<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33235

Description Uncharacterized protein
SequenceMDEAVQRRTELDRASIAPSQYKPPSRVTLNEAKLANYVKDLADPSVPLTRLSRSVPHGFRGEKLFEMLWAGGALPAAAASTASGYFNPRVAPLGTASTPSSATTPGASIPSSASAARKSVDISRAVWFIRALGVAELSSLRNKSAATIVPEITSNLCTWMAKQVTELTLVQAAESSSTAAASPAPFSPSSYLPRTPGAGPPTSLSRSVATAHIARTPSNLHPAASPSPAPGKEVCSVLQNEVDEERWLAKWSYSLSLARHLHAQNLLDRAILVRWIVDAFAASNLVQLPFLIELVQEVLTFILRRRCFVKPFLTALLIQISSLDARFDRTTSPALRTKLMLLFRIVCETSPDALVSPRLWSEHADTLTQLLAEVATDADGLPSEHATQTMSDFVEHVVKPRVDRLLLRPANRQGSKEDSSTATSSPATATLQQHLDMEALDSFDMRTIDRVFLQTSGGNHRHTKQERDDSVWAPRIETILSWACSDRRSGVARQYLAATLIEKIRFGVTWEESSEETDQVSLPAFDLEHHTKKTRKINVEPMLIKWLGDVEASLSPISDGVIGASHTSLLATIDVTAIVVLVGELARRGIFSYTKYLQRLIARGMTTASASSAGNDACAVAPPSSGSLSRDSLHLRLLRSLPLYDQPASVYQQRRQAIYGDRTKETYEDAVQRRALRQLQSFLPFAFVEQEEQQESADPPAASHPASVPEENGSGDLEQALSRLWSASRFVRCRIFRNELLPAVTTRIERINGNQLSMVSAVLVMADDFEGLAQLLATLLLRPLSDSLARATFNMVIEHSLVWRSMDIMGTLNQLVRQQLNHSSSVRNDRQAVMASTTLLRLRTLIEGIPGRISAPALDPGAETDAIHQHVQALRPSVDTLLDRFANISRVAAEATEAGKTPPEGSDILTPFRSLFLQSDATGDEVIERTIVESVLARSDHSLVPAAVRLIDQLYLEASLEIDERHARWLSHLAHSIEQGTHGGKSIGALLALLTRLIAHGTLNLQLAMDAFLLPSLLSSVRRLTDPATRGTETSSNIGAIARVVSEIFSSVTDEVTSTISYEDMRAFGAQTMLLFAHVNLPSLLGAASCLICASDAATSIDAADKASIETFWKALLRSQPMQIAFRQDPRLCILTIKDTCKSMWGCNPSRVIDLAMGCLDPTSLLLQDVASVDAASIKARLDGWDTAVVAKELVEIFERLQLVESSFQSRADSKTKALASGIFDDLFVRLPATGAQVMRDCQSSGLISRFTDIGIKILSDKVKASKAATEGSTLDSRDAAKDSYVETAAPDEPNPSSSAQTGSSTAPMKSSKPSQEDEGVDSTMRSVLRMCEQQDSFTFNATDADSCGQLLLHVVSFLEHALSPTDSRTTDVATQLLQLLHSGTFQLLHLVLRFGCLWSVPMKAVAQRLVKSLLDLTRQAGQLPDCSTPFTLLLDSLSFVLDELPAQLLSACLPELETQLAELELATHERTSKMQQLSFRLDNAAGQWLVASSAESAVRKGWFTAGGLNAWECAEYLDAPPTIAPAASGNAVRGVPLQTRPIYARPDPASQTDAAAVPGARTGWSTKLTLNTSIPLTLLGLRVTRDLVPNYSTDSPSATSVGSNAEPAPTQTGLDATLPVFVESERTYGGRVGGEPAFARDVRRGLLLRPTLPVVQDVSTAIGQDGIQKVVSGTGRGSEKTTVGLTNDAIPVIDLKWDDDEVMPLQQPPAVTAASQGSRKRRMSKRD
Length1728
PositionKinase
OrganismKalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Ustilaginaceae> Kalmanozyma.
Aromaticity0.05
Grand average of hydropathy-0.107
Instability index51.39
Isoelectric point5.90
Molecular weight187264.46
Publications
PubMed=24356824

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33235
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     156.45|      29|     292|    1296|    1325|       2
---------------------------------------------------------------------------
  175-  203 (31.35/10.18)	..SSSTAAASPAPFSPSSylPRTPGAGPPTS
  210-  233 (33.32/ 8.99)	TAHIARTPSNLHPAASPS..PAPGKE.....
 1296- 1324 (47.18/16.87)	PSSSAQTGSSTAPMKSSK..PSQEDEGVDST
 1590- 1618 (44.60/15.41)	PNYSTDSPSATSVGSNAE..PAPTQTGLDAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.52|      14|      52|     863|     884|       3
---------------------------------------------------------------------------
  395-  408 (25.42/ 7.93)	EHV..VKPRVDRLLLR
  869-  884 (21.10/11.08)	QHVqaLRPSVDTLLDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.32|      32|     292|     468|     510|       4
---------------------------------------------------------------------------
  468-  500 (52.14/48.93)	DDSV.........................WAPRIETILSwACSDRRSGVARQYLAATL
  517-  573 (41.18/15.78)	TDQVslpafdlehhtkktrkinvepmlikWLGDVEASLS.PISDGVIGASHTSLLATI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.70|      37|     292|     597|     650|       7
---------------------------------------------------------------------------
  597-  650 (53.70/45.42)	LQRliargmttasassagndACAVAPPSSGSLSRDSLHLRLLRSL....................PLYDQPASV
  652-  708 (52.01/21.91)	QQR.................RQAIYGDRTKETYEDAVQRRALRQLqsflpfafveqeeqqesadpPAASHPASV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     349.76|     102|     362|     986|    1091|       8
---------------------------------------------------------------------------
  266-  393 (68.51/32.58)	....LLdrAILVRWIvdAFAASNLvQL...PFLIelvqevltfilrrrcfvkpfltalliqiSSLDARFDRTTSPALR...................TklmllfrivCETSPDALVSPRLWSEHADTLTqllaevatdaDGLPSEHATQTMSD.F...........................
  986- 1091 (161.12/99.81)	SIGALL..ALLTRLI..AHGTLNL.QLAMDAFLL............................PSLLSSVRRLTDPATR...................G.........TETSSNIGAIARVVSEIFSSVT..........DEVTSTISYEDMRA.FgaqTMLL....FAHVNLPSLLGAAsCL
 1347- 1454 (120.13/64.82)	SCGQLL....................LHVVSFLE............................HALSPTDSRTTDVATQllqllhsgtfqllhlvlrfG.........CLWSVPMKAVAQ...RLVKSLL..........DLTRQAGQLPDCSTpF...TLLLdslsFVLDELPAQLLSA.CL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.97|      19|     378|    1169|    1187|       9
---------------------------------------------------------------------------
 1169- 1187 (34.24/21.12)	DVAS.VDAASIKARLDGWDT
 1548- 1567 (31.73/18.97)	DPASqTDAAAVPGARTGWST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.26|      20|     719|     241|     260|      10
---------------------------------------------------------------------------
  241-  260 (37.40/23.43)	EVDEE..RWLAKWSYSLSLARH
  961-  982 (32.86/19.66)	EIDERhaRWLSHLAHSIEQGTH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.19|      22|     378|     885|     906|      13
---------------------------------------------------------------------------
  885-  906 (37.18/29.62)	FANIS.RVAAEATEAGKTPPEGS
 1251- 1273 (31.01/23.09)	FTDIGiKILSDKVKASKAATEGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.83|      13|    1380|     109|     128|      21
---------------------------------------------------------------------------
  109-  128 (19.59/24.75)	IPSSA.SAARKSvdisravWF
 1491- 1504 (21.24/10.20)	VASSAeSAVRKG.......WF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33235 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DSRDAAKDSYVETAAPDEPNPSSSAQTGSSTAPMKSSKPSQEDEGVDSTMR
2) KWDDDEVMPLQQPPAVTAASQGSRKRRMSKRD
3) PNYSTDSPSATSVGSNAEPAPTQTGLDATLPV
1276
1697
1590
1326
1728
1621










Molecular Recognition Features






MoRF SequenceStartStop




1) GSRKRRMSK
1718
1726