<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33398

Description Uncharacterized protein
SequenceMELPFRDRGSLMVLALIASGCLFAFVVAKEEATKLGTVIGIDLGTTYSCVGVYKSGHVEIIANDQGNRITPSWVAFTDTERLIGEAAKNQAAVNAERTIFDVKRLIGRKFEDKEVQRDMKLVPYKIVNKDGKPYVQVKMKDGDTKVFSPEEISAMVLIKMKETAESFLGKDIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGMDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDNRALGKLRRECERAKRALSNQHQVRVEIESLFDGLDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLEKNEIEEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAFGAAVQGSILSGEGGEETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRELGKFELSGIPPAPRGVPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLTQAEIDEMIREAEKYAEEDKKVKEKIDARNALETYVYNMKNTIGDKDKLGEKIEASEKEQIEAALKEALEWMDENQSAEKEDYDEKLKEVEAVCNPVISSVYQRSGGAGGSGEEDEDSSHDEL
Length665
PositionUnknown
OrganismAmborella trichopoda
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Amborellales> Amborellaceae> Amborella.
Aromaticity0.06
Grand average of hydropathy-0.431
Instability index31.12
Isoelectric point4.99
Molecular weight73330.33
Publications
PubMed=24357323

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central
plant-type vacuole membrane	GO:0009705	IEA:EnsemblPlants

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein folding in endoplasmic reticulum	GO:0034975	IEA:EnsemblPlants
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33398
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.71|      16|      16|     184|     199|       1
---------------------------------------------------------------------------
  184-  199 (26.83/20.08)	NDAQRQATKDAGVIA.G
  201-  217 (21.88/14.94)	NVARIINEPTAAAIAyG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      70.30|      19|      21|     135|     154|       2
---------------------------------------------------------------------------
  115-  131 (21.85/11.18)	...VQRDMKLVPYKIVNKDG
  132-  151 (27.08/12.22)	KPyVQVKMKDGDTKVFSPEE
  153-  171 (21.37/12.72)	SAmVLIKMKET.AESFLGKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      26|     232|     242|       3
---------------------------------------------------------------------------
  232-  242 (20.46/13.13)	LGGGTFDVSIL
  260-  270 (21.85/14.56)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.59|      20|      32|     551|     570|       4
---------------------------------------------------------------------------
  551-  570 (32.45/18.37)	IREAEKYAEE.DKKVKEKIDA
  585-  605 (26.14/13.38)	IGDKDKLGEKiEASEKEQIEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.94|      12|      15|     313|     325|       5
---------------------------------------------------------------------------
  313-  325 (16.52/14.25)	RVEIESLFDGLdF
  331-  342 (21.43/12.87)	RARFEELNNDL.F
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.22|      11|     193|     221|     231|       7
---------------------------------------------------------------------------
  221-  231 (20.87/13.15)	KGGE..KNILVFD
  415-  427 (15.35/ 7.61)	EGGEetKDILLLD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33398 with Med37 domain of Kingdom Viridiplantae
Unable to open file!