<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP33008

Description Uncharacterized protein
SequenceMAASYWDSTQRRFWEFSKEQLAALRQRKQDEERSLVQMYPLPEWRHLSLFFSQQLNRLAKRLQARQQALATAQVYLKRFYCKVEIRRTNPYLAMATALYLACKTEECPQHIRQVVQEAKVLWPDTHCLEIARLGECEFFMISELSSHLIIHAPYRTLQTLQAELGLTPDELTQAWSIVNDHYMTDLPLLYPPHVIAVTAIVWVLVLQPATSGGSNNGGGIGLMGQTMGTANGSGPGGNHTGVGGNNGAALGGMGGGGSSSIQPPPLLLSLSSLGPGTSTPGGGTPGTPGMSGMGTPTTAGGFPAMSSARSVAFAHAQAQVAAAAALLGGGGPMQHMPQGMNPGPAQSGYAGGNNNNNNNNNSNSVANAGSGNSNSTSEETPPADGGRTATMHWLIRWLAESGLDMEATIDCTQEMISFYMASEEYNEKLTREQINRFVKARGLDR
Length445
PositionKinase
OrganismSporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's disease fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Sporothrix.
Aromaticity0.07
Grand average of hydropathy-0.313
Instability index55.88
Isoelectric point6.42
Molecular weight47711.27
Publications
PubMed=24855299

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP33008
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     137.17|      16|      17|     270|     285|       1
---------------------------------------------------------------------------
  230-  246 (24.31/ 7.64)	ANGSGPGGNHTGvGGNN
  250-  265 (25.69/ 8.47)	LGGMGGGGSSSI.QPPP
  270-  285 (31.34/11.86)	LSSLGPGTSTPG.GGTP
  290-  303 (25.63/ 8.43)	MS..GMGTPTTA.GGFP
  327-  342 (30.20/11.18)	LGGGGPMQHMPQ.GMNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.77|      20|      26|      68|      87|       2
---------------------------------------------------------------------------
   68-   87 (35.04/19.55)	ALATAQVYL..KRFYCKVEIRR
   93-  113 (27.30/14.04)	AMATA.LYLacKTEECPQHIRQ
  114-  132 (29.44/15.56)	VVQEAKVLW..PDTHC.LEIAR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP33008 with CycC domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAALLGGGGPMQHMPQGMNPGPAQSGYAGGNNNNNNNNNSNSVANAGSGNSNSTSEETPPADGGRTATM
2) NNGGGIGLMGQTMGTANGSGPGGNHTGVGGNNGAALGGMGGGGSSSIQPPPLLLSLSSLGPGTSTPGGGTPGTPGMSGMGTPTTAGGFPAMSSARSV
323
215
391
311










Molecular Recognition Features






MoRF SequenceStartStop




NANANA