<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32943

Description Uncharacterized protein
SequenceMIVVASLSVKADVIFLIEATAVNGAYIADLKTNYIIPSLEYFNQGSIDDNTLFAEISYCFYGIVTYQAADCLPSLTTDSFGPFSTPAKVLSAIEKLELIGGKGESHANIAEGLATALCCFEELQTKRDPNTVIQKHCILICNSPPYSIPVFECQAYSSKSAEELATILMEKNINLSIISPRKTFPLYKLFEKAGGDLSSSQTKNYAKDPRHLVLLKGYSLKERPVSPPTGNVQNNASQLVPGALPVTSMPSPLPGNDSPIHNTQLGTPQNPNMMGNNSPTVGQSPVYRSPNHPPQGRIMQGNQIGSIGMQGMPAPPGYPTGKYSPWFYLNLHALITENNYTGARPGWQMPPPGHQQPRPYMQVNAPNQQANPSTGGSALLAQLNQPPSMPTGNVNVNQFGQINVNTKILNQPNIQTSKAQNSTMQTSMPQSSQNSQIHPSQAQGSQPPTQQITNRDRPTIWQGLLEWNEKPKNANVENQKISKQVPCQVTCNTKDGEPELKADAWPPKLIMQIMPKQLIGNIGGSYLKNSTSVLFHPTQCEALDSLTRIMNSGFAGCVHFTSNPNPAACDIKVLILLYTADKKAYLGFIPNDQGAFVERLRAVIQQQKSNNIRIGASGPPMNPQAGGQMPMAAGQQIGGNNSNTSQSAQQQGLMMSQTNTHSMGGGQITQNLATQGQGPNLGQPGSGLGQPGPSLGQAGQSGQSASAIGSSGSGMGQIGGQPGQAPIGGMMGQSVGQPGPNQQQNMQQGMIGQPVQRGPFENQLQVERQQNLEKINKLKQTLEAAQQQEQQYKTQLERISHMKTTHLQEALQQAQHAEMQYKIMEQRMAAQGNPQVPQPNNPQQQRMIRPVMNNNPGLRHLLQQVSSKENVAPR
Length874
PositionUnknown
OrganismDendroctonus ponderosae (Mountain pine beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Curculionidae> Scolytinae> Dendroctonus.
Aromaticity0.05
Grand average of hydropathy-0.548
Instability index48.38
Isoelectric point8.91
Molecular weight94470.82
Publications
PubMed=23537049

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32943
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     183.47|      29|      30|     681|     709|       1
---------------------------------------------------------------------------
  251-  285 (32.62/ 8.29)	SPLPGndspihntQLG.TPQNPNM.......MGNNSPTVGQsP
  289-  313 (42.99/13.51)	SPNHP........PQGRIMQ.GNQI.......GSIGM.QGM.P
  618-  636 (36.41/10.20)	GPPM................N.PQAG......GQMPMAAGQ.Q
  678-  691 (30.03/ 6.99)	GPN............................LGQPGSGLGQ.P
  692-  722 (41.42/12.72)	GPSLG........QAGQSGQSASAIGssgsgMGQIG...GQ.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.99|      26|      27|     767|     793|       2
---------------------------------------------------------------------------
  741-  761 (35.66/20.54)	NQQQNM......QQGMIGQPVQRGPFE
  767-  793 (38.68/27.98)	ERQQNLeKINKLKQTLEAAQQQEQQYK
  797-  822 (43.65/27.12)	ERISHM.KTTHLQEALQQAQHAEMQYK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.87|      17|      24|     410|     426|       3
---------------------------------------------------------------------------
  407-  423 (24.33/ 7.94)	KILNQP.NIQ..TSKAQNST
  424-  441 (23.06/ 7.12)	MQTSMPqSSQ..NSQIHPSQ
  442-  460 (21.48/ 6.10)	AQGSQP.PTQqiTNRDRPTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.73|      24|      28|     186|     213|       4
---------------------------------------------------------------------------
  180-  208 (30.73/26.21)	PRKTFpL..YKLFEKAggdlSSSQTKNYAKD
  209-  235 (35.00/19.13)	PRHLVlLkgYSLKERP....VSPPTGNVQNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.28|      23|      27|     470|     496|       5
---------------------------------------------------------------------------
  470-  492 (40.55/32.01)	KPKNANVENQKISKQV.PCQVTCN
  498-  521 (36.73/17.87)	PELKADAWPPKLIMQImPKQLIGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.24|      32|      35|     321|     352|       6
---------------------------------------------------------------------------
  321-  352 (65.84/29.79)	GKYSPWFYLNLHALITENNY.TGAR...PGWQMPP..P
  353-  390 (47.40/19.41)	GHQQPRPYMQVNAPNQQANPsTGGSallAQLNQPPsmP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.81|      15|      24|     637|     651|       7
---------------------------------------------------------------------------
  637-  651 (25.51/11.79)	IGGNNSNTSQSAQQQ
  663-  677 (26.30/12.39)	MGGGQITQNLATQGQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32943 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KSNNIRIGASGPPMNPQAGGQMPMAAGQQIGGNNSNTSQSAQQQGLMMSQTNTHSMGGGQITQNLATQGQGPNLGQPGSGLGQPGPSLGQAGQSGQSASAIGSSGSGMGQIGGQPGQAPIGGMMGQSVGQPGPNQQQNMQQGMIGQPVQRGPFENQLQVERQQNLEKINKLKQTLEAAQQQEQQYKTQLERISHMKTTHLQEALQQAQHAEMQYKIMEQRMAAQGNPQVPQPNNPQQQRMIRPVMNNNPGLRHLLQQVSSKENVAPR
2) NYTGARPGWQMPPPGHQQPRPYMQVNAPNQQANPSTGGSALLAQLNQPPSMPTGNVNVNQFGQINVNTKILNQPNIQTSKAQNSTMQTSMPQSSQNSQIHPSQAQGSQPPTQQITNRDRPTIWQGLLEWNE
3) RPVSPPTGNVQNNASQLVPGALPVTSMPSPLPGNDSPIHNTQLGTPQNPNMMGNNSPTVGQSPVYRSPNHPPQGRIMQGNQIGSIGMQGMPAPP
608
339
223
874
469
316










Molecular Recognition Features






MoRF SequenceStartStop




1) NPGLRHLLQQVSS
2) QQRMIRPVM
855
844
867
852