<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32944

Description Uncharacterized protein
SequenceMTTPRKMQEVLEELQGNPYYGKYADKIAKVQQVAPETFQSRVEGLAKKKIEPVKGRQFSQLLQPKEKLPEPLQANEPRLDELLKLELVQDKSADEIEAIWQQYHLAKDCTITAVIPSKDFEVMEQRAAQFPTFLFPLPRSQGYEFIMCQFEGNRVHLTPLLYFQVHKENAPECLTITHFKELQQKKGIVLMRGEYDGNVLNAKEAQCIANQLQMYYVQADERKLELLERFTRTPDRFDHMDLVEEISSLSLVPRTMSSLMMDYEFKMKTQTERVKVEDLFDYEGCKVGRGTYGHVYKGRRKDGSDSRDYALKQIEGTGLSMSACREIALLRELKHPNVINLVRVFLSHNDRKVWLMFDFAEHDLWHIIKFHRAAKANKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPHEKDWEDIKKMPEHPTLLKDFKKSNYLSCSLVKYMERHKIKPESKAFHLLQKLLLMDPNKRITSEQAMQDGYFSEDPLPTQDVFAGCPIPYPKREFLTDDDQEEKSDNKQRQNQQQQQQQQQQQQQQAPQQQQPQGQQQQSNQQDQHPAKRVRLTGPQGHPGQQMPISQQQQQDFHQQQMMFNNSQQQQQQNYQQRF
Length719
PositionKinase
OrganismDendroctonus ponderosae (Mountain pine beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Curculionidae> Scolytinae> Dendroctonus.
Aromaticity0.09
Grand average of hydropathy-0.734
Instability index52.73
Isoelectric point7.64
Molecular weight84107.21
Publications
PubMed=23537049

Function

Annotated function
GO - Cellular Component
mitochondrion	GO:0005739	IEA:UniProtKB-SubCell
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process
protein-containing complex assembly	GO:0065003	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP32944
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.43|      64|      68|     580|     647|       1
---------------------------------------------------------------------------
  580-  647 (108.02/55.90)	PNKRITSEQAMQDGYfsEDPLPTQDVFAGCPIPYPKREFLTDDDQEEksDNKQRQ...NQQQQQQQQQQQQ
  651-  717 (115.41/51.18)	PQQQQPQGQQQQSNQ..QDQHPAKRVRLTGPQGHPGQQMPISQQQQQ..DFHQQQmmfNNSQQQQQQNYQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.36|      25|      40|     362|     389|       2
---------------------------------------------------------------------------
  362-  389 (42.73/38.16)	HDLWhiiKFHRAAKANKKPVM..VP.KGMVK
  403-  430 (38.63/25.46)	HSNW...VLHRDLKPANILVMgeGPeRGRVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.78|      31|      36|      17|      47|       3
---------------------------------------------------------------------------
   17-   47 (51.62/32.25)	NPYYGKYADKIAKVQQVAPETFQS...RVEGLAK
   51-   84 (46.16/28.01)	EPVKGRQFSQLLQPKEKLPEPLQAnepRLDELLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.66|      34|      42|     120|     153|       4
---------------------------------------------------------------------------
  120-  153 (63.32/34.00)	FEVMEQRAAQFPTFL.F.PLPRSQGYEFIMCQFEGN
  163-  198 (51.34/26.38)	FQVHKENAPECLTIThFkELQQKKGIVLMRGEYDGN
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP32944 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) PNKRITSEQAMQDGYFSEDPLPTQDVFAGCPIPYPKREFLTDDDQEEKSDNKQRQNQQQQQQQQQQQQQQAPQQQQPQGQQQQSNQQDQHPAKRVRLTGPQGHPGQQMPISQQQQQDFHQQQMMFNNSQQQQQQNYQQRF
580
719

Molecular Recognition Features

MoRF SequenceStartStop
1) DQHPAKRVRLTGPQGH
2) PYYGKYADKI
667
18
682
27