<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32901

Description Mediator complex subunit 28
SequencePPPPPPPPPPPPPPPPPPPPPPPPPPPPGPPPPGPPGPPGLIPPPAGPRNPNNTLVDELEASFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVIKEDVSELRNELQRKEALIQKHLSKLRHWQQVLEDISVQHKKPAEMPQGPLAYLEQASANIPAPMKQT
Length189
PositionHead
OrganismFicedula albicollis (Collared flycatcher) (Muscicapa albicollis)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Muscicapidae> Ficedula.
Aromaticity0.04
Grand average of hydropathy-0.775
Instability index79.59
Isoelectric point5.42
Molecular weight20699.48
Publications









Function






Annotated function


GO - Cellular Component
cortical actin cytoskeleton	GO:0030864	IEA:Ensembl
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
GO - Biological Process
negative regulation of smooth muscle cell differentiation	GO:0051151	IEA:Ensembl
stem cell population maintenance	GO:0019827	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32901
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.75|      15|      15|       1|      15|       1
---------------------------------------------------------------------------
    1-   15 (44.81/ 7.75)	PPPPPPPPPPPPPPP
   17-   31 (44.94/ 7.80)	PPPPPPPPPPPPGPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.48|      15|      17|     116|     130|       2
---------------------------------------------------------------------------
  116-  130 (26.13/17.22)	QKPEQVIKEDVSELR
  134-  148 (23.35/14.74)	QRKEALIQKHLSKLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.14|      14|      18|     154|     169|       3
---------------------------------------------------------------------------
  154-  169 (21.65/17.42)	LEDISvqHKKPAEMPQ
  175-  188 (25.49/13.86)	LEQAS..ANIPAPMKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.80|      15|      22|      52|      73|       4
---------------------------------------------------------------------------
   52-   66 (25.01/31.35)	NNTLVDELEASFEAC
   77-   91 (26.79/14.11)	NGTDQEEIRTGVDQC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32901 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PPPPPPPPPPPPPPPPPPPPPPPPPPPPGPPPPGPPGPPGLIPPPAGPRNPNNTLVDELE
1
60










Molecular Recognition Features






MoRF SequenceStartStop




1) PPPPPPPPPPPPPPPPPPPPPPPPPPPPGPPPP
1
33