSRVSDTTASKKSYFTEDHQKTNSLCNSSYDYPNVASEEMKTRAPNLTGTMMAGVSQQHQRNLSSHVVASMDGRSISHVSDSLLGTEMSSTRTVMDKREFGHVDAEVTSTVTPGKPNMHVPPCNEFGETIFDAIDDDEILKSIDVDQIVLKHYEATGTPQPSLSNISPVSPVGNKGNIRYPNGCPPPPELNTKCNHNFEVSLCPKAALHLQEMKDRLITVSNELLDNATNLIPENSEKLRQERLQLNKQIQHLEKYLRCSGGDEERQRSHSLASTSTAGVFNPQTPHNVKMSNSYTIDPPRFDSPWCNPSPMPFFSVERSFDQSRYVERELFTRKFVEVNYTDGSCDSRWSLTSFPWTKKLEVNNKKVFGNHSFRPNQREVINATMSGHDVFVMMPTGGGKSLTYQLPALISPGITLVVSPLVSLIQDQIMHLLQANISAAYLSANMDWSEQQQIFRELASGCCTYKLLYVTPEKIAKSDVLLRHLADLHNRELLARIVVDEAHCVSQWGHDFRPDYQGLGILKQKFPTVPVLALTATATASVREDVVQALGLVNCVVFYQSFNRPNLRYFIIPKTKRCLEDIDKFIRDYHHDECGIVYCLSKIDCEKVAERLQELGHKAAFYHGSMEPQQRAYVQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGLQSSCVLYYSYSDYMRVKHMLVQGASEQNSSTYGSGRAPAINSGRILEANIENLLRMVSYCENDVDCRRLLQLAHFGEKFDPMNCRKTCDNCCKNITYIEKNVTDIAKQLVELVKSTGQRFSSAHILEVYRGSLSQQVKRYKHELLSLHGAGKPLSKGDASRILRHMVTEDFLVEDVKKSDTYGSVSSVLKVKEAKVQGILFGNCKITLRFAVPQKANKPEKPEVTPAKGQLQLGKTPKIYDSPTQPQSEADPKLSALLFSALRTLRTMLVKEAGEGVMAYHIFGNATLQEISERVPRTKEELLEISGIGKAKIKKYGDRLLETIESTLKEYHKSEKNVSGNYENIESYKRRRETSVTPTTNPLPNDDFFEDVSLSKKRVTDVDKNEIRDKFSSVAAEKWDMDCRDAGNKCVIDLDDSEMTDDHHGQGGRILPTWLNPKSKPGGSTSPLFEDYAFRSQT
Length1275
PositionUnknown
OrganismAmborella trichopoda
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Amborellales> Amborellaceae> Amborella.
Aromaticity0.08
Grand average of hydropathy-0.528
Instability index50.17
Isoelectric point8.53
Molecular weight143815.84
Publications
PubMed=24357323

Function

Annotated function
	RuleBase:RU364150
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central
plasmodesma	GO:0009506	IEA:EnsemblPlants
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
cellular response to abscisic acid stimulus	GO:0071215	IEA:EnsemblPlants
cellular response to cold	GO:0070417	IEA:EnsemblPlants
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP33407
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.22|      21|      22|     187|     207|       1
---------------------------------------------------------------------------
  180-  192 (15.37/ 6.22)	......MAG..VSQQHQRNLS
  193-  213 (35.52/24.64)	SHVVASMDGRSISHVSDSLLG
  217-  231 (19.34/ 9.85)	SSTRTVMDKREFGHV......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.72|      21|      23|    1101|    1121|       2
---------------------------------------------------------------------------
 1101- 1121 (33.50/21.10)	GNATLQEISERVPRTKEELLE
 1126- 1146 (33.22/20.86)	GKAKIKKYGDRLLETIESTLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.79|      36|     160|     456|     495|       3
---------------------------------------------------------------------------
  456-  495 (59.51/42.65)	ERELFTRKFVEvnytDGSCDSRWSLTSFPWTKKLEVNNKK
  619-  654 (65.28/37.52)	NRELLARIVVD....EAHCVSQWGHDFRPDYQGLGILKQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.65|      37|     160|     793|     839|       4
---------------------------------------------------------------------------
  793-  839 (59.40/62.98)	VIHHSLPKSIEGYHQEC....GrAGRDglqsscvlyYSYSDYMRV.KHM.....LVQ
  945-  991 (50.25/31.29)	VYRGSLSQQVKRYKHELlslhG.AGKP.........LSKGDASRIlRHMvtedfLVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.13|      18|      21|    1030|    1048|       7
---------------------------------------------------------------------------
 1030- 1048 (27.54/18.63)	PQKANKPEKPEvTPAKGQL
 1054- 1071 (32.60/17.97)	PKIYDSPTQPQ.SEADPKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.66|      21|      25|    1169|    1193|      11
---------------------------------------------------------------------------
 1169- 1193 (26.23/27.70)	RETSVtpTTNPLpnDDFFEDVSLSK
 1195- 1215 (34.43/19.62)	RVTDV..DKNEI..RDKFSSVAAEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.55|      12|      25|     280|     291|      12
---------------------------------------------------------------------------
  280-  291 (23.02/ 9.63)	HYEATGTPQPSL
  307-  318 (26.53/12.12)	RYPNGCPPPPEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.25|      15|      23|     555|     570|      13
---------------------------------------------------------------------------
  555-  570 (21.99/17.63)	QDQIMHLLqANISAAY
  580-  594 (29.26/18.55)	QQQIFREL.ASGCCTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.86|      21|      23|     861|     883|      14
---------------------------------------------------------------------------
  861-  883 (34.07/27.16)	RILE.ANI.ENLLRMvsYCENDVD..C
  885-  909 (28.78/16.28)	RLLQlAHFgEKFDPM..NCRKTCDncC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.98|      17|      27|       5|      31|      15
---------------------------------------------------------------------------
    5-   22 (32.68/32.88)	PLSKG.WPRLGlWRAYAWR
   33-   50 (31.29/10.18)	PVPKGsFPEIN.WLHHANR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP33407 with Med34 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) EERQRSHSLASTSTAGVFNPQTPHNVKMSNSY
2) IDLDDSEMTDDHHGQGGRILPTWLNPKSKPG
3) NKPEKPEVTPAKGQLQLGKTPKIYDSPTQPQ
4) NVASEEMKTRAPNLTGTMMAGVSQQHQRNLSSHVVASM
5) SGNYENIESYKRRRETSVTPTTNPLPNDDF
6) VSDSLLGTEMSSTRTVMDKREFGHVDAEVTSTVTPGKPNMHVPP
392
1229
1034
162
1156
207
423
1259
1064
199
1185
250

Molecular Recognition Features

MoRF SequenceStartStop
1) GRILPTWLN
2) RLGLWRAYA
3) TSPLFEDYAFRSQT
1245
12
1262
1253
20
1275