<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32934

Description Similar to High-affinity methionine permease acc. no. P50276
SequenceMEGAFMDLRREETQKTTGEPEVTEGVTVADRNVFNQTSDARRQLGVFSAIFLIFNRMVGTGIFATPSTILAMSGSVGLSLFLWVAGTFISATGMAVYLEFGTAIPRNGGEKNYLEYVYKSPKFLVSAMFASYVFLLGWAGSNSVVFGEYILHAAGVEVDRWNQRGIGVACLTAAFLIHGTALNWGIRVQNFLGSIKLLIILLIIVSGWACLGGAVKLPEKPHNFENAFEGTTGSAYGVVNALYNVMWSFVGYSNANYALSETKNPVRTLKIAAPTALILVGILYMLVNIAYFSAVPKDEILTSGRILAASFFRNVFGHAAEKALSVFVALSAFGNVLSVIFSQGRIVQELGREGILPASAFFASNWPFNAPLAGLFEHWIVSVIIVLAPPPGDAYNFILNVITYPLSVVNFFVSAGLIYIYFNRSKFPDYNPAIKATLPVVVIFTLANVYLVVAPFVPPEQGQSVYKTLPYWLHCVVGIAFLVAGAFYWVVWAVLLPKMGGYTLIRQTVIQEDGWSRNVFSREYIKSTSILLDHYTIIIMDNPQKSLESTRIRLQQLVQTIDSFRASLARRPPHELPPWDQLQNHFNVLSSSLDSLSSNLHTHFPAHGTTGLDAYPLANYPVRTQTVLLDTLLSKKPPAETFDAVWEALKAPPLGQGIEELWGKAAEIVRGIQEERSWEDEVVTMEEREEGTVREEDWVLGGEEGEGMEERRRRLEREMNALTGVLRFCATGVPIMEQPPLPKKR
Length745
PositionHead
OrganismPyronema omphalodes (strain CBS 100304) (Pyronema confluens)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Pezizomycetes> Pezizales> Pyronemataceae> Pyronema.
Aromaticity0.12
Grand average of hydropathy0.216
Instability index40.16
Isoelectric point6.03
Molecular weight82472.13
Publications
PubMed=24068976

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
transmembrane transporter activity	GO:0022857	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32934
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.75|      15|      15|      45|      59|       2
---------------------------------------------------------------------------
   29-   48 (17.92/ 8.59)	ADRNVFNQTSDarrqlGVFS
   49-   64 (20.83/11.13)	AIFLIFNRMVG....tGIFA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.58|      15|      16|     370|     384|       3
---------------------------------------------------------------------------
  370-  384 (27.84/14.92)	APLAGLFEHWIVSVI
  388-  402 (28.74/15.62)	APPPGDAYNFILNVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.31|      16|      68|     568|     583|       4
---------------------------------------------------------------------------
  568-  583 (32.66/19.99)	LARRPPHEL..PPWDQLQ
  633-  650 (23.65/12.51)	LSKKPPAETfdAVWEALK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.20|      14|      15|      93|     106|       6
---------------------------------------------------------------------------
   93-  106 (25.45/17.88)	GMAVYLEFGTAIPR
  109-  122 (25.75/18.19)	GEKNYLEYVYKSPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.63|      15|      19|     222|     236|       7
---------------------------------------------------------------------------
  222-  236 (27.22/14.99)	HNFENAFEGTTGSAY
  243-  257 (29.41/16.73)	YNVMWSFVGYSNANY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     173.69|      52|     202|     276|     327|      10
---------------------------------------------------------------------------
  276-  327 (85.67/49.74)	ALILVGILYMLVNIAYFSAVPKDEILTSGRILAASFFRNVFGHAAEKALSVF
  480-  531 (88.02/51.29)	AFLVAGAFYWVVWAVLLPKMGGYTLIRQTVIQEDGWSRNVFSREYIKSTSIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32934 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EDEVVTMEEREEGTVREEDWVLGGEEGEGMEERRRRL
679
715










Molecular Recognition Features






MoRF SequenceStartStop




NANANA