<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP32868

Description Mediator complex subunit 23
SequenceQDSEILGVFLEVWEKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEWFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRISLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENGIITHFSVQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNAREDNPWIPDDIYYCKLIGRLSLSPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMGCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADQYSSHLNYMDPICDFLYHMKYMFTGDSVKDQQVEKIICNLRPALKLRLRFITHISKMEPAAVPQQPLSNGSPAPQPSQVPVNVALPVTQ
Length1375
PositionTail
OrganismAnas platyrhynchos platyrhynchos (Northern mallard)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Anseriformes> Anatidae> Anatinae> Anas.
Aromaticity0.10
Grand average of hydropathy-0.020
Instability index45.04
Isoelectric point7.47
Molecular weight157418.24
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP32868
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.80|      54|     603|     699|     756|       1
---------------------------------------------------------------------------
  699-  756 (88.91/57.93)	HVTDFFTGsDSIQGtwcKDILQTIMSFTPH.....NWASHTLSCFPA..PLQVFFKQNNVPQESR
 1304- 1364 (86.89/44.55)	HMKYMFTG.DSVKD...QQVEKIICNLRPAlklrlRFITHISKMEPAavPQQPLSNGSPAPQPSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     341|     350|       2
---------------------------------------------------------------------------
  341-  350 (18.69/ 9.97)	IFFVLFQFAS
  374-  383 (19.45/10.67)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     251.77|      77|     603|     208|     295|       3
---------------------------------------------------------------------------
  208-  292 (122.01/87.19)	DF.VDTFRPTARINSIcGRCslLPVVNNsgaMCnsWKLDPTTL.RFPLKGLLPYDKKDLFEPQTA..LLRYVLEQPYSRDMVCNMLGLN
  403-  435 (44.84/18.12)	..........................................L.LYPEKECIPV..PDINKPQST...........HAFAMTCIWIHLN
  831-  896 (84.92/42.60)	DFlVYEFSTSAGGQQL.NKC..IEILND...MV..WKYNIVTLdRLIL..CLAMRSHEGNEAQVCyfIIQLLLLKP.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.96|      23|     603|      31|      77|       4
---------------------------------------------------------------------------
   45-   74 (33.04/59.15)	FRQfWSSLSQESHeqcvqwIVRFIHSQHSP
  767-  789 (43.92/13.70)	YRK.WKSMTNENG......IITHFSVQGSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.27|      16|     571|     586|     605|       5
---------------------------------------------------------------------------
  586-  605 (25.98/22.76)	GFISQLLPTVFkshaWGILH
 1154- 1169 (31.29/16.95)	GLIITALPEPY....WIVLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.99|      22|     907|     111|     138|       7
---------------------------------------------------------------------------
  111-  137 (28.71/29.99)	ERTQlwaLTFKLVRKIIGGVdyKGVRD
 1021- 1042 (39.27/17.55)	ERTN...LKRKLVHAIIGSL..KDNRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.07|      14|     603|     625|     647|       8
---------------------------------------------------------------------------
  625-  638 (23.82/29.80)	QLLSHLHSLAAVPQ
  654-  667 (23.25/ 6.02)	RLITALGSSEVQPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.60|      31|     303|     940|    1009|       9
---------------------------------------------------------------------------
  175-  205 (57.44/17.68)	NACL..LPAY.FAVTEIRKLYPEGKLPHWLLGNL
  961-  994 (44.16/42.97)	NVCLrfLPVFdIVIHRFLELLPVSKSLETLLDHL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP32868 with Med23 domain of Kingdom Metazoa
Unable to open file!