<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32869

Description Uncharacterized protein
SequenceQDELTAVNVKQGFSNQPAFSGDEHGSARNIVINASKIGAYFSSILAEKLKLNTFQDTGKKKPQINAKDNYWLVTARSQSAIHNWFTDLAGSKPLTILAKKVPILSKKEDVFAYLAKYSVPLLRAAWLIKMTCAYYAAISEAKIKKRQATDPNIEWTQIITRYLREQLAKVAEFYHVTTSQGNGSVVMPQEMEQALKQWEYNEKLSFYMFQEGMLERHEYLTWILDVLEKIRPTDDDLLKLLLPLMLQYSEEFVQSAYLSRRLAYFCARRLSLLLSDGPTLVAAHSPHMIIGPSNPPLAAPSPTAPGPAVSPVQLACSDFLSCPQHRPLVYGLSCMLQTVTLCCPSALVWNYSTNENKNINPGSPLDLLQVAPSSLPMPGGNSSFNQQVRAKIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRSDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESLSSASLTGSSLPVFQNVLLRFLDTQAPSLSDPNSDHEKTEFVNLVLLFSEFTRHDVFSHDAYMCTLISRGDLSITATARSRSPNGETVDEHYSKDHDMKMERKLKDHSIMEHMGIDSGTTSIFDDVDKSDFKIFSPMPGESCENMNSSLDRRISVTSEKSVKRERLRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRMILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGAQSAPAVPRHRDRRRLLCGDEGQKARKNKQEAFPTLETVFTKLQQLSYFDQHQVTSQISSNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHACLILNSEQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYSNVQPSNSNLLWDPEFMLDFIENPSAHSINYSMLGKILSDNAANRYSFVCNALMNVCMGHQDAGRINDIANLCAELTACCTVLSSEWLGVVKALCCSSNHVWGFNDLLCSVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDPDAEPGARMTCRLLLHLFRTPQVCLFPQETGKLFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAILMLGDAEIGSSSVNPLKSEDFTMRGLLEDLNEDEMWGSSHTLKSCGKAVSIETASLSEYARYVLRTICQQEWVGEHCLKEPERLCTDKDLILDPVLSNKQAQKLLQLICYPHGIKECTEGDNPQRQHIKRILQNLDQWTLRQSWLELQLMIKQCMKESGSGSVAEMNSLLDNIAKATIEVFQQSADLNNNSSNSGIGLFNPNSVGNADTISSSSERRGVWLVAPLIAKLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDVKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMQTNNELFTTVLDMLGVLINGTLASDLSNASQGGPEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDIITCEPMGSLIDTKGNKIAGFDSIDKKQKQGLQVSTKQKVSPWDLFEGHKNPAPLSWAWFGTVRVDRKVIKYEEQQHLLLYHTHPKPKPRSYYLEPLPLPPEEEEEEPTTPVSQEPERKSGELSDQGKHGMDDEKKTKGRKRKSKSSSRTDEYPQNNLYRVPPNYSPISSQMMHHPQSALWGYNIMGQPQQPGFFVQNQPLPPGGSRLDPTSSFVPTNTKQALSNMLQRRSGTMMQPPSIHAITPQQQLLQMKLLRQQAQNMVHIQYCYEGMPSLTVALKFSWGYTMYSTQMPLQQQQPGGVVLSPSYNPRAYTAAHSGPALMERLRQMQQQPSGYIQQQAAAYIQPLAGTQRLSHQPLQPNSLIGGGLDSASTTGPHPNLNSAQLPQEQMRQRQQQIRQQRLFQVRDPTAPKRPLGIRVKISTSVFQLQQGQQQGQQQPQTLGLQPVQPQQPLNLVQNQVLKCKDLVVPQQQDKQFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVNQYGHP
Length2157
PositionKinase
OrganismAnas platyrhynchos platyrhynchos (Northern mallard)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Anseriformes> Anatidae> Anatinae> Anas.
Aromaticity0.07
Grand average of hydropathy-0.414
Instability index55.32
Isoelectric point7.53
Molecular weight241965.09
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32869
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     604.55|     100|     101|    1795|    1894|       1
---------------------------------------------------------------------------
 1633- 1719 (92.77/40.40)	.......PLPKQtcdiitCEPMGS.............LID.TKGNKIAGFDSID....KKQKQGLQVSTK.................QKVSPWD..LFEGHKNPA...PLS....WAWFGTVRVDRKVIKYEEQQHLL....
 1720- 1790 (78.30/32.96)	.....LY................................HtHPK...............PKPRSYYLEPLPL.......PP....EEEEEEPTTpvSQEPERKSG...ELSD...QGKHG.MDDEKKTKG.RKRKSKSSSRT
 1795- 1894 (178.13/84.33)	QN..NLYRVPPN......YSPISS............QMMH.HPQSALWGYNIMG....QPQQPGFFVQNQPL.......PP....GGSRLDPTS..SFVPTNTKQ...ALSN.MLQRRSGTMMQPPSIHAITPQQQLLQMKL
 1897- 1981 (112.75/50.68)	QQaqNMVHIQYC......YEGMPS............LTVA.LKFS..WGYT.MY....STQMP...LQQQ.........QP....GGVVLSP....SYNPRAYTA...AHSGpALMERLRQMQQQPS..GYIQQQA......
 1986- 2036 (47.83/17.27)	..........................................................QPLAGTQRLSHQPL.......QPnsliGGG.LDSAS..TTGP.......................HPNLNSAQLPQEQMRQRQQ
 2040- 2153 (94.77/41.43)	QQ..RLFQVRDP......TAPKRPlgirvkistsvfQLQQ.GQQQGQQQPQTLGlqpvQPQQPLNLVQNQVLkckdlvvPQ....QQDKQFPRQ..GLQQTQQQQqtaALVR.QLQKQ.........LSSNQPQQGVNQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     129.97|      30|     147|     909|     938|       2
---------------------------------------------------------------------------
  909-  935 (43.45/24.04)	....................CLILNSEQTAQVFEGLCGVVKHV..VNPS
  936-  977 (26.56/11.73)	ECS.spercilaylydlyvsCSHLRS.KFGDLFSSACSKVKQT..I...
 1058- 1085 (31.59/15.39)	....................CTVLSSEWLG.VVKALCCSSNHVwgFNDL
 1086- 1126 (28.37/13.05)	LCSvdvsdlsfhdslatfiaILIAR.....QCF.SLEDVVQHV..ALPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.13|      28|     656|     323|     352|       3
---------------------------------------------------------------------------
  323-  352 (50.52/41.75)	PQHRPLVYGLSCMLQTVTlcCPSALVWNYS
  983- 1010 (53.62/36.36)	PSNSNLLWDPEFMLDFIE..NPSAHSINYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.62|      35|     147|    1200|    1241|       4
---------------------------------------------------------------------------
 1200- 1241 (56.06/39.74)	LMLGD..AEIGSSSVNPlksedftMRGLLEDLNED..EMWGSSHTL
 1348- 1386 (48.55/23.37)	LMIKQcmKESGSGSVAE.......MNSLLDNIAKAtiEVFQQSADL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.75|      47|     282|     355|     404|       8
---------------------------------------------------------------------------
  355-  404 (78.21/56.51)	ENKNINPGSPLDLLQVAPSSL....PMPG.....GNSSFNQQVRAkiyEVEQQIK.QRGR
  634-  690 (66.54/40.12)	EHMGIDSGTTSIFDDVDKSDFkifsPMPGescenMNSSLDRRISV...TSEKSVKrERLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.67|      35|     234|    1157|    1193|      12
---------------------------------------------------------------------------
 1157- 1193 (55.28/54.61)	VCLF.PQETGKLfPGIRSSCDRH.......LLAAAHNSIEvGAVF
 1395- 1437 (48.39/36.06)	IGLFnPNSVGNA.DTISSSSERRgvwlvapLIAKLPTSVQ.GRVL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32869 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PLAGTQRLSHQPLQPNSLIGGGLDSASTTGPHPNLNSAQLPQEQMRQRQQQIRQQRLFQLQQGQQQGQQQPQTLGLQPVQPQQPLQFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVNQYGHPSHF
2) RSYYLEPLPLPPEEEEEEPTTPVSQEPERKSGELSDQGKHGMDDEKKTKGRKRKSKSSSRTDEYPQNNLYRVPPNYSPISSQMMHHPQSALWGYNIMGQPQQPGFFVQNQPLPPGGSRLDPTSSFVPTNTKQALSNMLQRRSGTMMQPPSIHAITPQQQLLQMKLLQQEQQQQQQRLLRQQAQARSLQQGQPMDQAALFTPQVRPPAQLPQYPGLQQAQSMPHGYTMYSTQMPLQQQQPGGVVLSPSYNPRAYTAAHSGPALMERLRQMQQQPSGYIQQQAA
1847
1561
1976
1842










Molecular Recognition Features






MoRF SequenceStartStop




1) RSYYLEPLPLP
1561
1571