<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33034

Description Uncharacterized protein
SequenceMDAETGVFPDINKPKQDEDKHQRMASLMDKLRARNPQHKVWTDSKLIKTPNMAEKRHVESTDKVLVQNCLDSIQRAIKVCNHQSLLERLESIARQVGLTFGTDNDLQVFISSDMFFIEIQLEKGGFIKDVKIVHQGDPVSCPELTEILQDGKFDEFITHLEGLQKIYQLTGDKKIKTKGYLALQSIEKDLNTLAQLQSSTINGVARYIHKTPLGILLPRKGGLPMELMYFVSPYDLLDKLSKTAHPLTLEAITEFNLGQRVTICMEPGPPKKLQTMPLMTINKTTDGKSLPSYTNISNINSHLLPACFTLVLKQPIPVSLSVVQKIQSITNIEIGEVGDVKPLLNLLIEKYSQGKIQPDQIRQLYVNLPDQHHTYFINGVNGGSLDQPGLMVSSVPFVHPTSVPRILNCLRQQLLFNTVVSSVIRPNSVKDAKSSVVCELTTISMQQLTVTFEHPAHDDIISIEIDLGDITNLKCKVVSTSEESLCSDDLASRIFTRCMSVPITVRTIFKKGKDLLQKATDEAKAAMRPPAIPPLVIKPRPPPPYLPPPQQLTPTMLPTNQQQMDMYPAPPPYSNIRSMSHEMVSPPNSVEKTTPLLANLLDHDGDTPTDSTDSPMLSRLLEEQPTGSVITLPPGPIPQPHQQQQHHQQQHHQQMPSQPQMSVAQQHMMVQQHQLSSQQQQMASQQHQMASQQQMASQQHQMASQQHQMASQQHQISSHSPSLQQQKRMRKRRSATDVFTGRSPKHRISDSSGGFDRLDTFDMDNSSSPFDAGGGGSIGGSAGLGGNFQASGSLGSVIDLTEDAFSGESSLKKLADSVDNIPREMSRQASIPDSELSALLAEGEVGGRPLISRSSPQNSKNEKASISLEGLLSEVGDNDEADDPILASRHLVPAPGPRSDNQIQADTYNSTLDVNLRNELFGTDLETSKSVQQLMTHRVPQSHDLLDSKYNAIYGKSSAKVNSDLSTDKKEITGIFEKLENLKGEQLKKEKTESVDRAESGGSMKLKLSTSGFRGGEGRLISSPAYSSEPVVTKKSGSCTFDFTSDESDEEPPSLGYSSSDRLSMTVYSQSPTRLSISNKAKNSDSLLKKTEKYKRKEAKYNLKGDSVKRKKLKDESKKERKKRKMTEGQAVYHSVESDQRTVTKLKIRVAKEPTVVLPDSPDKDKFGDSVKKQTVEKYVVSRQDSKESSKSQKSLHRSKSSLNSQGSSESGKADPKLAKATIRLKPLQIPNPGSSVTVNAGQKSGSASGKSFSEIKSVKSSSSNKTANSGNRTASPSITSASYKSPNSNFGKNTSPSVGNTGQTASSPILIGSGKNASPSISKSVISPNLSATSKISSPNLSGSGKINSPSLSASGKTSSPILSASSKSSSPSISGLAKSSSVNKTYNSANKSTSSSLSKSGSSSSNKTLSSSKSGSNLNSSRLNSSSSSKSSALSKSSSTSSLGSGSTSMSMSAYLPNAPSASKVARLPPIPKLSSSSKSASQASSISHSSALHSPPPQTSAYTSTSHSSSQSSNSTTDSSSNSSHKNKSNMQPMARARKGSLSAVIDKLTKATGTTNSVSDGSGQSDAPVSRDPRINNSKSDKILDRSVQNEKSNFSDKKVPRPDSINIDKFGNKQRSQENYVSKPVQKSPTTNKMNKSDYNKRALMNSDYSTHNKPRSVSDTVSSSPRLNSILTSSKSPTTKSSPVGILKNSQTNYNSEENRNVKISDSGNFKRERSHTPTILSQREDPRLIRNNSSTNLNSSADNSKTETEKQKVSVPSNIASPSEGALDLSLSDKIIPTSNVAPNQGLAFVSETTKFNGEVTKVEKASPKPPTLKSQIPQVRDNNIISEIPKNKAPTPSKGSFSPRSDASSPEIGLIIDCPASPDEDLTAIDTGPKGENWVKSDSMRTVQTPPSVKTLLKTTPSKDPTPPVLTASPISNSPCEIDDDLMDQALLGLGE
Length1944
PositionMiddle
OrganismLottia gigantea (Giant owl limpet)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Gastropoda> Patellogastropoda> Lottioidea> Lottiidae> Lottia.
Aromaticity0.04
Grand average of hydropathy-0.679
Instability index56.40
Isoelectric point9.34
Molecular weight210292.42
Publications
PubMed=23254933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33034
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     152.09|      19|      19|     674|     692|       1
---------------------------------------------------------------------------
  642-  652 (18.39/ 7.41)	....QQQQHHQQQH....H
  654-  672 (35.85/23.53)	QMPSQPQMSVAQQHMMVQQ
  674-  692 (39.04/26.48)	QLSSQQQQMASQQHQMASQ
  694-  712 (39.42/26.83)	QMASQQHQMASQQHQMASQ
  715-  729 (19.39/ 8.34)	QISSHSPSL.QQQKRM...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            12|     610.74|      62|      62|    1236|    1297|       2
---------------------------------------------------------------------------
 1027- 1106 (46.06/11.91)	S.SEP.VV..T.KKSGSctfdfTSDESDEEPPS..LGYSSS............DRLSMT.VYSQSPT......RLSISNKAK...N.SDsLL.................KK...........TekykrkeakynlkGD
 1180- 1227 (39.05/ 8.87)	..VVS.RQ..D.SKESS.....KSQKSLHRSKS....SLNS............QGSSESGK..ADP......................K.LA.................KA...........T..........irlKP
 1236- 1297 (100.88/35.65)	S.VTV.NA..G.QKSGS.....ASGKSFSEIKS..VKSSSS............NKTANSGNRTASPS......ITSASYKSP...N.SN.FG.................KN...........T.............SP
 1298- 1340 (41.17/ 9.79)	...SVgNT..G.Q...T.....AS....SPI........................LIGSG.KNASPS......I.SKSVISP...NlSA.TS.................KI...........S.............SP
 1345- 1379 (41.19/ 9.80)	S.GKI.NS.....PSLS.....ASGKTSSPILS..ASSKSS.......................SPS......I.............SG.LA..............................................
 1407- 1462 (48.44/12.94)	..........S.NKTLS.....SS.KSGSNLNSsrLNSSSS............SKSSALSKSSSTSS......LGSGSTSMS...M.SA.YL.................PN.........................AP
 1465- 1536 (55.48/15.99)	SkVAR.LP..P.IPKLS.....SSSKSASQASS..I.SHSSalhspppqtsayTSTSHSSSQS.SNS......TTDSSSNSS...H.KN..K.................SN...........M.............QP
 1546- 1622 (45.00/11.45)	S.AVI.DK..L.TKA.T.....GTTNSVSD.GS..GQSDAP............VSRDPRINNSKSDK......ILDRSVQNE...K.SN.FSdkkvprpdsinidkfgnKQ...........R.............SQ
 1623- 1683 (57.18/16.72)	E.NYV.SK..PvQKSPT.....TNKMNKSDYNK..RALMNS............DYSTHNKPRSVSDT......VSS....SP.rlN.SI.LT.................SS...........K.............SP
 1685- 1746 (37.13/ 8.04)	...TK.SSpvG.ILKNS.....QTNYNSEENRN..VKISDS............GNFKR..ERSHTPT......ILSQR.EDPrliR.NN.SS.................TN...........L.............NS
 1761- 1825 (50.27/13.73)	S.VPS.NI..A.SPSEG.....ALDLSLSD.KI..I..PTS............NVAPNQGLAFVSETtkfngeVTKVEKASP...K.PP.TL.................KS...........Q.............IP
 1832- 1899 (48.89/13.13)	I.ISE.IP..K.NKAPT.....PSKGSFSP.RS....DASS............PEIGLIIDCPASPD....edLT.AIDTGP...K.....G.................ENwvksdsmrtvqT.............PP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     145.09|      36|      38|     520|     557|       3
---------------------------------------------------------------------------
  520-  549 (50.67/20.79)	................TDEAKAAMRPPAIPPLV.IKPRP.......PPPYLPPP
  550-  588 (48.80/25.17)	QQLTPtmL.......pTNQQQMDMYP.APPPYSnIRSMS.......HEMVSPPN
  591-  640 (45.62/18.37)	EKTTP..LlanlldhdGDTPTDSTDSPMLSRL..LEEQPtgsvitlPPGPIPQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.53|      18|      18|     776|     793|       4
---------------------------------------------------------------------------
  776-  793 (33.16/17.26)	GSIGG.......SAGLGGNFQASGS
  843-  867 (23.36/ 9.72)	GEVGGrplisrsSPQNSKNEKASIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.65|      31|      64|     737|     771|       5
---------------------------------------------------------------------------
  737-  771 (51.57/41.90)	DVFTGRSPKHRISDSSGGFDRldtfDMDNSSSPFD
  803-  833 (53.08/32.70)	DAFSGESSLKKLADSVDNIPR....EMSRQASIPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.72|      12|      18|     969|     984|       6
---------------------------------------------------------------------------
  969-  980 (19.59/21.03)	KKEITGIFEKLE
  988-  999 (19.12/ 6.35)	KKEKTESVDRAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     194.37|      65|      95|     155|     227|       7
---------------------------------------------------------------------------
  155-  227 (95.44/88.36)	EFITHLEGLQK..IYQLTG.DKKIKTkgyLALQSIEK..DLNTLAQLQS.STINgvaRyiHKTPLGILLPRKGGLPMEL
  250-  320 (98.93/67.14)	EAITEFNLGQRvtICMEPGpPKKLQT...MPLMTINKttDGKSLPSYTNiSNIN...S..HLLPACFTLVLKQPIPVSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.94|      11|      19|     332|     342|       8
---------------------------------------------------------------------------
  332-  342 (19.04/10.91)	IEIGEVGDVKP
  348-  358 (19.90/11.75)	IEKYSQGKIQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.35|      10|      29|     392|     403|       9
---------------------------------------------------------------------------
  392-  403 (14.24/11.77)	VSSVpfVHPTSV
  420-  429 (18.11/ 7.14)	VSSV..IRPNSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.85|      11|     445|    1159|    1169|      13
---------------------------------------------------------------------------
 1159- 1169 (23.38/12.04)	PDSPDKDKFGD
 1607- 1617 (22.47/11.28)	PDSINIDKFGN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33034 with Med1 domain of Kingdom Metazoa
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