<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33062

Description Uncharacterized protein
SequenceMQFTPLQLKEKLLGALDEENNIVNTSVVLEVITILEKFPITREALEITRIGRYVNELRKKTSNEELAKRAKKLVRGWQKLVTVPEGPHINGDSISTPPQHRNISALQNAGNGSKPSSPAISSPAINRNCVVRSSLSPAIGNRPVTPSQQRTLQPNKLGKAGDLNKSKHSPGLSKTLPSALKPVVNSPKQTLNVQTSNLSPAVSQTFPPQAKAESSGKSVKSSPKSRPSTPCQSPSLTCSSQSAVTIGNEDSLSSLPCTPTSVDNLQTGNGHTKRKKRGRKPKSGKKSNHSAESAISPNDGCSRSEQCDVPKTDIANRKRVRLDKLSTTPVKQQKLNTSIHSLSSKQPLNGIVYSDKTCHNAVVNNSANSDPKTQSTSTEYSTPGSKKSLMRQDSTKPAVKTPKVKTTAELIADYQQKTGSTSYGNNILEKLRTNQIDHESDVQTSVLPPGIKPRKKRISNDSSILSVPSPSLSQTKTELVEKFLQTSVSPTLTDLSPPLEDYSLKSESPINSSQNSVQASTSDLKITIKSVPSVSIDQQKIAESKPLCAYNHSEISNVKHSTEISESTENKVEKRLTIEEIYSQLPPIDFDSINWECTDYIVPEPTPSNDLDVNRIINDQWEGINGSLDKDKVWHDWASTLTLSSVDDDPLHVLPYVDVND
Length661
PositionUnknown
OrganismLottia gigantea (Giant owl limpet)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Patellogastropoda> Lottioidea> Lottiidae> Lottia.
Aromaticity0.03
Grand average of hydropathy-0.710
Instability index56.14
Isoelectric point9.20
Molecular weight72040.97
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33062
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.85|      37|      40|     344|     380|       1
---------------------------------------------------------------------------
  344-  380 (63.05/36.16)	SKQPLNGIVYSDKTCHNAVVNNSAN..SDPKTQSTSTEY
  385-  423 (55.80/31.18)	SKKSLMRQDSTKPAVKTPKVKTTAEliADYQQKTGSTSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     233.46|      55|      61|     115|     172|       2
---------------------------------------------------------------------------
  115-  169 (98.37/34.40)	PSS..PAISSPAINRNCVVRSSLSPAIGNR......PVTPSQQRTLQP.......NKLG.KAGDLNKSKHS
  177-  226 (64.53/22.39)	PSAlkPVVNSPKQTLN.VQTSNLSPAVSQ........TFPPQAKAESS.......GKSV.KSSPKSR....
  227-  290 (70.56/22.42)	PST..PC.QSPSL..TCSSQSAVT..IGNEdslsslPCTPTSVDNLQTgnghtkrKKRGrKPKSGKKSNHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.19|      34|     248|     291|     324|       4
---------------------------------------------------------------------------
  291-  324 (58.49/27.06)	AESAISPNDGCSRSEQC.D..VP.KTDIANRKRVRLDK
  542-  574 (45.41/19.62)	AES..KPLCAYNHSEIS.N..VKhSTEISESTENKVEK
  581-  609 (31.29/11.58)	IYSQLPPIDFDSINWECtDyiVP.EPTPSN........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.70|      21|      41|     428|     448|       5
---------------------------------------------------------------------------
  428-  448 (34.76/18.29)	LEKLRTNQIDHESDVQTSVLP
  452-  469 (21.14/ 8.35)	..KPRKKRISNDSSI.LSVPS
  472-  490 (27.80/13.20)	LSQTKTELV..EKFLQTSVSP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33062 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EGPHINGDSISTPPQHRNISALQNAGNGSKPSSPAISSPAINR
2) NEDSLSSLPCTPTSVDNLQTGNGHTKRKKRGRKPKSGKKSNHSAESAISPNDGCSRSEQCDVPKTDIANRKRVRLDKLSTTPVKQQKLNTSIHSLSSKQPLNGIVYSDKTCHNAVVNNSANSDPKTQSTSTEYSTPGSKKSLMRQDSTKPAVKTPKVKTTAELIADYQQ
3) TSYGNNILEKLRTNQIDHESDVQTSVLPPGIKPRKKRISNDSSILSVPSPS
4) VRSSLSPAIGNRPVTPSQQRTLQPNKLGKAGDLNKSKHSPGLSKTLPSALKPVVNSPKQTLNVQTSNLSPAVSQTFPPQAKAESSGKSVKSSPKSRPSTPCQSPSLTCSSQSAVT
85
248
421
131
127
416
471
245










Molecular Recognition Features






MoRF SequenceStartStop




1) IKPRK
451
455