<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33044
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MTDNQGQGVSAFPSPPMQYINVYTDENIKRGRAPLPPPPISDNYMMFGAQFTADDAIIRPLEASNCRRLYPNNYDRKRELKKINHSILINFLDLLEVLIQSPESSKRQEKIEDMQILFINMHHLINEFRPHQARETLRVMMEIQKKKRLEIADCFQKHLDKVKELIEGSVNALPEDMDSKVLVTSELLQTKVVKAEPQSSYENCDRLDEMMTDIVDGMS |
Length | 219 |
Position | Middle |
Organism | Lottia gigantea (Giant owl limpet) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda>
Patellogastropoda> Lottioidea> Lottiidae> Lottia.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.555 |
Instability index | 56.73 |
Isoelectric point | 5.46 |
Molecular weight | 25352.86 |
Publications | PubMed=23254933
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP33044
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 143.46| 45| 69| 59| 103| 1
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59- 103 (76.22/55.73) RPLEASNCRRLYPNNYDRKR.ELKKINHSILINFLDLLEVLIQS.PE
129- 175 (67.24/48.37) RPHQARETLRVMMEIQKKKRlEIADCFQKHLDKVKELIEGSVNAlPE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 58.46| 15| 21| 3| 17| 2
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3- 17 (29.33/16.94) DNQGQGVSAFPSPPM
26- 40 (29.14/16.79) ENIKRGRAPLPPPPI
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