<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32940

Description Uncharacterized protein
SequenceMAETLSGILNGIMKVDAMEEAFSCFLVHRSETERENIAKWQQELCDFFEGLNPEHLDFVLRQYLNVTSQSSRRRMQVLIELLEHCIRKGALQARKASEFIITTDQLHWSNAALWMNCFQLISDIIELVDYKGVRELMKGCCEKAKTLPLKLTSGVQPQCQILLKLVSKILDRDVCLLPGYLLTNELQKIYSECPHWTVASMFTDYVESFRPCAQMVSIIGHSQMRPVIEQSGCPDYVANPWKLDPITLRFALKGTLPYDPELTDKQVGLLRYAIQTPYSRDMISSMMNFNKQIVKPCQAIEDQLVELIIDALDRTEIDGDGTEGLWQHITSQLIYFVLFNFATFHNVVTTLVSRVQGKEVRRGRDQLMWVLLQFLSGSIQRNPVTNFFSVLKLYEALFPEHELPSPVQSEGADISLPLPNKLKAHLEFIQHLTTPSSNSFVTGTDYRVALLCNAYSTYQEFFNKPMMSLVESIQGGPKAGTPNCPLPTCPLSMTVLDSLTVHSKMSLIHSTVTQVIKLASSKSGIPLAPALVETYSRLLVYTEIESLGIKAFIAQLLPQVYKYHAWGILYTLLEMFSYRLHHIHPRYRVQLLTNLHSLAAVPQSNQTQLHLCVESTALRVITGKFSLSAPLSDFAKSRCLQDPKSIVSQESEELNRLLVLTLARAIHVTGSDGAWCHDLLVTIAQSTPHSWAPHSIECFPRPLQKFFAQHSVPQDNKQQLKKAVEEENRKWASMNNENDIMAHFGVPGAPPLFLCLVWKMLMETNHISPIVYKILERIGSRALSAHLRKLCDCLVYEFASSAGGQVVTKCIETINDMMFKYNIITIDRLVLCLALRTMEGNEAQVPSNQSLAKLKVLKSGEFRSRVTDFVRDNSPDYWNHTNWYEKHMEFLRKYPEKFAPEEQSSVINPYFSNVCLRFLPVLDIVVHRYLELYPVQKSLENLLDHVGCLFKFHDRPVTYMYNTFHCYETKLRDRPNLKRRLVSSLLSSLLTSFTEPYQQYLKTNSDDLWVPELDYYMQLTRRVVDRLNNPNSIYTTDWRFNEFPNAGAHILYITCVELMGLAAGPTSVGNGLLDKKNPPALFFAGYVIIPSKDIHSWINAIGLIMSALPISYWSVIHDRLLATLGELDSWRYDISPFRIFNFKETHLGLLENRFSYMLGLAHSIWHHAGPGQIATVPAWVAECLPSVVRTEEQFLFVCHLVGPFLQRITAVMQLTTSLYELLAQVDANQSELKHIDPICDFLYHIKYMFVGDSLRKEIEVIVRKLRSPLQYRLRAMGCKCKLTAVLILIGAAYVYIKLKRAPLEVPVIEEKWWATGPPREEDPTVRPFKINVPKEVIADLKRRLDTALPLQPPLEGVNQNYGINGELLGNIVDHWKTKYDWNKQQEFLNQFPQFQTKIQGLNIHFIHAKPKTVPQGVEVLPLLLIHGWPGSVREFYEIIPILTTPQKGRNFVFEVIAPSLPGYGFSDAAVRPGLNQAQIAQLFNKLMKRLKFDRFYAQGGDWGSAVSHDMAILYPENVIALHRNFCFAYEITNWKAYVGMYFPSLFFSEKEAAKIYPLSDAFNFIMLESGYLHIQATKPDTVGVALRESPVGLAAYIIEKFITWTDPQWKDLPDGGLTQKYTYDKLLDNVMIYWVTRSITTSARLYAEANSKSYRSLPLDKLPINVPAGCIRFSNELLYSSEVLLREQHPNLIHLSDAEGGHFAALEVPEVLAQDIIEFVGKVRTLPPKTNSKEL
Length1735
PositionTail
OrganismDendroctonus ponderosae (Mountain pine beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Curculionidae> Scolytinae> Dendroctonus.
Aromaticity0.10
Grand average of hydropathy-0.077
Instability index43.46
Isoelectric point7.09
Molecular weight197954.89
Publications
PubMed=23537049

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
hydrolase activity	GO:0016787	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32940
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.57|      39|      65|     417|     456|       1
---------------------------------------------------------------------------
  417-  456 (63.63/50.41)	PLPNKlKAHLEFIQHLTTPSSNSFVTGTDYRVALLCNAYS
  485-  523 (64.93/46.32)	PLPTC.PLSMTVLDSLTVHSKMSLIHSTVTQVIKLASSKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.26|      37|     461|     763|     800|       2
---------------------------------------------------------------------------
  763-  800 (59.32/51.15)	ETNHISPIVyKILERIGSRALSAHLRKLCDCLVYEFAS
 1231- 1267 (64.94/49.92)	ELKHIDPIC.DFLYHIKYMFVGDSLRKEIEVIVRKLRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     217.83|      72|     461|     527|     604|       3
---------------------------------------------------------------------------
  527-  603 (111.54/96.87)	LAPALVETYSRLLVYTEIESLGiKAFIAQLLPQVY...KYHAW..GILYTLLEM..FSYRLHHIH..PRyRVQLLTNLHSlaaVPQ
  634-  714 (106.28/70.44)	FAKSRCLQDPKSIVSQESEELN.RLLVLTLARAIHvtgSDGAWchDLLVTIAQStpHSWAPHSIEcfPR.PLQKFFAQHS...VPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     301.19|      96|    1282|     177|     354|       4
---------------------------------------------------------------------------
  184-  291 (149.46/204.91)	NELQKIYSECPHW..TVASMFTDYVESfRP..CAQMVSIIghsqmrPVIEQSGCPDYVANPWKLDPItLRFALKG.TLPYD...PELTDkqVGLLRYAIQTPYSRDMISSMmnFNK
 1382- 1485 (151.73/66.92)	NKQQEFLNQFPQFqtKIQGLNIHFIHA.KPktVPQGVEVL......PLLLIHGWPGSVREFYEIIPI.LTTPQKGrNFVFEviaPSLPG..YGFSDAAVRPGLNQAQIAQL..FNK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32940 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA