<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32928

Description Similar to Mediator of RNA polymerase II transcription subunit 31 acc. no. Q9USH1
SequenceMAAAQQPPTIPVAAPGRTRLEIELEFVQCLANPFYLCHLAQTKVLEDERFMNYVTYLNYWREPVYARMLSYPIYTLNALTLLAEPRFRIDIANAGVAYEMLSQMVQTFLPIPGGPTSLDLPGPTGADLPNPIDPNNPSTAADAAVAAAALGGALGNAPSAASGAVSAGASTTASATISARASANASATASGTASARASAPASKPSSSAPVPSSSRKAKLGELLIGIEDEPSGPSGPSPGLPGLPVKEEEDPEAVKAEMEQRKAKEEEDPGVVKAEMERKKAAKGLRWRENKKKRKEEEKKQKKKERNKKWKERQKRAREERRMAKEKKEVHSMEDQVAYHEDEIDDVYEEYEKLKAKEAGETADHKGKGKAIDRGGDEIQEQEEKEEEWSNPSTAAAVLAGGSGLGGNASATTSARALANAASKSSSSTPGPASKKAKINEANGSS
Length446
PositionMiddle
OrganismPyronema omphalodes (strain CBS 100304) (Pyronema confluens)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Pezizomycetes> Pezizales> Pyronemataceae> Pyronema.
Aromaticity0.04
Grand average of hydropathy-0.695
Instability index48.89
Isoelectric point6.27
Molecular weight47481.59
Publications
PubMed=24068976

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32928
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     115.08|      18|      19|     246|     263|       1
---------------------------------------------------------------------------
  229-  246 (21.83/10.41)	EPSGPSGPSPG...LPGLPV.........K
  247-  264 (30.64/17.87)	EEEDPEAVKAE...MEQRKA.........K
  265-  291 (21.38/10.03)	EEEDPGVVKAE...MERKKAakglrwrenK
  319-  339 (18.15/ 7.29)	EERRMAKEKKEvhsMEDQVA.........Y
  340-  357 (23.06/11.45)	HEDEIDDVYEE...YEKLKA.........K
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      83.14|      14|      14|     173|     186|       2
---------------------------------------------------------------------------
  156-  169 (21.22/ 8.34)	N..APSAASGAVSAGA
  170-  185 (18.99/ 6.67)	SttASATISARASANA
  186-  201 (20.42/ 7.74)	SatASGTASARASAPA
  408-  421 (22.51/ 9.30)	N..ASATTSARALANA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.16|      15|      20|      49|      63|       3
---------------------------------------------------------------------------
   49-   63 (32.11/25.42)	RFMNYVTY....LNYWREP
   67-   85 (22.05/15.30)	RMLSYPIYtlnaLTLLAEP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32928 with Med31 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASGAVSAGASTTASATISARASANASATASGTASARASAPASKPSSSAPVPSSSRKAKLGELLIGIEDEPSGPSGPSPGLPGLPVKEEEDPEAVKAEMEQRKAKEEEDPGVVKAEMERKKAAKGLRWRENKKKRKEEEKKQKKKERNKKWKERQKRAREERRMAKEKKEVHSMEDQVAYHEDEIDDVYEEYEKLKAKEAGETADHKGKGKAIDRGGDEIQEQEEKEEEWSNPSTAAAVLAGGSGLGGNASATTSARALANAASKSSSSTPGPASKKAKINEANGSS
161
446










Molecular Recognition Features






MoRF SequenceStartStop




1) ATTSARALANAASKSSSSTPGPASKKAKINEAN
2) KGLRWREN
411
283
443
290