<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33039

Description Uncharacterized protein
SequenceMAAYPSQEHRPLKKQSLGPPDVYPQEHKQREDELNQSSVKHGFSNMPQFSDEHGSEKNADITIDKFGTYFSSVLTKKMEYNTLQDSKKRPTLPQKEIFWHGRSKPAVMEAWFKDLANDKPLSQMGKRVPLLNRKEDVFSTLCEYNISMVRASWFIKMMAVYNSATMENRNGKRRQTVDQASEWAIALTKYLKDQLQKIQEFYHGGSATQTSFLTAHTPLQSDMEIALKQWNYCCRLARHTYNEGLLDRHEYLSWLVELLEKMKQPDDTVLKLIIFQILHYMDEVTNSALLSRKLAYICSKKISLLCSDVGTTSPRTQSPMLTTNSNGICLCHGMWLIHGMCLIHGMCLCHGMCLIHGMCLSHGMCLIHSMCLIHSMCLIHSICLSHDMCLIRCMSLSHWCHKLLIETVWLFLQCRNQIRMCEQQIKQRGRMAEARWSSDKCQQSATGKGATISKVLTVLDLFDRHKFDLVDNANNMDSLYNKIFACTQNQDSNESVPTDDSVIRLLLDLAVSTRRCGDHRAIVVAKLLERRQSEIRSEKYGDNDMGDDKDSSGSDTMVTPSIPVFQHLLMDFLDTSAPVLEDNPSEENSLAFKNLIHLFCELTRHDVFSHDAYMCTLISRGELMRTPAPIVPFNDSLDLGSVKSLTESYSIKHEVDKGDINIPSVGESLQNSNQPKGPSRHMQYVTHFPLPLDEYSVHECNQRMMMLYGVGKARDEARHFQKKISKEVLRLYGKRNSIDINSGDLGKVRKKKEKEGEGAYTGQAPSLPNLEAIFQKFKKLSYFDQHAVTNQCVSTVLEQMISFIEGNSSYLAKVEHVAYLFDMMEHAMNINGLIDFIVKLLNQLCEVVTQLKIKESTLVSSYTMTLGLCIVSVLRNYNSYMLVSQEQTAEAFEGLIGVMRLLDVSNPADCTSPSRCMLAYLCDTYSCNIYLKNKYSEMFNAPYNKMKNTLYATVNASSSNLRWDPSFMIDVITGCKGQIDQQFVRQVQENSLNLYSFVCNATLNICGTQQPERLNDIAILCAEFTARCNALSSEWLGVLKALCCSSNNSCGFIDVLTQIDVSDMSIHDSLSVFTAILIARHCFSLQDFVIHVALPSLMSASGGDQDAESGARLTCHLLLRLFKTSHLTQPQPGLSSGSRNAPLIKSSADCHLLEAAHDSITVGGVLAVLKAILMLGDSYNDDDYKAKNTSSNTKDKSGDIFNLLQQLDDDEIDLNLLGSSMTSKNSGVERAGLSEFAKYSLREMCSQEWVREKFLKEPEYSLFHEDMLLDNLLSPKQAHQLLQMICYPTGVPNQYDGTETDNKSNIIRILQTLDKWSLRVSWLELQFMFKQSTSVAEKNSLLDIFAKGTIDLFHQQTESNKSTNTLSDYNNNFCSIFDLTRSDSDDSIWLVAPLISKLSANVQGRVLKSAGQVLESGNNLVSKSKFDKEKNQKSKSLLGHQPFLSLVLSCLKGQDEQREGLLNSLHSQLEKFIFNMKEILEKSPDEYKIRQDLHKDLQLRLSLVGGMIDTIQRNSTTTSEWALLLLMLISYGVVDTQTTNNELFTTVLDMLSVLIHGTLLSEEGDKGEENKKAYTNLIKKLKKELGDKQSNCIDRLRQLLPIPKRQYEVITCETYGTLVDTKGNKIAGFDSIGKKQGLQVAQKIKVNPWEVIEGYRNAHCIPWANFSAIKTEKKTLRYEEQHRLSLYHSHLLTQPDEYYLEAPPLPPEELEPPPEKVVSICVH
Length1723
PositionKinase
OrganismLottia gigantea (Giant owl limpet)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Patellogastropoda> Lottioidea> Lottiidae> Lottia.
Aromaticity0.07
Grand average of hydropathy-0.315
Instability index42.20
Isoelectric point6.31
Molecular weight195035.32
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33039
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.56|      45|      47|    1371|    1416|       1
---------------------------------------------------------------------------
 1371- 1416 (70.40/50.48)	NNFC..SIFDLTRSDSDDSIWLVAPLISKLSANVQGRVLKSAGqVLES
 1418- 1464 (70.16/45.54)	NNLVskSKFDKEKNQKSKSLLGHQPFLSLVLSCLKGQDEQREG.LLNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     149.46|      17|      17|     331|     347|       2
---------------------------------------------------------------------------
  327-  344 (39.68/21.45)	GIClCHGMWLIHGMCLIH
  345-  362 (41.06/22.45)	GMClCHGMCLIHGMCLSH
  363-  380 (36.66/19.26)	GMClIHSMCLIHSMCLIH
  381-  398 (32.06/15.93)	SIClSHDMCLIRCMSLSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.67|      38|      49|     571|     611|       3
---------------------------------------------------------------------------
  571-  611 (58.04/44.64)	DFLDTSAPVLEDNPSEENSlAFKNLIHLFCelTRHDVFSHD
  622-  659 (64.62/39.37)	ELMRTPAPIVPFNDSLDLG.SVKSLTESYS..IKHEVDKGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     459.42|     124|     714|     400|     540|       6
---------------------------------------------------------------------------
  400-  531 (197.09/151.40)	CHKLLiETVWLFLQCRNQIRMCEQQIKQR.GRMAEA..RWS...SDKCQ.QSATGKGATISKVLTVL.......DLFDRHKFDLV......DNANNMDSLYNKIFACTQNQDsnesvptDDSVIRLLLDLAVSTRRCGDHRAIV..VAKLLERR
 1115- 1243 (173.78/114.99)	CHLLL....RLF..KTSHLTQPQPGLSSG.SRNAPL..IKS...SADCHlLEAAHDSITVGGVLAVLkailmlgDSYNDDDYKAK......NTSSNTKDKSGDIFNLLQQLD.......DDEIDLNLLGSSMTSKNSGVERAGLseFAKYSLRE
 1278- 1370 (88.55/57.11)	AHQLL.QMICYPTGVPNQYDGTETDNKSNiIRILQTldKWSlrvSWLEL.QFMFKQSTSVAEKNSLL.......DIFAKGTIDLFhqqtesNKSTNTLSDYN....................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.94|      33|      51|    1017|    1051|       7
---------------------------------------------------------------------------
 1017- 1051 (56.23/37.36)	IAILCAEFTAR.CNALSSEWLGVlkALCCSSNNSCG
 1070- 1103 (51.71/28.76)	LSVFTAILIARhCFSLQDFVIHV..ALPSLMSASGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     234.22|      80|     681|       5|      98|       8
---------------------------------------------------------------------------
    5-   98 (116.44/117.58)	PSQEHRPLKKQSLgPPDVYP.QEHKQREDEL.....NQSSVKHgFSNmpQFSDE....HGSEKNADITIDKFGtyfsSVLTKKMEyntlqdSKKRPTLPQKE.IF
  678-  774 (117.77/78.27)	PSRHMQYVTHFPL.PLDEYSvHECNQRMMMLygvgkARDEARH.FQK..KISKEvlrlYGKRNSIDINSGDLG....KVRKKKEKegegayTGQAPSLPNLEaIF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33039 with Med12 domain of Kingdom Metazoa
Unable to open file!