<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32963

Description ATP-dependent DNA helicase
SequenceMEDDILAELLNVEEELEEVQGQIRVLISRQDKLYEKQSELKALLEACQGSESPSNAKVSAPVENWAGSFEWDKEVDDIRFNVFGISEYRVNQCEIINAVMSGRDVLVIMAAGGGKSLCYQLPAILRNGVALVVSPLLSLIQDQVMGLSALGIPASMLTSNTSKEDEKMIYKALEKGEGELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYKNLSILKTQFPSVPMIALTATATQRVQTDLMEMLHISKCVKFVSTVNRPNLFYEVREKSSAAKVVIDEVTDFICGSYPNKESGIVYCFTRKECEQVAKELRERGILADHYHADMDANERERVHLRWSNNRIQVIVGTVAFGMGINKPDVRFVIHHSLSKSMETYYQESGRAGRDGLPADCLLFFRPGDVPRQSSMVFYENSGLQNLYDIVRFCQSKRSCRRNAFFHHFGEPLQDCNGMCDNCAHPTETKEVDASTQAKIIVSLLKEMQENDQRATMLQLVDKLKVNSRGSGGATPTIPDLKREELEQLIVQLVLDRVLKEEFQHTAYSTNAYVTIGPLWKQLVQGKKMVKLEISVNSRGSRTNIKAVKCKHLAGLELKLDDFRKELSSCHGGIFPHAVLSTQQISTLSTERPDSLEQLEKLIGKTKTEKYGERILDCIRQYVETEVPNGSVKEGDSIQHRPTKRAKTKKALINIDTSEDEQC
Length713
PositionUnknown
OrganismAmborella trichopoda
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Amborellales> Amborellaceae> Amborella.
Aromaticity0.06
Grand average of hydropathy-0.377
Instability index38.60
Isoelectric point6.45
Molecular weight80369.14
Publications
PubMed=24357323

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32963
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.81|      53|      69|     507|     566|       1
---------------------------------------------------------------------------
  507-  566 (75.94/72.92)	MLQLvdKLKVNSRGSggaTPTIPDLKREELEQLivQLVLDRVLKEE.......FQHTAYSTNAYVTI
  579-  638 (83.87/57.80)	MVKL..EISVNSRGS...RTNIKAVKCKHLAGL..ELKLDDFRKELsschggiFPHAVLSTQQISTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     194.97|      51|     195|     172|     238|       2
---------------------------------------------------------------------------
  172-  230 (79.67/82.44)	ALEKGEGELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLisidEAHCCSQwghdFRP.D
  370-  419 (81.46/58.17)	AFGMGINKPDVRFVIHHSLSKS..METYYQESGRAGRDGL....PADCLLF....FRPgD
  433-  460 (33.83/25.62)	....G...LQNLY.DIVRFCQSKRSCRRNAFFHHFG........................
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32963 with Med34 domain of Kingdom Viridiplantae
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