<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33136

Description Uncharacterized protein
SequenceMQRYHAANCTSAVNNSAIGGPSARDSGRADSSSIGNYPLNSRRPPPLTPYKLKCEKDGLNSRLGPPDFHPPTSSSPEENLTKEYVQFGYKETVDGLKEAEEIILTQVHTFSKPVVLKCKDAVRKCLRAINESRALKRKAGQVYGVPLSGPLLCKPGFPEQRSCGEETKKKWIESLSQQHKRLRSLADNIPGYRRRTLFEVLVRNNVPLLRATWFVKVTYLNQGHLTRHKLLGVSNGQKMLLNICNTSWMNFCHEIVHILLSKLGIGRHRCSIQDQCKKLVQHHQVFTVKKHLCILNGGIWCVFYSGTMLKGFFFLISLLIGFSGSYRWDSFLRLCDFPFCFTAGKGESIVLSQTYVQSLVAIAVRFIQEPAPGGSDLVDNSRRAYTLSALIEMVRYLVLAAPDTFVASDCFPLPPSIAACGPNDVSYASKAYENLQKRRSNSAEISAQFQGRGVDSRFEFLSFDYTISTIQRSAEDLAKIASAGYPQHNVAKAVQALDKALSDGDIRAAYCYLFEDLCNGAVDETWIAEVSPCLRSSLRWIGAISTSFVCSVFFLIEWATCDFRDFRAGVPKDIKFSGRKDCSQVYLVIQLLKQKILGGEFAARRGKNRRSNFLGVSKPSGSMDAFESPGPLHDIIVCWIDQHEVHRGGAKRLQLLVFELIRFGMFNPIAYVRQLIVSGMIDVIQPAVDPERRMRHHRILKQLPGCFVHDILEEAQLLGGNNLPEAVRIYSNERRLLLRELLVGKGKYLNNLVLSDEKSKKNSTSHLSVDLPRTFNAMTDNEGLRKHTKSSVDIRELKERIAALLQFPGPSCGVTIPVRDELQSSVKGSSGSVYSKMDELEATPGCEDCRRAKRLKMNDEKSSCDQGSSPSASDEEDNWWIKKGLKTLEPSLKVDPPIELTKQIPRGRQKMARKTQSLAQLQAARIEGSQGASTSHVCNNRVSCPHHGPGVEGENHKVVDVIRTSTPVDIVSIGNSLKQLQFVDKRSIAVWLTTVVRQLVEESEKSSVRVGQINRGAPVEEKSTTRWKLGADELSSILFLMDISLDLVSVVKFLLWLLPKANSSPSFAVQGGRNLLIVPRNVENNVCEVGEAILVSSLRRYENILLSANLVPEAMTALMTRAASLMSSNGKISGSAALVYARYIFKRYGSLPSVVEWHNNFKTTCEKRLLSELDHSRSGNGEYGIPLGVPAGVDNPDDYLRKKISISGTRPSRVGLNMREVVQRHVEDATHYLRKIIGTGTMKAVLADKNDDGYQVAQQIVVGLMDCIRQTGGAAQEGDPSLVSSAVSAIINSVGISVARISDFSVGNVYQNHLSGVDSSNIARYILQIHITCLCLLKEALGERQSRVFEIALATESSTALAGAFAPGKGSRGQHQLSPESYDSNVNNTTNDIPNGTGKIAPSKATKVVAAVSALVIGAITHGVITLERIVGLLRLREYLDFVQFVRRTKASSNGSARSVGASKVENPIEVYVHWFRLLVGNCKTVSEGLVWELVGESSVVALWRMQRMLPLKLVFPPAYSIIAFVLWRPFVSNGNSNSSVHEDTPRLYQSLTMAFHDVIKHLPFRDVCLRDTQGLYELIVADSTDAEFASVLELNGLDMHLKSVAFAPLRARLFLNSIIDCKVPSSGYSHEGVSEAKNRHQGNGTKLVDKLVSVLDCLQPAKFHWQWVELRLLLNEQALTEKLENHDMPLTDAIRSSCPTSEKPDASENEKNFIQILLTRLLVRPDAVPLFSEVVHLFGRSVEDSMLKQAEWFLAGQDVLFGRKTIRQKLIIVGESKGLPTKPQFWKPWGWCSNASSDPITANKAGKKRKLEVTSIEEGEVTEEGLGLKKVLLPRTLDESSPSVGYGITTERAFVQLVLPCIDQSSDESRSTFVNELVRQFSNIEQQLSSVTNRSITNNKHMGTASSGSEVSSNKASTRKGLRGGSPSLARRSSTNTTDTASPPSPAALRASMSLRLQFLLRLLPVICGETSFRNTRHTLASTIVRLLGSRVVYEDSAVCSPRSDVSKAETESTVDPFSMADLSSEVLFDRLLFVLHGLLSNHQPNWLKPRSSSNESSKDFTAFDRDAAESLQNELARMQLPDTIRWRIQAAMPILLPSLRCSLSCQPHSVPPTALALVQPSGSAAAAGLNQRNSAAIPKTGTAAAQGKLKQTMLSPSQQQEPDNTDVVDPWTLLEDGTSSGPSSSNASNSSDMGNLRATCWLKGAVRVRRTDLTYIGSVDDDS
Length2225
PositionKinase
OrganismEutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Brassicales> Brassicaceae> Eutremeae> Eutrema.
Aromaticity0.07
Grand average of hydropathy-0.220
Instability index46.25
Isoelectric point9.01
Molecular weight245394.66
Publications
PubMed=23518688

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33136
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.83|      11|      19|      39|      49|       2
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   39-   49 (23.55/13.10)	LNSR.RPPPLTP
   59-   70 (20.27/10.07)	LNSRlGPPDFHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.52|      18|      19|     465|     482|       5
---------------------------------------------------------------------------
  465-  482 (27.53/16.80)	YTISTIQRSAEDLAKIAS
  485-  502 (28.98/18.06)	YPQHNVAKAVQALDKALS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.98|      14|      19|    1069|    1084|       7
---------------------------------------------------------------------------
 1069- 1084 (19.63/16.52)	VqgGRNLLIVP.RNVEN
 1089- 1103 (19.35/ 8.87)	V..GEAILVSSlRRYEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     167.89|      49|     239|     266|     316|       8
---------------------------------------------------------------------------
  266-  316 (88.07/74.11)	GRHR...CSI.QDQCKKLVQHHQVFTVKKhlCILNGGIWCVFYSGTMLKGFFFLI
  504-  556 (79.82/59.44)	GDIRaayCYLfEDLCNGAVDETWIAEVSP..CLRSSLRWIGAISTSFVCSVFFLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.49|      16|      22|    1490|    1505|       9
---------------------------------------------------------------------------
 1490- 1505 (29.98/21.60)	LVWELV..GESSVVA..LWR
 1510- 1529 (20.51/11.90)	LPLKLVfpPAYSIIAfvLWR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     350.19|     129|    1060|     925|    1063|      10
---------------------------------------------------------------------------
  925- 1042 (160.57/113.68)	.......................................RIEGSQGA.STSHVCNNRVSCPHHGPgvEGENHKVVDVIR..TSTPVDIVSIGNSLKQLQFvDK..........RSIAVWLTTvvRQLVEESEKSSVRVGQ......INRGAPVEEKSTTRWKLGAdELSSILFLMD
 1954- 2102 (159.39/95.32)	MSLRL......QFLLRLLPVICGetsfrntrhtlastivRLLGSRVVyEDSAVCSPRS.................DVSKaeTESTVDPFSMADLSSEVLF.DRllfvlhgllsNHQPNWLKP..RSSSNESSKDFTAFDRdaaeslQNELARMQLPDTIRWRIQA.AMPILLPSLR
 2103- 2171 (30.23/16.22)	CSLSCqphsvpPTALALVQPSGS....aaaaglnqrnsaAIPKTGTA.AAQGKLKQTMLSPSQQQ..EPDNTDVVD....................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.67|      12|      19|    1593|    1604|      11
---------------------------------------------------------------------------
 1593- 1604 (21.05/13.45)	LELNG.LDMHLKS
 1614- 1626 (17.62/ 9.90)	LFLNSiIDCKVPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.73|      40|     238|     609|     654|      12
---------------------------------------------------------------------------
  609-  654 (66.53/62.86)	RRSNFLGVSKPSGSMDAFESPGPLHDIIVCWIdqhevhRGGAKRLQ
  850-  889 (71.20/51.19)	RRAKRLKMNDEKSSCDQGSSPSASDEEDNWWI......KKGLKTLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.03|      25|     385|     717|     747|      14
---------------------------------------------------------------------------
  717-  747 (35.77/28.72)	LLGGNNLPEAVRIysnerrLLLR..ELLVGKGK
 1105- 1131 (38.26/18.59)	LLSANLVPEAMTA......LMTRaaSLMSSNGK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33136 with Med12 domain of Kingdom Viridiplantae
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